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Items: 18

1.

Suppression of Human Platelet Activation via Integrin αIIbβ3 Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene.

Hsia CW, Tsai CL, Sheu JR, Lu WJ, Hsia CH, Velusamy M, Jayakumar T, Li JY.

Int J Mol Sci. 2019 Nov 8;20(22). pii: E5585. doi: 10.3390/ijms20225585.

2.

Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2-PKC-AKT Activation in Human Platelets.

Hsia CW, Lin KC, Lee TY, Hsia CH, Chou DS, Jayakumar T, Velusamy M, Chang CC, Sheu JR.

Int J Mol Sci. 2019 Jun 3;20(11). pii: E2731. doi: 10.3390/ijms20112731.

3.

Ruthenium complex, TQ‑5, protects against LPS‑induced macrophage inflammation and acute liver injury in mice via downregulating NF‑κB pathways.

Hou SM, Hsia CH, Velusamy M, Jayakumar T, Hsia CW, Chang CC, Lin KH, Lu YC.

Int J Mol Med. 2019 Jul;44(1):335-345. doi: 10.3892/ijmm.2019.4179. Epub 2019 May 3.

PMID:
31059066
4.

[Corrigendum] Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation.

Shyu KG, Velusamy M, Hsia CW, Yang CH, Hsia CH, Chou DS, Jayakumar T, Sheu JR, Li JY.

Int J Mol Med. 2019 Jul;44(1):357. doi: 10.3892/ijmm.2019.4177. Epub 2019 Apr 30.

5.
6.

Structure⁻Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases.

Yang CH, Hsia CW, Jayakumar T, Sheu JR, Hsia CH, Khamrang T, Chen YJ, Manubolu M, Chang Y.

Int J Mol Sci. 2018 Nov 19;19(11). pii: E3641. doi: 10.3390/ijms19113641.

7.

Novel Therapeutic Agent against Platelet Activation In Vitro and Arterial Thrombosis In Vivo by Morin Hydrate.

Hsia CW, Wu MP, Velusamy M, Hsia CH, Chou DS, Tsai CL, Hsu CY, Jayakumar T, Chung CL, Sheu JR.

Int J Mol Sci. 2018 Aug 13;19(8). pii: E2386. doi: 10.3390/ijms19082386.

8.

Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy.

Jayakumar T, Hsu CY, Khamrang T, Hsia CH, Hsia CW, Manubolu M, Sheu JR.

Int J Mol Sci. 2018 Jun 20;19(6). pii: E1818. doi: 10.3390/ijms19061818. Review.

9.

Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation.

Shyu RS, Khamrang T, Sheu JR, Hsia CW, Velusamy M, Hsia CH, Chou DS, Chang CC.

Bioinorg Chem Appl. 2018 May 2;2018:8291393. doi: 10.1155/2018/8291393. eCollection 2018.

10.

Structure-Antiplatelet Activity Relationships of Novel Ruthenium (II) Complexes: Investigation of Its Molecular Targets.

Hsia CH, Jayakumar T, Sheu JR, Tsao SY, Velusamy M, Hsia CW, Chou DS, Chang CC, Chung CL, Khamrang T, Lin KC.

Molecules. 2018 Feb 22;23(2). pii: E477. doi: 10.3390/molecules23020477.

11.

Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation.

Shyu KG, Velusamy M, Hsia CW, Yang CH, Hsia CH, Chou DS, Jayakumar T, Sheu JR, Li JY.

Int J Mol Med. 2018 May;41(5):2589-2600. doi: 10.3892/ijmm.2018.3472. Epub 2018 Feb 7. Erratum in: Int J Mol Med. 2019 Jul;44(1):357.

12.

Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen-integrin αIIb β3 binding in human platelets.

Hsia CH, Lu WJ, Lin KH, Chou DS, Geraldine P, Jayakuma T, Chang NC, Sheu JR.

J Cell Mol Med. 2018 Apr;22(4):2142-2152. doi: 10.1111/jcmm.13488. Epub 2018 Jan 25.

13.

New Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound.

Hsia CW, Velusamy M, Tsao JT, Hsia CH, Chou DS, Jayakumar T, Lee LW, Li JY, Sheu JR.

Int J Mol Sci. 2017 Dec 5;18(12). pii: E2616. doi: 10.3390/ijms18122616.

14.

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies.

Hsia CH, Velusamy M, Sheu JR, Khamrang T, Jayakumar T, Lu WJ, Lin KH, Chang CC.

Sci Rep. 2017 Aug 25;7(1):9556. doi: 10.1038/s41598-017-09695-z.

15.

Development of Benzimidazole Derivatives as Novel Anti-platelet Drugs.

Yao W-C, Yuan L-T, Yang W-B, Hsia C-H, Huang L-T, Lee T-Y, Sheu J-R, Lu W-J, Jayakumar T, Chen R-J.

Curr Pharm Biotechnol. 2017;18(7):594-605. doi: 10.2174/1389201018666170821113430.

PMID:
28828982
16.

Antiplatelet Activity of a Newly Synthesized Novel Ruthenium (II): A Potential Role for Akt/JNK Signaling.

Khamrang T, Hung KC, Hsia CH, Hsieh CY, Velusamy M, Jayakumar T, Sheu JR.

Int J Mol Sci. 2017 Apr 27;18(5). pii: E916. doi: 10.3390/ijms18050916.

17.

A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice.

Sheu JR, Chen ZC, Jayakumar T, Chou DS, Yen TL, Lee HN, Pan SH, Hsia CH, Yang CH, Hsieh CY.

Sci Rep. 2017 Feb 6;7:42277. doi: 10.1038/srep42277.

18.

Effect of Antrodia camphorata on inflammatory arterial thrombosis-mediated platelet activation: the pivotal role of protein kinase C.

Lu WJ, Lin SC, Lan CC, Lee TY, Hsia CH, Huang YK, Lee HC, Sheu JR.

ScientificWorldJournal. 2014;2014:745802. doi: 10.1155/2014/745802. Epub 2014 Oct 14.

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