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Items: 1 to 20 of 23


A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer.

Ruzzolini J, Laurenzana A, Andreucci E, Peppicelli S, Bianchini F, Carta F, Supuran CT, Romanelli MN, Nediani C, Calorini L.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):391-397. doi: 10.1080/14756366.2019.1706090.


Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases.

Nediani C, Ruzzolini J, Romani A, Calorini L.

Antioxidants (Basel). 2019 Nov 22;8(12). pii: E578. doi: 10.3390/antiox8120578. Review.


Health Effects of Phenolic Compounds Found in Extra-Virgin Olive Oil, By-Products, and Leaf of Olea europaea L.

Romani A, Ieri F, Urciuoli S, Noce A, Marrone G, Nediani C, Bernini R.

Nutrients. 2019 Aug 1;11(8). pii: E1776. doi: 10.3390/nu11081776.


Anoikis Resistance as a Further Trait of Acidic-Adapted Melanoma Cells.

Peppicelli S, Ruzzolini J, Bianchini F, Andreucci E, Nediani C, Laurenzana A, Margheri F, Fibbi G, Calorini L.

J Oncol. 2019 Jun 2;2019:8340926. doi: 10.1155/2019/8340926. eCollection 2019.


Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies.

Ruzzolini J, Peppicelli S, Andreucci E, Bianchini F, Scardigli A, Romani A, la Marca G, Nediani C, Calorini L.

Nutrients. 2018 Dec 8;10(12). pii: E1950. doi: 10.3390/nu10121950.


Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB.

Miceli C, Santin Y, Manzella N, Coppini R, Berti A, Stefani M, Parini A, Mialet-Perez J, Nediani C.

Oxid Med Cell Longev. 2018 Mar 26;2018:8067592. doi: 10.1155/2018/8067592. eCollection 2018.


Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target.

Manni ME, Rigacci S, Borchi E, Bargelli V, Miceli C, Giordano C, Raimondi L, Nediani C.

Oxid Med Cell Longev. 2016;2016:4375418. doi: 10.1155/2016/4375418. Epub 2016 Dec 1.


The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study.

Luccarini I, Pantano D, Nardiello P, Cavone L, Lapucci A, Miceli C, Nediani C, Berti A, Stefani M, Casamenti F.

J Alzheimers Dis. 2016 Sep 6;54(2):737-50. doi: 10.3233/JAD-160471.


Impaired mitochondrial biogenesis is a common feature to myocardial hypertrophy and end-stage ischemic heart failure.

Pisano A, Cerbelli B, Perli E, Pelullo M, Bargelli V, Preziuso C, Mancini M, He L, Bates MG, Lucena JR, Della Monica PL, Familiari G, Petrozza V, Nediani C, Taylor RW, d'Amati G, Giordano C.

Cardiovasc Pathol. 2016 Mar-Apr;25(2):103-12. doi: 10.1016/j.carpath.2015.09.009. Epub 2015 Sep 30.


Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight.

Rigacci S, Miceli C, Nediani C, Berti A, Cascella R, Pantano D, Nardiello P, Luccarini I, Casamenti F, Stefani M.

Oncotarget. 2015 Nov 3;6(34):35344-57. doi: 10.18632/oncotarget.6119.


Mild exposure of RIN-5F β-cells to human islet amyloid polypeptide aggregates upregulates antioxidant enzymes via NADPH oxidase-RAGE: an hormetic stimulus.

Borchi E, Bargelli V, Guidotti V, Berti A, Stefani M, Nediani C, Rigacci S.

Redox Biol. 2013 Dec 17;2:114-22. doi: 10.1016/j.redox.2013.12.005. eCollection 2013.


Early hemodynamic and biochemical changes in overloaded swine ventricle.

Gelsomino S, Lucà F, Nediani C, Orlandini SZ, Bani D, Rubino AS, Renzulli A, Lorusso R, Consolo A, Lo Cascio A, Maessen J, Gensini GF.

Tex Heart Inst J. 2013;40(3):235-45.


p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice.

Villeneuve C, Guilbeau-Frugier C, Sicard P, Lairez O, Ordener C, Duparc T, De Paulis D, Couderc B, Spreux-Varoquaux O, Tortosa F, Garnier A, Knauf C, Valet P, Borchi E, Nediani C, Gharib A, Ovize M, Delisle MB, Parini A, Mialet-Perez J.

Antioxid Redox Signal. 2013 Jan 1;18(1):5-18. doi: 10.1089/ars.2011.4373. Epub 2012 Aug 10.


Nitric oxide/reactive oxygen species generation and nitroso/redox imbalance in heart failure: from molecular mechanisms to therapeutic implications.

Nediani C, Raimondi L, Borchi E, Cerbai E.

Antioxid Redox Signal. 2011 Jan 15;14(2):289-331. doi: 10.1089/ars.2010.3198. Epub 2010 Sep 29. Review.


Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure.

Borchi E, Bargelli V, Stillitano F, Giordano C, Sebastiani M, Nassi PA, d'Amati G, Cerbai E, Nediani C.

Biochim Biophys Acta. 2010 Mar;1802(3):331-8. doi: 10.1016/j.bbadis.2009.10.014. Epub 2009 Nov 3.


Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.

Rigacci S, Guidotti V, Bucciantini M, Parri M, Nediani C, Cerbai E, Stefani M, Berti A.

J Nutr Biochem. 2010 Aug;21(8):726-35. doi: 10.1016/j.jnutbio.2009.04.010. Epub 2009 Jul 18.


Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia-reperfusion.

Borchi E, Parri M, Papucci L, Becatti M, Nassi N, Nassi P, Nediani C.

J Cell Mol Med. 2009 Aug;13(8B):2724-35. doi: 10.1111/j.1582-4934.2008.00485.x.


Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies.

Sebastiani M, Giordano C, Nediani C, Travaglini C, Borchi E, Zani M, Feccia M, Mancini M, Petrozza V, Cossarizza A, Gallo P, Taylor RW, d'Amati G.

J Am Coll Cardiol. 2007 Oct 2;50(14):1362-9. Epub 2007 Sep 17.


NADPH oxidase-dependent redox signaling in human heart failure: relationship between the left and right ventricle.

Nediani C, Borchi E, Giordano C, Baruzzo S, Ponziani V, Sebastiani M, Nassi P, Mugelli A, d'Amati G, Cerbai E.

J Mol Cell Cardiol. 2007 Apr;42(4):826-34. Epub 2007 Jan 31.


Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation.

Fiorillo C, Ponziani V, Giannini L, Cecchi C, Celli A, Nediani C, Perna AM, Liguori P, Nassi N, Formigli L, Tani A, Nassi P.

Free Radic Res. 2003 Mar;37(3):331-9.


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