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Items: 1 to 20 of 47

1.
2.

Interdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding.

Carter CW Jr, Wills PR.

Mol Biol Evol. 2018 Feb 1;35(2):269-286. doi: 10.1093/molbev/msx265.

3.

Insuperable problems of the genetic code initially emerging in an RNA world.

Wills PR, Carter CW Jr.

Biosystems. 2018 Feb;164:155-166. doi: 10.1016/j.biosystems.2017.09.006. Epub 2017 Sep 10. Review.

4.

Coding of Class I and II Aminoacyl-tRNA Synthetases.

Carter CW Jr.

Adv Exp Med Biol. 2017;966:103-148. doi: 10.1007/5584_2017_93. Review.

5.

An Alternative to the RNA World.

Carter CW Jr.

Nat Hist. 2016 Dec;125(1):28-33. No abstract available.

6.

High-Dimensional Mutant and Modular Thermodynamic Cycles, Molecular Switching, and Free Energy Transduction.

Carter CW Jr.

Annu Rev Biophys. 2017 May 22;46:433-453. doi: 10.1146/annurev-biophys-070816-033811. Epub 2017 Mar 24. Review.

7.

Augmenting the anisotropic network model with torsional potentials improves PATH performance, enabling detailed comparison with experimental rate data.

Chandrasekaran SN, Carter CW Jr.

Struct Dyn. 2017 Feb 16;4(3):032103. doi: 10.1063/1.4976142. eCollection 2017 May.

8.

Combining multi-mutant and modular thermodynamic cycles to measure energetic coupling networks in enzyme catalysis.

Carter CW Jr, Chandrasekaran SN, Weinreb V, Li L, Williams T.

Struct Dyn. 2017 Jan 26;4(3):032101. doi: 10.1063/1.4974218. eCollection 2017 May.

9.

Functional Class I and II amino acid-activating enzymes can be coded by opposite strands of the same gene.

Martinez-Rodriguez L, Erdogan O, Jimenez-Rodriguez M, Gonzalez-Rivera K, Williams T, Li L, Weinreb V, Collier M, Chandrasekaran SN, Ambroggio X, Kuhlman B, Carter CW Jr.

J Biol Chem. 2016 Nov 4;291(45):23830-23831. No abstract available.

10.

An Ancestral Tryptophanyl-tRNA Synthetase Precursor Achieves High Catalytic Rate Enhancement without Ordered Ground-State Tertiary Structures.

Sapienza PJ, Li L, Williams T, Lee AL, Carter CW Jr.

ACS Chem Biol. 2016 Jun 17;11(6):1661-8. doi: 10.1021/acschembio.5b01011. Epub 2016 Apr 7.

11.

A modified PATH algorithm rapidly generates transition states comparable to those found by other well established algorithms.

Chandrasekaran SN, Das J, Dokholyan NV, Carter CW Jr.

Struct Dyn. 2016 Feb 24;3(1):012101. doi: 10.1063/1.4941599. eCollection 2016 Jan.

12.

tRNA acceptor-stem and anticodon bases embed separate features of amino acid chemistry.

Carter CW Jr, Wolfenden R.

RNA Biol. 2016;13(2):145-51. doi: 10.1080/15476286.2015.1112488. Epub 2015 Nov 23.

13.

Selective Inhibition of Bacterial Tryptophanyl-tRNA Synthetases by Indolmycin Is Mechanism-based.

Williams TL, Yin YW, Carter CW Jr.

J Biol Chem. 2016 Jan 1;291(1):255-65. doi: 10.1074/jbc.M115.690321. Epub 2015 Nov 9.

14.

Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene.

Martinez-Rodriguez L, Erdogan O, Jimenez-Rodriguez M, Gonzalez-Rivera K, Williams T, Li L, Weinreb V, Collier M, Chandrasekaran SN, Ambroggio X, Kuhlman B, Carter CW Jr.

J Biol Chem. 2015 Aug 7;290(32):19710-25. doi: 10.1074/jbc.M115.642876. Epub 2015 Jun 18. Erratum in: J Biol Chem. 2016 Nov 4;291(45):23830-23831.

15.

tRNA acceptor stem and anticodon bases form independent codes related to protein folding.

Carter CW Jr, Wolfenden R.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7489-94. doi: 10.1073/pnas.1507569112. Epub 2015 Jun 1.

16.

Temperature dependence of amino acid hydrophobicities.

Wolfenden R, Lewis CA Jr, Yuan Y, Carter CW Jr.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7484-8. doi: 10.1073/pnas.1507565112. Epub 2015 Jun 1.

17.

What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental Attention.

Carter CW.

Life (Basel). 2015 Jan 23;5(1):294-320. doi: 10.3390/life5010294. Review.

18.

Urzymology: experimental access to a key transition in the appearance of enzymes.

Carter CW Jr.

J Biol Chem. 2014 Oct 31;289(44):30213-20. doi: 10.1074/jbc.R114.567495. Epub 2014 Sep 10. Review.

19.

The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.

Carter CW Jr, Li L, Weinreb V, Collier M, Gonzalez-Rivera K, Jimenez-Rodriguez M, Erdogan O, Kuhlman B, Ambroggio X, Williams T, Chandrasekharan SN.

Biol Direct. 2014 Jun 14;9:11. doi: 10.1186/1745-6150-9-11.

20.

Enhanced amino acid selection in fully evolved tryptophanyl-tRNA synthetase, relative to its urzyme, requires domain motion sensed by the D1 switch, a remote dynamic packing motif.

Weinreb V, Li L, Chandrasekaran SN, Koehl P, Delarue M, Carter CW Jr.

J Biol Chem. 2014 Feb 14;289(7):4367-76. doi: 10.1074/jbc.M113.538660. Epub 2014 Jan 6.

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