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Items: 1 to 20 of 207


Author Correction: Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank.

Meng W, Adams MJ, Palmer CNA; 23andMe Research Team, Shi J, Auton A, Ryan KA, Jordan JM, Mitchell BD, Jackson RD, Yau MS, McIntosh AM, Smith BH.

Commun Biol. 2020 Mar 26;3(1):149. doi: 10.1038/s42003-020-0880-x.


Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.

Hollis B, Day FR, Busch AS, Thompson DJ, Soares ALG, Timmers PRHJ, Kwong A, Easton DF, Joshi PK, Timpson NJ; PRACTICAL Consortium; 23andMe Research Team, Ong KK, Perry JRB.

Nat Commun. 2020 Mar 24;11(1):1536. doi: 10.1038/s41467-020-14451-5.


Correction to: Overlapping genetic architecture between Parkinson disease and melanoma.

Dube U, Ibanez L, Budde JP, Benitez BA, Davis AA, Harari O, Iles MM, Law MH, Brown KM; 23andMe Research Team; Melanoma-Meta-analysis Consortium, Cruchaga C.

Acta Neuropathol. 2020 Mar 14. doi: 10.1007/s00401-020-02143-9. [Epub ahead of print]


Maresin Conjugates in Tissue Regeneration 1 improves alveolar fluid clearance by up-regulating alveolar ENaC, Na, K-ATPase in lipopolysaccharide-induced acute lung injury.

Han J, Li H, Bhandari S, Cao F, Wang XY, Tian C, Li XY, Zhang PH, Liu YJ, Wu CH, Smith FG, Jin SW, Hao Y.

J Cell Mol Med. 2020 Mar 11. doi: 10.1111/jcmm.15146. [Epub ahead of print]


PCTR1 ameliorates lipopolysaccharide-induced acute inflammation and multiple organ damage via regulation of linoleic acid metabolism by promoting FADS1/FASDS2/ELOV2 expression and reducing PLA2 expression.

Liu YJ, Li H, Tian Y, Han J, Wang XY, Li XY, Tian C, Zhang PH, Hao Y, Gao F, Jin SW.

Lab Invest. 2020 Mar 2. doi: 10.1038/s41374-020-0412-9. [Epub ahead of print]


Gompertz tracking of the growth trajectories of the human-liver-cancer xenograft-tumors in nude mice.

Yang D, Gao P, Tian C, Sheng Y.

Comput Methods Programs Biomed. 2020 Feb 21;191:105412. doi: 10.1016/j.cmpb.2020.105412. [Epub ahead of print]


Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure.

Arvanitis M, Tampakakis E, Zhang Y, Wang W, Auton A; 23andMe Research Team, Dutta D, Glavaris S, Keramati A, Chatterjee N, Chi NC, Ren B, Post WS, Battle A.

Nat Commun. 2020 Feb 28;11(1):1122. doi: 10.1038/s41467-020-14843-7.


Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson's disease.

Smolensky L, Amondikar N, Crawford K, Neu S, Kopil CM, Daeschler M, Riley L; 23andMe Research Team, Brown E, Toga AW, Tanner C.

Sci Data. 2020 Feb 24;7(1):67. doi: 10.1038/s41597-020-0401-2.


Design, synthesis and biological activity of N5-substituted tetrahydropteroate analogs as non-classical antifolates against cobalamin-dependent methionine synthase and potential anticancer agents.

Wang M, Tian C, Xue L, Li H, Cong J, Fang F, Yang J, Yuan M, Chen Y, Guo Y, Wang X, Liu J, Zhang Z.

Eur J Med Chem. 2020 Mar 15;190:112113. doi: 10.1016/j.ejmech.2020.112113. Epub 2020 Feb 5.


Dynamic Fracture and Fragmentation Characteristics of Metal Cylinder and Rings Subjected to Internal Explosive Loading.

An X, Ye P, Liu J, Tian C, Feng S, Dong Y.

Materials (Basel). 2020 Feb 8;13(3). pii: E778. doi: 10.3390/ma13030778.


Excess salt intake promotes M1 microglia polarization via a p38/MAPK/AR-dependent pathway after cerebral ischemia in mice.

Zhang T, Wang D, Li X, Jiang Y, Wang C, Zhang Y, Kong Q, Tian C, Dai Y, Zhao W, Jiang M, Chang Y, Wang G.

Int Immunopharmacol. 2020 Feb 7;81:106176. doi: 10.1016/j.intimp.2019.106176. [Epub ahead of print]


Nomogram for predicting overall survival in stage II-III colorectal cancer.

Liu J, Huang X, Yang W, Li C, Li Z, Zhang C, Chen S, Wu G, Xie W, Wei C, Tian C, Huang L, Jeen F, Mo X, Tang W.

Cancer Med. 2020 Apr;9(7):2363-2371. doi: 10.1002/cam4.2896. Epub 2020 Feb 6.


A Pooled Analysis of the Prognostic Significance of Brugada Syndrome with Atrial Fibrillation.

Tian C, An N, Yuan M, Wang L, Zhang H, Li X, Yang X, Li Y, Kusano KF, Gao Y, Xing Y.

Curr Pharm Des. 2020;26(1):129-137. doi: 10.2174/1381612826666200114112029.


Nomogram based on clinical characteristics for preoperative prediction of perineural invasion in gastric cancer.

Liu J, Huang X, Chen S, Wu G, Xie W, Franco JPC, Zhang C, Huang L, Tian C, Tang W.

J Int Med Res. 2020 Jan;48(1):300060519895131. doi: 10.1177/0300060519895131. No abstract available.


WITHDRAWN: Overexpression of GLI2 induces odontogenic differentiation in human dental pulp stem cells through activation of the Wnt/β-catenin signaling pathway.

Zheng H, Tian C, Zeng X, Liu T.

Life Sci. 2019 Dec 17:117178. doi: 10.1016/j.lfs.2019.117178. [Epub ahead of print]


Overlapping genetic architecture between Parkinson disease and melanoma.

Dube U, Ibanez L, Budde JP, Benitez BA, Davis AA, Harari O, Iles MM, Law MH, Brown KM; 23andMe Research Team; Melanoma-Meta-analysis Consortium, Cruchaga C.

Acta Neuropathol. 2020 Feb;139(2):347-364. doi: 10.1007/s00401-019-02110-z. Epub 2019 Dec 16. Erratum in: Acta Neuropathol. 2020 Mar 14;:.


Effects of amendments and aided phytostabilization of an energy crop on the metal availability and leaching in mine tailings using a pot test.

Gao B, Zhang X, Tian C, Zhang X, Liu J.

Environ Sci Pollut Res Int. 2020 Jan;27(3):2745-2759. doi: 10.1007/s11356-019-07171-x. Epub 2019 Dec 13.


Transient Receptor Potential Ankyrin 1 Contributes to Lysophosphatidylcholine-Induced Intracellular Calcium Regulation and THP-1-Derived Macrophage Activation.

Tian C, Huang R, Tang F, Lin Z, Cheng N, Han X, Li S, Zhou P, Deng S, Huang H, Zhao H, Xu J, Li Z.

J Membr Biol. 2020 Feb;253(1):43-55. doi: 10.1007/s00232-019-00104-2. Epub 2019 Dec 10.


Insights into the genetic basis of retinal detachment.

Boutin TS, Charteris DG, Chandra A, Campbell S, Hayward C, Campbell A; UK Biobank Eye & Vision Consortium, Nandakumar P, Hinds D; 23andMe Research Team , Mitry D, Vitart V.

Hum Mol Genet. 2020 Mar 13;29(4):689-702. doi: 10.1093/hmg/ddz294.


Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson's disease.

Leonard H, Blauwendraat C, Krohn L, Faghri F, Iwaki H, Ferguson G, Day-Williams AG, Stone DJ, Singleton AB, Nalls MA, Gan-Or Z; International Parkinson's Disease Genomic Consortium (IPDGC).

J Med Genet. 2019 Nov 29. pii: jmedgenet-2019-106283. doi: 10.1136/jmedgenet-2019-106283. [Epub ahead of print]


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