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Items: 1 to 20 of 21


Differential contribution of protein phosphatase 1α to cell transformation of different cell types.

Chen JM, Chen KC, Chiu SC, Chen RY, Hsia JY, Huang YJ, Yu CR.

Oncol Rep. 2019 Aug 8. doi: 10.3892/or.2019.7272. [Epub ahead of print]


Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of suppressed in lung cancer.

Chiu SC, Chen KC, Hsia JY, Chuang CY, Wan CX, Wei TW, Huang YJ, Chen JM, Liao YA, Yu CR.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C600-C612. doi: 10.1152/ajpcell.00032.2019. Epub 2019 Jul 17.


Arecoline Promotes Migration of A549 Lung Cancer Cells through Activating the EGFR/Src/FAK Pathway.

Chang CH, Chen MC, Chiu TH, Li YH, Yu WC, Liao WL, Oner M, Yu CR, Wu CC, Yang TY, Teng CJ, Chiu KY, Chen KC, Wang HY, Yue CH, Lai CH, Hsieh JT, Lin H.

Toxins (Basel). 2019 Mar 28;11(4). pii: E185. doi: 10.3390/toxins11040185.


Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA.

Wei TW, Wu PY, Wu TJ, Hou HA, Chou WC, Teng CJ, Lin CR, Chen JM, Lin TY, Su HC, Huang CF, Yu CR, Hsu SL, Tien HF, Tsai MD.

Cancer Res. 2017 Jan 15;77(2):494-508. doi: 10.1158/0008-5472.CAN-16-1004. Epub 2016 Nov 10.


The involvement of nuclear factor-κappaB in the nuclear targeting and cyclin E1 upregulating activities of hepatoma upregulated protein.

Chen JM, Chiu SC, Wei TY, Lin SY, Chong CM, Wu CC, Huang JY, Yang ST, Ku CF, Hsia JY, Yu CT.

Cell Signal. 2015 Jan;27(1):26-36. doi: 10.1016/j.cellsig.2014.09.020. Epub 2014 Oct 5.


Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.

Wei TY, Hsia JY, Chiu SC, Su LJ, Juan CC, Lee YC, Chen JM, Chou HY, Huang JY, Huang HM, Yu CT.

Cell Signal. 2014 Dec;26(12):2940-50. doi: 10.1016/j.cellsig.2014.09.014. Epub 2014 Sep 30.


The mitosis-regulating and protein-protein interaction activities of astrin are controlled by aurora-A-induced phosphorylation.

Chiu SC, Chen JM, Wei TY, Cheng TS, Wang YH, Ku CF, Lian CH, Liu CC, Kuo YC, Yu CT.

Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C466-78. doi: 10.1152/ajpcell.00164.2014. Epub 2014 Jul 9.


Effector mechanisms of sunitinib-induced G1 cell cycle arrest, differentiation, and apoptosis in human acute myeloid leukaemia HL60 and KG-1 cells.

Teng CL, Yu CT, Hwang WL, Tsai JR, Liu HC, Hwang GY, Hsu SL.

Ann Hematol. 2013 Mar;92(3):301-13. doi: 10.1007/s00277-012-1627-7. Epub 2012 Nov 20.


p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation.

Wu CC, Yang TY, Yu CT, Phan L, Ivan C, Sood AK, Hsu SL, Lee MH.

Cell Cycle. 2012 Sep 15;11(18):3433-42. doi: 10.4161/cc.21732. Epub 2012 Aug 16.


Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.

Wei TY, Juan CC, Hisa JY, Su LJ, Lee YC, Chou HY, Chen JM, Wu YC, Chiu SC, Hsu CP, Liu KL, Yu CT.

Cancer Sci. 2012 Sep;103(9):1640-50. doi: 10.1111/j.1349-7006.2012.02367.x. Epub 2012 Aug 8.


The novel protein suppressed in lung cancer down-regulated in lung cancer tissues retards cell proliferation and inhibits the oncokinase Aurora-A.

Yu CT, Hsia JY, Hseih YC, Su LJ, Lee TC, Ku CF, Chen KS, Chen JM, Wei TY, Lee YC, Huang CY, Wu YC, Yang CY, Hsu SL.

J Thorac Oncol. 2011 Jun;6(6):988-97. doi: 10.1097/JTO.0b013e318212692e.


Aurora-A promotes gefitinib resistance via a NF-κB signaling pathway in p53 knockdown lung cancer cells.

Wu CC, Yu CT, Chang GC, Lai JM, Hsu SL.

Biochem Biophys Res Commun. 2011 Feb 11;405(2):168-72. doi: 10.1016/j.bbrc.2011.01.001. Epub 2011 Jan 7.


An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells.

Chang GC, Yu CT, Tsai CH, Tsai JR, Chen JC, Wu CC, Wu WJ, Hsu SL.

Eur J Pharmacol. 2008 Dec 14;600(1-3):37-44. doi: 10.1016/j.ejphar.2008.10.024. Epub 2008 Oct 21.


Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin.

Cheng TS, Hsiao YL, Lin CC, Yu CT, Hsu CM, Chang MS, Lee CI, Huang CY, Howng SL, Hong YR.

J Biol Chem. 2008 Jan 25;283(4):2454-64. Epub 2007 Nov 30.


Identification of c-Fos as a mitotic phosphoprotein: regulation of c-Fos by Aurora-A.

Yu CT, Wu JC, Liao MC, Hsu SL, Huang CY.

J Biomed Sci. 2008 Jan;15(1):79-87. Epub 2007 Oct 10.


Characterization of cocaine-elicited cell vacuolation: the involvement of calcium/calmodulin in organelle deregulation.

Yu CT, Li JH, Lee TC, Lin LF.

J Biomed Sci. 2008 Mar;15(2):215-26. Epub 2007 Oct 7.


Gene expression profiles of the aurora family kinases.

Lin YS, Su LJ, Yu CT, Wong FH, Yeh HH, Chen SL, Wu JC, Lin WJ, Shiue YL, Liu HS, Hsu SL, Lai JM, Huang CY.

Gene Expr. 2006;13(1):15-26.


Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells.

Cherng SH, Hsu SL, Yang JL, Yu CT, Lee H.

Toxicol Lett. 2006 Mar 1;161(3):236-43. Epub 2005 Nov 8.


Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A.

Yu CT, Hsu JM, Lee YC, Tsou AP, Chou CK, Huang CY.

Mol Cell Biol. 2005 Jul;25(14):5789-800.


Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening.

Wu JC, Chen TY, Yu CT, Tsai SJ, Hsu JM, Tang MJ, Chou CK, Lin WJ, Yuan CJ, Huang CY.

J Biol Chem. 2005 Mar 11;280(10):9013-22. Epub 2005 Jan 5.

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