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Items: 1 to 20 of 33

1.

A Peptide Inhibitor of NADPH Oxidase (NOX2) Activation Markedly Decreases Mouse Lung Injury and Mortality Following Administration of Lipopolysaccharide (LPS).

Fisher AB, Dodia C, Chatterjee S, Feinstein SI.

Int J Mol Sci. 2019 May 15;20(10). pii: E2395. doi: 10.3390/ijms20102395.

2.

Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA₂ Activity Similar to the Human Orthologue.

Bannitz-Fernandes R, Aleixo-Silva R, Silva JP, Dodia C, Vazquez-Medina JP, Tao JQ, Fisher A, Netto L.

Antioxidants (Basel). 2019 Mar 1;8(3). pii: E52. doi: 10.3390/antiox8030052.

3.

Genetic inactivation of the phospholipase A2 activity of peroxiredoxin 6 in mice protects against LPS-induced acute lung injury.

Vázquez-Medina JP, Tao JQ, Patel P, Bannitz-Fernandes R, Dodia C, Sorokina EM, Feinstein SI, Chatterjee S, Fisher AB.

Am J Physiol Lung Cell Mol Physiol. 2019 Apr 1;316(4):L656-L668. doi: 10.1152/ajplung.00344.2018. Epub 2019 Jan 31.

PMID:
30702344
4.

Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A₂ Activity at Cytoplasmic pH.

Zhou S, Dodia C, Feinstein SI, Harper S, Forman HJ, Speicher DW, Fisher AB.

Antioxidants (Basel). 2018 Dec 24;8(1). pii: E4. doi: 10.3390/antiox8010004.

5.

Identification of Small Peptides that Inhibit NADPH Oxidase (Nox2) Activation.

Fisher AB, Dodia C, Feinstein SI.

Antioxidants (Basel). 2018 Dec 5;7(12). pii: E181. doi: 10.3390/antiox7120181.

6.

Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid.

Kuda O, Brezinova M, Silhavy J, Landa V, Zidek V, Dodia C, Kreuchwig F, Vrbacky M, Balas L, Durand T, Hübner N, Fisher AB, Kopecky J, Pravenec M.

Diabetes. 2018 Jun;67(6):1190-1199. doi: 10.2337/db17-1087. Epub 2018 Mar 16.

7.

Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A2 activity impair the in vitro sperm fertilizing competence in mice.

Moawad AR, Fernandez MC, Scarlata E, Dodia C, Feinstein SI, Fisher AB, O'Flaherty C.

Sci Rep. 2017 Oct 11;7(1):12994. doi: 10.1038/s41598-017-13411-2.

8.

Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes.

Fisher AB, Vasquez-Medina JP, Dodia C, Sorokina EM, Tao JQ, Feinstein SI.

Redox Biol. 2018 Apr;14:41-46. doi: 10.1016/j.redox.2017.08.008. Epub 2017 Aug 12.

9.

The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages.

Vázquez-Medina JP, Dodia C, Weng L, Mesaros C, Blair IA, Feinstein SI, Chatterjee S, Fisher AB.

FASEB J. 2016 Aug;30(8):2885-98. doi: 10.1096/fj.201500146R. Epub 2016 May 13.

10.

Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies.

Sorokina EM, Dodia C, Zhou S, Tao JQ, Gao L, Raabe T, Feinstein SI, Fisher AB.

J Biol Chem. 2016 Apr 22;291(17):9268-80. doi: 10.1074/jbc.M115.698894. Epub 2016 Feb 26.

11.

Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity.

Zhou S, Sorokina EM, Harper S, Li H, Ralat L, Dodia C, Speicher DW, Feinstein SI, Fisher AB.

Free Radic Biol Med. 2016 May;94:145-56. doi: 10.1016/j.freeradbiomed.2016.02.012. Epub 2016 Feb 16.

12.

A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6.

Fisher AB, Dodia C, Sorokina EM, Li H, Zhou S, Raabe T, Feinstein SI.

J Lipid Res. 2016 Apr;57(4):587-96. doi: 10.1194/jlr.M064758. Epub 2016 Feb 1.

13.

Binding sites for interaction of peroxiredoxin 6 with surfactant protein A.

Krishnaiah SY, Dodia C, Sorokina EM, Li H, Feinstein SI, Fisher AB.

Biochim Biophys Acta. 2016 Apr;1864(4):419-25. doi: 10.1016/j.bbapap.2015.12.009. Epub 2015 Dec 23.

14.

Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress.

Li H, Benipal B, Zhou S, Dodia C, Chatterjee S, Tao JQ, Sorokina EM, Raabe T, Feinstein SI, Fisher AB.

Free Radic Biol Med. 2015 Oct;87:356-65. doi: 10.1016/j.freeradbiomed.2015.06.009. Epub 2015 Jun 25.

15.

Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia.

Benipal B, Feinstein SI, Chatterjee S, Dodia C, Fisher AB.

Redox Biol. 2015;4:321-7. doi: 10.1016/j.redox.2015.01.011. Epub 2015 Jan 16.

16.

Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2).

Lee I, Dodia C, Chatterjee S, Feinstein SI, Fisher AB.

Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1;306(7):L635-44. doi: 10.1152/ajplung.00374.2013. Epub 2014 Jan 31.

17.

A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.

Lee I, Dodia C, Chatterjee S, Zagorski J, Mesaros C, Blair IA, Feinstein SI, Jain M, Fisher AB.

J Pharmacol Exp Ther. 2013 May;345(2):284-96. doi: 10.1124/jpet.112.201079. Epub 2013 Mar 8.

18.

p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2).

Krishnaiah SY, Dodia C, Feinstein SI, Fisher AB.

FASEB J. 2013 May;27(5):2066-73. doi: 10.1096/fj.12-222133. Epub 2013 Feb 11.

19.

Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo.

Hood ED, Greineder CF, Dodia C, Han J, Mesaros C, Shuvaev VV, Blair IA, Fisher AB, Muzykantov VR.

J Control Release. 2012 Oct 28;163(2):161-9. doi: 10.1016/j.jconrel.2012.08.031. Epub 2012 Sep 6.

20.

Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.

Rahaman H, Zhou S, Dodia C, Feinstein SI, Huang S, Speicher D, Fisher AB.

Biochemistry. 2012 Jul 10;51(27):5521-30. Epub 2012 Jun 29.

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