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Items: 1 to 20 of 60

1.

Black sea cucumber (Holothuria atra Jaeger, 1833) rescues Pseudomonas aeruginosa-infected Caenorhabditis elegans via reduction of pathogen virulence factors and enhancement of host immunity.

Lee WT, Tan BK, Eng SA, Yuen GC, Chan KL, Sim YK, Sulaiman SF, Shu-Chien AC.

Food Funct. 2019 Sep 1;10(9):5759-5767. doi: 10.1039/c9fo01357a. Epub 2019 Aug 27.

PMID:
31453615
2.

The phytochemical and anti-inflammatory studies of Dillenia suffruticosa leaves.

Abubakar S, Al-Mansoub MA, Murugaiyah V, Chan KL.

Phytother Res. 2019 Mar;33(3):660-675. doi: 10.1002/ptr.6255. Epub 2019 Jan 17.

PMID:
30653753
3.

Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: Structure-activity relationship and translating multi-potency to neuroprotection.

Liew KF, Lee EH, Chan KL, Lee CY.

Biomed Pharmacother. 2019 Feb;110:118-128. doi: 10.1016/j.biopha.2018.11.054. Epub 2018 Nov 19.

4.

Antiadipogenic effects of a standardized quassinoids-enriched fraction and eurycomanone from Eurycoma longifolia.

Balan D, Chan KL, Murugan D, AbuBakar S, Wong PF.

Phytother Res. 2018 Jul;32(7):1332-1345. doi: 10.1002/ptr.6065. Epub 2018 Mar 9.

PMID:
29520860
5.

Polar Quassinoids in Standardized Eurycoma longifolia Extract Formulated into a Lipid-Based Solid Dispersion to Improve Rat Sperm Count.

Ma HQ, Ebrahimi F, Low BS, Khan NAK, Chan KL.

Phytother Res. 2017 Dec;31(12):1875-1882. doi: 10.1002/ptr.5930. Epub 2017 Sep 26.

PMID:
28948658
6.

NMR-based plasma metabolomic discrimination for male fertility assessment of rats treated with Eurycoma longifolia extracts.

Ebrahimi F, Ibrahim B, Teh CH, Murugaiyah V, Chan KL.

Syst Biol Reprod Med. 2017 Jun;63(3):179-191. doi: 10.1080/19396368.2017.1295332. Epub 2017 Mar 17.

PMID:
28306342
7.

Assessment of the Blood-Brain Barrier Permeability of Potential Neuroprotective Aurones in Parallel Artificial Membrane Permeability Assay and Porcine Brain Endothelial Cell Models.

Liew KF, Hanapi NA, Chan KL, Yusof SR, Lee CY.

J Pharm Sci. 2017 Feb;106(2):502-510. doi: 10.1016/j.xphs.2016.10.006. Epub 2016 Nov 14.

PMID:
27855959
8.

1HNMR-Based Discriminatory Analysis of Eurycoma longifolia from Different Locations and Establishing a Profile for Primary Metabolites Identification and Quassinoids Quantification.

Ebrahimi F, Ibrahim B, Teh CH, Murugaiyah V, Lam CK.

Planta Med. 2017 Jan;83(1-02):172-182. doi: 10.1055/s-0042-110857. Epub 2016 Jul 11.

PMID:
27399233
9.

Urinary NMR-based metabolomic analysis of rats possessing variable sperm count following orally administered Eurycoma longifolia extracts of different quassinoid levels.

Ebrahimi F, Ibrahim B, Teh CH, Murugaiyah V, Chan KL.

J Ethnopharmacol. 2016 Apr 22;182:80-9. doi: 10.1016/j.jep.2016.02.015. Epub 2016 Feb 16.

PMID:
26899442
10.

Flavonoids and phenylethanoid glycosides from Lippia nodiflora as promising antihyperuricemic agents and elucidation of their mechanism of action.

Cheng LC, Murugaiyah V, Chan KL.

J Ethnopharmacol. 2015 Dec 24;176:485-93. doi: 10.1016/j.jep.2015.11.025. Epub 2015 Nov 28.

PMID:
26593216
11.

Decreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract.

Chen Y, Phang WM, Mu AK, Chan CK, Low BS, Sasidharan S, Chan KL.

Front Pharmacol. 2015 Sep 23;6:211. doi: 10.3389/fphar.2015.00211. eCollection 2015.

13.

The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells.

Tong KL, Chan KL, AbuBakar S, Low BS, Ma HQ, Wong PF.

PLoS One. 2015 Mar 31;10(3):e0121752. doi: 10.1371/journal.pone.0121752. eCollection 2015.

14.

Blood-brain barrier permeable anticholinesterase aurones: synthesis, structure-activity relationship, and drug-like properties.

Liew KF, Chan KL, Lee CY.

Eur J Med Chem. 2015 Apr 13;94:195-210. doi: 10.1016/j.ejmech.2015.02.055. Epub 2015 Mar 2.

PMID:
25768702
15.

A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity.

Ikram NK, Durrant JD, Muchtaridi M, Zalaludin AS, Purwitasari N, Mohamed N, Rahim AS, Lam CK, Normi YM, Rahman NA, Amaro RE, Wahab HA.

J Chem Inf Model. 2015 Feb 23;55(2):308-16. doi: 10.1021/ci500405g. Epub 2015 Jan 29.

16.

Isocorilagin, a cholinesterase inhibitor from Phyllanthus niruri.

Koay YH, Basiri A, Murugaiyah V, Chan KL.

Nat Prod Commun. 2014 Apr;9(4):515-7.

PMID:
24868872
17.

Anti-tumor activity of Eurycoma longifolia root extracts against K-562 cell line: in vitro and in vivo study.

Al-Salahi OS, Ji D, Majid AM, Kit-Lam C, Abdullah WZ, Zaki A, Jamal Din SK, Yusoff NM, Majid AS.

PLoS One. 2014 Jan 7;9(1):e83818. doi: 10.1371/journal.pone.0083818. eCollection 2014.

18.
19.

Anti-angiogenic quassinoid-rich fraction from Eurycoma longifolia modulates endothelial cell function.

Al-Salahi OS, Kit-Lam C, Majid AM, Al-Suede FS, Mohammed Saghir SA, Abdullah WZ, Ahamed MB, Yusoff NM.

Microvasc Res. 2013 Nov;90:30-9. doi: 10.1016/j.mvr.2013.07.007. Epub 2013 Jul 27.

PMID:
23899415
20.

Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

Low BS, Choi SB, Abdul Wahab H, Das PK, Chan KL.

J Ethnopharmacol. 2013 Aug 26;149(1):201-7. doi: 10.1016/j.jep.2013.06.023. Epub 2013 Jun 27.

PMID:
23810842

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