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Items: 1 to 20 of 38

1.

α-Pyrone and Sterol Constituents of Penicillium aurantiacobrunneum, a Fungal Associate of the Lichen Niebla homalea.

Tan CY, Wang F, Anaya-Eugenio GD, Gallucci JC, Goughenour KD, Rappleye CA, Spjut RW, Carcache de Blanco EJ, Kinghorn AD, Rakotondraibe LH.

J Nat Prod. 2019 Aug 29. doi: 10.1021/acs.jnatprod.9b00340. [Epub ahead of print]

PMID:
31465222
2.

Histoplasma Responses to Nutritional Immunity Imposed by Macrophage Activation.

Brechting PJ, Rappleye CA.

J Fungi (Basel). 2019 Jun 5;5(2). pii: E45. doi: 10.3390/jof5020045. Review.

3.

Macrophage activation by IFN-γ triggers restriction of phagosomal copper from intracellular pathogens.

Shen Q, Beucler MJ, Ray SC, Rappleye CA.

PLoS Pathog. 2018 Nov 19;14(11):e1007444. doi: 10.1371/journal.ppat.1007444. eCollection 2018 Nov.

4.

Characterization of the APSES-family transcriptional regulators of Histoplasma capsulatum.

Longo LVG, Ray SC, Puccia R, Rappleye CA.

FEMS Yeast Res. 2018 Dec 1;18(8). doi: 10.1093/femsyr/foy087.

5.

Synthesis and biological evaluation of aminothiazoles against Histoplasma capsulatum and Cryptococcus neoformans.

Ishita K, Stefanopoulos S, Khalil A, Cheng X, Tjarks W, Rappleye CA.

Bioorg Med Chem. 2018 May 15;26(9):2251-2261. doi: 10.1016/j.bmc.2018.01.024. Epub 2018 Feb 2.

6.

Flying under the radar: Histoplasma capsulatum avoidance of innate immune recognition.

Ray SC, Rappleye CA.

Semin Cell Dev Biol. 2019 May;89:91-98. doi: 10.1016/j.semcdb.2018.03.009. Epub 2018 Mar 21. Review.

PMID:
29551572
7.

O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures.

Garfoot AL, Goughenour KD, Wüthrich M, Rajaram MVS, Schlesinger LS, Klein BS, Rappleye CA.

MBio. 2018 Jan 2;9(1). pii: e02121-17. doi: 10.1128/mBio.02121-17.

8.

Differentiation of the fungus Histoplasma capsulatum into a pathogen of phagocytes.

Shen Q, Rappleye CA.

Curr Opin Microbiol. 2017 Dec;40:1-7. doi: 10.1016/j.mib.2017.10.003. Epub 2017 Oct 27. Review.

9.

Eng1 and Exg8 Are the Major β-Glucanases Secreted by the Fungal Pathogen Histoplasma capsulatum.

Garfoot AL, Dearing KL, VanSchoiack AD, Wysocki VH, Rappleye CA.

J Biol Chem. 2017 Mar 24;292(12):4801-4810. doi: 10.1074/jbc.M116.762104. Epub 2017 Feb 2.

10.

Antifungal therapeutics for dimorphic fungal pathogens.

Goughenour KD, Rappleye CA.

Virulence. 2017 Feb 17;8(2):211-221. doi: 10.1080/21505594.2016.1235653. Epub 2016 Sep 19.

11.

Targeting CBLB as a potential therapeutic approach for disseminated candidiasis.

Xiao Y, Tang J, Guo H, Zhao Y, Tang R, Ouyang S, Zeng Q, Rappleye CA, Rajaram MV, Schlesinger LS, Tao L, Brown GD, Langdon WY, Li BT, Zhang J.

Nat Med. 2016 Aug;22(8):906-14. doi: 10.1038/nm.4141. Epub 2016 Jul 18.

12.

The Eng1 β-Glucanase Enhances Histoplasma Virulence by Reducing β-Glucan Exposure.

Garfoot AL, Shen Q, Wüthrich M, Klein BS, Rappleye CA.

MBio. 2016 Apr 19;7(2):e01388-15. doi: 10.1128/mBio.01388-15.

13.

Quantitative Microplate-Based Growth Assay for Determination of Antifungal Susceptibility of Histoplasma capsulatum Yeasts.

Goughenour KD, Balada-Llasat JM, Rappleye CA.

J Clin Microbiol. 2015 Oct;53(10):3286-95. doi: 10.1128/JCM.00795-15. Epub 2015 Aug 5.

14.

Histoplasma capsulatum surmounts obstacles to intracellular pathogenesis.

Garfoot AL, Rappleye CA.

FEBS J. 2016 Feb;283(4):619-33. doi: 10.1111/febs.13389. Epub 2015 Nov 25. Review.

15.

Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans.

Khalil A, Edwards JA, Rappleye CA, Tjarks W.

Bioorg Med Chem. 2015 Feb 1;23(3):532-47. doi: 10.1016/j.bmc.2014.12.006. Epub 2014 Dec 10.

16.

Transgenic expression of CXCR3 on T cells enhances susceptibility to cutaneous Leishmania major infection by inhibiting monocyte maturation and promoting a Th2 response.

Oghumu S, Stock JC, Varikuti S, Dong R, Terrazas C, Edwards JA, Rappleye CA, Holovatyk A, Sharpe A, Satoskar AR.

Infect Immun. 2015 Jan;83(1):67-76. doi: 10.1128/IAI.02540-14. Epub 2014 Oct 13.

17.

Glycosylation and immunoreactivity of the Histoplasma capsulatum Cfp4 yeast-phase exoantigen.

Holbrook ED, Kemski MM, Richer SM, Wheat LJ, Rappleye CA.

Infect Immun. 2014 Oct;82(10):4414-25. doi: 10.1128/IAI.01893-14. Epub 2014 Aug 11.

18.

Histoplasma capsulatum depends on de novo vitamin biosynthesis for intraphagosomal proliferation.

Garfoot AL, Zemska O, Rappleye CA.

Infect Immun. 2014 Jan;82(1):393-404. doi: 10.1128/IAI.00824-13. Epub 2013 Nov 4.

19.

Histoplasma yeast and mycelial transcriptomes reveal pathogenic-phase and lineage-specific gene expression profiles.

Edwards JA, Chen C, Kemski MM, Hu J, Mitchell TK, Rappleye CA.

BMC Genomics. 2013 Oct 10;14:695. doi: 10.1186/1471-2164-14-695.

20.

Identification of an aminothiazole with antifungal activity against intracellular Histoplasma capsulatum.

Edwards JA, Kemski MM, Rappleye CA.

Antimicrob Agents Chemother. 2013 Sep;57(9):4349-59. doi: 10.1128/AAC.00459-13. Epub 2013 Jul 1.

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