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Items: 20


Nanoparticle contrast-enhanced micro-CT: A preclinical tool for the 3D imaging of liver and spleen in longitudinal mouse studies.

Liu CN, Morin J, Dokmanovich M, Bluette CT, Goldstein R, Manickam B, Bagi CM.

J Pharmacol Toxicol Methods. 2019 Mar - Apr;96:67-77. doi: 10.1016/j.vascn.2019.02.003. Epub 2019 Feb 7.


Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic Assessments.

Gropp KE, Carlson CS, Evans MG, Bagi CM, Reagan WJ, Hurst SI, Shelton DL, Zorbas MA.

Toxicol Pathol. 2018 Jun;46(4):408-420. doi: 10.1177/0192623318772501. Epub 2018 May 16.


Metabolic Syndrome and Bone: Pharmacologically Induced Diabetes has Deleterious Effect on Bone in Growing Obese Rats.

Bagi CM, Edwards K, Berryman E.

Calcif Tissue Int. 2018 Jun;102(6):683-694. doi: 10.1007/s00223-017-0367-z. Epub 2017 Dec 1.


Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption.

Johnson K, Levine K, Sergi J, Chamoun J, Roach R, Vekich J, Favis M, Horn M, Cao X, Miller B, Snyder W, Aivazian D, Reagan W, Berryman E, Colangelo J, Markiewicz V, Bagi CM, Brown TP, Coyle A, Mohammadi M, Magram J.

J Bone Miner Res. 2017 Oct;32(10):2062-2073. doi: 10.1002/jbmr.3197. Epub 2017 Aug 25.


Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model.

LaBranche TP, Bendele AM, Omura BC, Gropp KE, Hurst SI, Bagi CM, Cummings TR, Grantham LE 2nd, Shelton DL, Zorbas MA.

Ann Rheum Dis. 2017 Jan;76(1):295-302. doi: 10.1136/annrheumdis-2015-208913. Epub 2016 Jul 5.


Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA.

Bagi CM, Berryman E, Zakur DE, Wilkie D, Andresen CJ.

Arthritis Res Ther. 2015 Nov 6;17:315. doi: 10.1186/s13075-015-0829-5.


Correlation between ╬╝CT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis.

Bagi CM, Zakur DE, Berryman E, Andresen CJ, Wilkie D.

J Transl Med. 2015 Aug 25;13:276. doi: 10.1186/s12967-015-0641-7.


Oral administration of soluble guanylate cyclase agonists to rats results in osteoclastic bone resorption and remodeling with new bone formation in the appendicular and axial skeleton.

Homer BL, Morton D, Bagi CM, Warneke JA, Andresen CJ, Whiteley LO, Morris DL, Tones MA.

Toxicol Pathol. 2015 Apr;43(3):411-23. doi: 10.1177/0192623314546559. Epub 2014 Aug 20.


The rational use of animal models in the evaluation of novel bone regenerative therapies.

Peric M, Dumic-Cule I, Grcevic D, Matijasic M, Verbanac D, Paul R, Grgurevic L, Trkulja V, Bagi CM, Vukicevic S.

Bone. 2015 Jan;70:73-86. doi: 10.1016/j.bone.2014.07.010. Epub 2014 Jul 13. Review.


Patient-derived xenografts reveal limits to PI3K/mTOR- and MEK-mediated inhibition of bladder cancer.

Cirone P, Andresen CJ, Eswaraka JR, Lappin PB, Bagi CM.

Cancer Chemother Pharmacol. 2014 Mar;73(3):525-38. doi: 10.1007/s00280-014-2376-1. Epub 2014 Jan 19.


Models of hepatocellular carcinoma and biomarker strategy.

Bagi CM, Andresen CJ.

Cancers (Basel). 2010 Jul 7;2(3):1441-52. doi: 10.3390/cancers2031441.


Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft model.

Bagi CM, Christensen J, Cohen DP, Roberts WG, Wilkie D, Swanson T, Tuthill T, Andresen CJ.

Cancer Biol Ther. 2009 May;8(9):856-65.


Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases.

Bagi CM, Roberts GW, Andresen CJ.

Cancer. 2008 May 15;112(10):2313-21. doi: 10.1002/cncr.23429.


Age-related changes in marmoset trabecular and cortical bone and response to alendronate therapy resemble human bone physiology and architecture.

Bagi CM, Volberg M, Moalli M, Shen V, Olson E, Hanson N, Berryman E, Andresen CJ.

Anat Rec (Hoboken). 2007 Aug;290(8):1005-16.


4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 3. Identification of lead candidate.

Wood J, Bagi CM, Akuche C, Bacchiocchi A, Baryza J, Blue ML, Brennan C, Campbell AM, Choi S, Cook JH, Conrad P, Dixon BR, Ehrlich PP, Gane T, Gunn D, Joe T, Johnson JS, Jordan J, Kramss R, Liu P, Levy J, Lowe DB, McAlexander I, Natero R, Redman AM, Scott WJ, Town C, Wang M, Wang Y, Zhang Z.

Bioorg Med Chem Lett. 2006 Sep 15;16(18):4965-8. Epub 2006 Jun 27.


The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: correlation with mechanical testing, pQCT and DXA.

Bagi CM, Hanson N, Andresen C, Pero R, Lariviere R, Turner CH, Laib A.

Bone. 2006 Jan;38(1):136-44. Epub 2005 Nov 18.


Targeting of therapeutic agents to bone to treat metastatic cancer.

Bagi CM.

Adv Drug Deliv Rev. 2005 May 25;57(7):995-1010. Epub 2005 Apr 13. Review.


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