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Items: 13

1.

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins.

Trezise S, Karnowski A, Fedele PL, Mithraprabhu S, Liao Y, D'Costa K, Kueh AJ, Hardy MP, Owczarek CM, Herold MJ, Spencer A, Shi W, Willis SN, Nutt SL, Corcoran LM.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2161. doi: 10.3390/ijms19082161.

2.

Role of the β Common (βc) Family of Cytokines in Health and Disease.

Hercus TR, Kan WLT, Broughton SE, Tvorogov D, Ramshaw HS, Sandow JJ, Nero TL, Dhagat U, Thompson EJ, Shing KSCT, McKenzie DR, Wilson NJ, Owczarek CM, Vairo G, Nash AD, Tergaonkar V, Hughes T, Ekert PG, Samuel MS, Bonder CS, Grimbaldeston MA, Parker MW, Lopez AF.

Cold Spring Harb Perspect Biol. 2018 Jun 1;10(6). pii: a028514. doi: 10.1101/cshperspect.a028514. Review.

PMID:
28716883
3.

An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry.

McCaffrey K, Boo I, Owczarek CM, Hardy MP, Perugini MA, Fabri L, Scotney P, Poumbourios P, Drummer HE.

J Virol. 2017 Feb 14;91(5). pii: e01668-16. doi: 10.1128/JVI.01668-16. Print 2017 Mar 1.

4.

CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors.

Panousis C, Dhagat U, Edwards KM, Rayzman V, Hardy MP, Braley H, Gauvreau GM, Hercus TR, Smith S, Sehmi R, McMillan L, Dottore M, McClure BJ, Fabri LJ, Vairo G, Lopez AF, Parker MW, Nash AD, Wilson NJ, Wilson MJ, Owczarek CM.

MAbs. 2016;8(3):436-53. doi: 10.1080/19420862.2015.1119352. Epub 2015 Dec 14.

5.

Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.

Broughton SE, Hercus TR, Hardy MP, McClure BJ, Nero TL, Dottore M, Huynh H, Braley H, Barry EF, Kan WL, Dhagat U, Scotney P, Hartman D, Busfield SJ, Owczarek CM, Nash AD, Wilson NJ, Parker MW, Lopez AF.

Cell Rep. 2014 Jul 24;8(2):410-9. doi: 10.1016/j.celrep.2014.06.038. Epub 2014 Jul 17.

6.

Identification of potent antagonist antibodies against mouse IL-13Rα1 using novel bioassays.

Edwards KM, Huynh H, Prasad R, McDonald A, Hardy MP, Scotney P, Owczarek CM, Busfield SJ, Panousis C, Wilson NJ.

J Immunol Methods. 2014 May;407:48-57. doi: 10.1016/j.jim.2014.03.019. Epub 2014 Apr 3.

PMID:
24704819
7.

Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock.

Samarajiwa SA, Mangan NE, Hardy MP, Najdovska M, Dubach D, Braniff SJ, Owczarek CM, Hertzog PJ.

J Immunol. 2014 May 1;192(9):4425-35. doi: 10.4049/jimmunol.1302388. Epub 2014 Apr 2.

8.

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.

Broughton SE, Hercus TR, Nero TL, Dhagat U, Owczarek CM, Hardy MP, Fabri LJ, Scotney PD, Nash AD, Wilson NJ, Lopez AF, Parker MW.

Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):358-61. doi: 10.1107/S2053230X14002593. Epub 2014 Feb 19.

9.

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE).

Munro KM, Dixon KJ, Gresle MM, Jonas A, Kemper D, Doherty W, Fabri LJ, Owczarek CM, Pearse M, Boyd AW, Kilpatrick TJ, Butzkueven H, Turnley AM.

PLoS One. 2013;8(2):e55948. doi: 10.1371/journal.pone.0055948. Epub 2013 Feb 4.

10.

Characterization of the type I interferon locus and identification of novel genes.

Hardy MP, Owczarek CM, Jermiin LS, Ejdebäck M, Hertzog PJ.

Genomics. 2004 Aug;84(2):331-45.

PMID:
15233997
11.
12.

Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster.

Hardy MP, Sanij EP, Hertzog PJ, Owczarek CM.

Mamm Genome. 2003 Feb;14(2):105-18.

PMID:
12584606
13.

Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression.

Hardy MP, Hertzog PJ, Owczarek CM.

Biochem J. 2002 Jul 15;365(Pt 2):355-67.

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