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Items: 20


Conserved associations between G-quadruplex-forming DNA motifs and virulence gene families in malaria parasites.

Gage HL, Merrick CJ.

BMC Genomics. 2020 Mar 17;21(1):236. doi: 10.1186/s12864-020-6625-x.


Parasitic Protozoa: Unusual Roles for G-Quadruplexes in Early-Diverging Eukaryotes.

Dumetz F, Merrick CJ.

Molecules. 2019 Apr 5;24(7). pii: E1339. doi: 10.3390/molecules24071339. Review.


RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics.

Claessens A, Harris LM, Stanojcic S, Chappell L, Stanton A, Kuk N, Veneziano-Broccia P, Sterkers Y, Rayner JC, Merrick CJ.

PLoS Genet. 2018 Jul 2;14(7):e1007490. doi: 10.1371/journal.pgen.1007490. eCollection 2018 Jul.


ATAC-ing Transcriptional Mysteries in Malaria Parasites.

Merrick CJ.

Cell Host Microbe. 2018 Apr 11;23(4):425-426. doi: 10.1016/j.chom.2018.03.016.


Checks and balances? DNA replication and the cell cycle in Plasmodium.

Matthews H, Duffy CW, Merrick CJ.

Parasit Vectors. 2018 Mar 27;11(1):216. doi: 10.1186/s13071-018-2800-1. Review.


G-Quadruplex DNA Motifs in the Malaria Parasite Plasmodium falciparum and Their Potential as Novel Antimalarial Drug Targets.

Harris LM, Monsell KR, Noulin F, Famodimu MT, Smargiasso N, Damblon C, Horrocks P, Merrick CJ.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01828-17. doi: 10.1128/AAC.01828-17. Print 2018 Mar.


G-Quadruplexes: Prediction, Characterization, and Biological Application.

Kwok CK, Merrick CJ.

Trends Biotechnol. 2017 Oct;35(10):997-1013. doi: 10.1016/j.tibtech.2017.06.012. Epub 2017 Jul 26. Review.


Single-molecule analysis reveals that DNA replication dynamics vary across the course of schizogony in the malaria parasite Plasmodium falciparum.

Stanojcic S, Kuk N, Ullah I, Sterkers Y, Merrick CJ.

Sci Rep. 2017 Jun 21;7(1):4003. doi: 10.1038/s41598-017-04407-z.


Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains.

Merrick CJ, Jiang RH, Skillman KM, Samarakoon U, Moore RM, Dzikowski R, Ferdig MT, Duraisingh MT.

PLoS One. 2015 Mar 17;10(3):e0118865. doi: 10.1371/journal.pone.0118865. eCollection 2015.


G-quadruplexes in pathogens: a common route to virulence control?

Harris LM, Merrick CJ.

PLoS Pathog. 2015 Feb 5;11(2):e1004562. doi: 10.1371/journal.ppat.1004562. eCollection 2015 Feb. Review.


A quantitative analysis of Plasmodium falciparum transfection using DNA-loaded erythrocytes.

Hasenkamp S, Merrick CJ, Horrocks P.

Mol Biochem Parasitol. 2013 Feb;187(2):117-20. doi: 10.1016/j.molbiopara.2013.01.001. Epub 2013 Jan 11.


Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria.

Merrick CJ, Huttenhower C, Buckee C, Amambua-Ngwa A, Gomez-Escobar N, Walther M, Conway DJ, Duraisingh MT.

J Infect Dis. 2012 May 15;205(10):1593-600. doi: 10.1093/infdis/jis239. Epub 2012 Mar 23.


Epigenetics in Plasmodium: what do we really know?

Merrick CJ, Duraisingh MT.

Eukaryot Cell. 2010 Aug;9(8):1150-8. doi: 10.1128/EC.00093-10. Epub 2010 Jun 18. Review.


The effect of Plasmodium falciparum Sir2a histone deacetylase on clonal and longitudinal variation in expression of the var family of virulence genes.

Merrick CJ, Dzikowski R, Imamura H, Chuang J, Deitsch K, Duraisingh MT.

Int J Parasitol. 2010 Jan;40(1):35-43. doi: 10.1016/j.ijpara.2009.06.012. Epub 2009 Aug 8.


Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity.

Merrick CJ, Duraisingh MT.

Eukaryot Cell. 2007 Nov;6(11):2081-91. Epub 2007 Sep 7.


Heterochromatin-mediated control of virulence gene expression.

Merrick CJ, Duraisingh MT.

Mol Microbiol. 2006 Nov;62(3):612-20. Review.


Functional analysis of Avr9/Cf-9 rapidly elicited genes identifies a protein kinase, ACIK1, that is essential for full Cf-9-dependent disease resistance in tomato.

Rowland O, Ludwig AA, Merrick CJ, Baillieul F, Tracy FE, Durrant WE, Fritz-Laylin L, Nekrasov V, Sjölander K, Yoshioka H, Jones JD.

Plant Cell. 2005 Jan;17(1):295-310. Epub 2004 Dec 14.


Visualization of altered replication dynamics after DNA damage in human cells.

Merrick CJ, Jackson D, Diffley JF.

J Biol Chem. 2004 May 7;279(19):20067-75. Epub 2004 Feb 23.

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