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Items: 1 to 20 of 58

1.

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing.

Hassan S, Purdie KJ, Wang J, Harwood CA, Proby CM, Pourreyron C, Mladkova N, Nagano A, Dhayade S, Athineos D, Caley M, Mannella V, Blyth K, Inman GJ, Leigh IM.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3428. doi: 10.3390/ijms20143428.

2.

Diagnosis and treatment of basal cell carcinoma: European consensus-based interdisciplinary guidelines.

Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, Bataille V, Marmol VD, Dummer R, Harwood CA, Hauschild A, Höller C, Haedersdal M, Malvehy J, Middleton MR, Morton CA, Nagore E, Stratigos AJ, Szeimies RM, Tagliaferri L, Trakatelli M, Zalaudek I, Eggermont A, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC).

Eur J Cancer. 2019 Sep;118:10-34. doi: 10.1016/j.ejca.2019.06.003. Epub 2019 Jul 6.

PMID:
31288208
3.

Management of Kaposi sarcoma after solid organ transplantation: A European retrospective study.

Delyon J, Rabate C, Euvrard S, Harwood CA, Proby C, Güleç AT, Seçkin D, Del Marmol V, Bouwes-Bavinck JN, Ferrándiz-Pulido C, Ocampo MA, Barete S, Legendre C, Francès C, Porcher R, Lebbe C; Skin Care in Organ Transplant Patients Europe (SCOPE) group.

J Am Acad Dermatol. 2019 Aug;81(2):448-455. doi: 10.1016/j.jaad.2019.03.028. Epub 2019 Mar 19.

PMID:
30902727
4.

Epigenetic Regulation of iASPP-p63 Feedback Loop in Cutaneous Squamous Cell Carcinoma.

Robinson DJ, Patel A, Purdie KJ, Wang J, Rizvi H, Hufbauer M, Ostano P, Akgül B, Chiorino G, Harwood CA, Bergamaschi D.

J Invest Dermatol. 2019 Aug;139(8):1658-1671.e8. doi: 10.1016/j.jid.2019.01.020. Epub 2019 Jan 30.

PMID:
30710576
5.

Keratinocyte Carcinomas: Current Concepts and Future Research Priorities.

Nagarajan P, Asgari MM, Green AC, Guhan SM, Arron ST, Proby CM, Rollison DE, Harwood CA, Toland AE.

Clin Cancer Res. 2019 Apr 15;25(8):2379-2391. doi: 10.1158/1078-0432.CCR-18-1122. Epub 2018 Dec 6. Review.

PMID:
30523023
6.

Aggressive Squamous Cell Carcinoma in Organ Transplant Recipients.

Lanz J, Bouwes Bavinck JN, Westhuis M, Quint KD, Harwood CA, Nasir S, Van-de-Velde V, Proby CM, Ferrándiz C, Genders RE, Del Marmol V, Forchetti G, Hafner J, Vital DG, Hofbauer GFL.

JAMA Dermatol. 2019 Jan 1;155(1):66-71. doi: 10.1001/jamadermatol.2018.4406.

PMID:
30516812
7.

The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.

Inman GJ, Wang J, Nagano A, Alexandrov LB, Purdie KJ, Taylor RG, Sherwood V, Thomson J, Hogan S, Spender LC, South AP, Stratton M, Chelala C, Harwood CA, Proby CM, Leigh IM.

Nat Commun. 2018 Sep 10;9(1):3667. doi: 10.1038/s41467-018-06027-1.

8.

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions.

Purdie KJ, Proby CM, Rizvi H, Griffin H, Doorbar J, Sommerlad M, Feltkamp MC, der Meijden EV, Inman GJ, South AP, Leigh IM, Harwood CA.

Front Microbiol. 2018 Aug 14;9:1806. doi: 10.3389/fmicb.2018.01806. eCollection 2018.

9.

Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma.

Rose AM, Spender LC, Stephen C, Mitchell A, Rickaby W, Bray S, Evans AT, Dayal J, Purdie KJ, Harwood CA, Proby CM, Leigh IM, Coates PJ, Inman GJ.

Oncotarget. 2018 Feb 22;9(18):14552-14566. doi: 10.18632/oncotarget.24545. eCollection 2018 Mar 6.

10.

A Novel Mechanism for Activation of GLI1 by Nuclear SMO That Escapes Anti-SMO Inhibitors.

Rahman MM, Hazan A, Selway JL, Herath DS, Harwood CA, Pirzado MS, Atkar R, Kelsell DP, Linton KJ, Philpott MP, Neill GW.

Cancer Res. 2018 May 15;78(10):2577-2588. doi: 10.1158/0008-5472.CAN-17-2897. Epub 2018 Feb 20.

11.

Genomic analysis of atypical fibroxanthoma.

Lai K, Harwood CA, Purdie KJ, Proby CM, Leigh IM, Ravi N, Mully TW, Brooks L, Sandoval PM, Rosenblum MD, Arron ST.

PLoS One. 2017 Nov 15;12(11):e0188272. doi: 10.1371/journal.pone.0188272. eCollection 2017.

12.

Human papillomavirus and posttransplantation cutaneous squamous cell carcinoma: A multicenter, prospective cohort study.

Bouwes Bavinck JN, Feltkamp MCW, Green AC, Fiocco M, Euvrard S, Harwood CA, Nasir S, Thomson J, Proby CM, Naldi L, Diphoorn JCD, Venturuzzo A, Tessari G, Nindl I, Sampogna F, Abeni D, Neale RE, Goeman JJ, Quint KD, Halk AB, Sneek C, Genders RE, de Koning MNC, Quint WGV, Wieland U, Weissenborn S, Waterboer T, Pawlita M, Pfister H; EPI-HPV-UV-CA group.

Am J Transplant. 2018 May;18(5):1220-1230. doi: 10.1111/ajt.14537. Epub 2017 Nov 22.

13.

Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas.

Janus JM, O'Shaughnessy RFL, Harwood CA, Maffucci T.

Cancers (Basel). 2017 Jul 11;9(7). pii: E86. doi: 10.3390/cancers9070086. Review.

14.

Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma.

Knatko EV, Praslicka B, Higgins M, Evans A, Purdie KJ, Harwood CA, Proby CM, Ooi A, Dinkova-Kostova AT.

Cancer Prev Res (Phila). 2017 Jan;10(1):67-75. doi: 10.1158/1940-6207.CAPR-16-0218. Epub 2016 Dec 6.

15.

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma.

Cammareri P, Rose AM, Vincent DF, Wang J, Nagano A, Libertini S, Ridgway RA, Athineos D, Coates PJ, McHugh A, Pourreyron C, Dayal JH, Larsson J, Weidlich S, Spender LC, Sapkota GP, Purdie KJ, Proby CM, Harwood CA, Leigh IM, Clevers H, Barker N, Karlsson S, Pritchard C, Marais R, Chelala C, South AP, Sansom OJ, Inman GJ.

Nat Commun. 2016 Aug 25;7:12493. doi: 10.1038/ncomms12493.

16.

CREBBP mutation in human cutaneous squamous cell carcinoma.

Watt SA, Purdie KJ, den Breems NY, Dimon M, Tucker S, Arron ST, McHugh A, Xue DJ, Dayal JH, Harwood CA, Leigh IM, Proby CM, South AP.

Exp Dermatol. 2016 Aug;25(8):650-1. doi: 10.1111/exd.13044. Epub 2016 Jun 30. No abstract available.

PMID:
27094574
17.

Constitutive Autophagy and Nucleophagy during Epidermal Differentiation.

Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RFL, Bergamaschi D.

J Invest Dermatol. 2016 Jul;136(7):1460-1470. doi: 10.1016/j.jid.2016.03.016. Epub 2016 Mar 25.

18.

HLA Immunogenotype Determines Persistent Human Papillomavirus Virus Infection in HIV-Infected Patients Receiving Antiretroviral Treatment.

Meys R, Purdie KJ, de Koning MN, Quint KD, Little AM, Baker F, Francis N, Asboe D, Hawkins D, Marsh SG, Harwood CA, Gotch FM, Bunker CB.

J Infect Dis. 2016 Jun 1;213(11):1717-24. doi: 10.1093/infdis/jiw038. Epub 2016 Feb 9.

PMID:
26908737
19.

Novel CARD11 Mutations in Human Cutaneous Squamous Cell Carcinoma Lead to Aberrant NF-κB Regulation.

Watt SA, Purdie KJ, den Breems NY, Dimon M, Arron ST, McHugh AT, Xue DJ, Dayal JH, Proby CM, Harwood CA, Leigh IM, South AP.

Am J Pathol. 2015 Sep;185(9):2354-63. doi: 10.1016/j.ajpath.2015.05.018. Epub 2015 Jul 26.

20.

The Promise of Genomics and the Development of Targeted Therapies for Cutaneous Squamous Cell Carcinoma.

Harwood CA, Proby CM, Inman GJ, Leigh IM.

Acta Derm Venereol. 2016 Jan;96(1):3-16. doi: 10.2340/00015555-2181. Review.

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