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Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation.

Zaminelli T, Magli E, Frecentese F, Lescano CH, Campos R, Saccone I, Corvino A, Di Vaio P, Giordano F, Luciano P, Fiorino F, Perissutti E, Santagada V, Severino B, Caliendo G, De Nucci G.

ChemistryOpen. 2019 Apr 8;8(4):464-475. doi: 10.1002/open.201900060. eCollection 2019 Apr.


Effect of Polyphenols From Campomanesia adamantium on Platelet Aggregation and Inhibition of Cyclooxygenases: Molecular Docking and in Vitro Analysis.

Lescano CH, Freitas de Lima F, Mendes-Silvério CB, Justo AFO, da Silva Baldivia D, Vieira CP, Sanjinez-Argandoña EJ, Cardoso CAL, Mónica FZ, Pires de Oliveira I.

Front Pharmacol. 2018 Jun 12;9:617. doi: 10.3389/fphar.2018.00617. eCollection 2018.


Activation of soluble guanylyl cyclase with inhibition of multidrug resistance protein inhibitor-4 (MRP4) as a new antiplatelet therapy.

Mendes-Silverio CB, Lescano CH, Zaminelli T, Sollon C, Anhê GF, Antunes E, Mónica FZ.

Biochem Pharmacol. 2018 Jun;152:165-173. doi: 10.1016/j.bcp.2018.03.028. Epub 2018 Mar 30.


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