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Items: 5

1.

A New Topical Eye Drop Containing LyeTxI-b, A Synthetic Peptide Designed from A Lycosa erithrognata Venom Toxin, Was Effective to Treat Resistant Bacterial Keratitis.

Silva CND, Silva FRD, Dourado LFN, Reis PVMD, Silva RO, Costa BLD, Nunes PS, Amaral FA, Santos VLD, de Lima ME, Silva Cunha Júnior AD.

Toxins (Basel). 2019 Apr 4;11(4). pii: E203. doi: 10.3390/toxins11040203.

2.

PnPP-19 Peptide Restores Erectile Function in Hypertensive and Diabetic Animals Through Intravenous and Topical Administration.

Nunes da Silva C, Nunes KP, De Marco Almeida F, Silva Costa FL, Borges PV, Lacativa P, Pimenta AMC, Elena de Lima M.

J Sex Med. 2019 Mar;16(3):365-374. doi: 10.1016/j.jsxm.2019.01.004. Epub 2019 Feb 14.

PMID:
30773502
3.

Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model.

Silva FRD, Paiva MRB, Dourado LFN, Silva RO, Silva CND, Costa BLD, Toledo CR, de Lima ME, Silva-Cunha AD.

J Venom Anim Toxins Incl Trop Dis. 2018 Nov 21;24:31. doi: 10.1186/s40409-018-0168-5. eCollection 2018.

4.

PnTx2-6 (or δ-CNTX-Pn2a), a toxin from Phoneutria nigriventer spider venom, releases l-glutamate from rat brain synaptosomes involving Na+ and Ca2+ channels and changes protein expression at the blood-brain barrier.

Silva CND, Lomeo RS, Torres FS, Borges MH, Nascimento MC, Rodrigues Mesquita-Britto MH, Rapôso C, Pimenta AMC, da Cruz-Höfling MA, Gomes DA, de Lima ME.

Toxicon. 2018 Aug;150:280-288. doi: 10.1016/j.toxicon.2018.06.073. Epub 2018 Jun 15.

PMID:
29913196
5.

Crotoxin from Crotalus durissus terrificus snake venom induces the release of glutamate from cerebrocortical synaptosomes via N and P/Q calcium channels.

Lomeo Rda S, Gonçalves AP, da Silva CN, de Paula AT, Costa Santos DO, Fortes-Dias CL, Gomes DA, de Lima ME.

Toxicon. 2014 Jul;85:5-16. doi: 10.1016/j.toxicon.2014.04.008. Epub 2014 Apr 19.

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