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Items: 1 to 20 of 69

1.

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R.

Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.

2.

Chromatin dynamics during liver regeneration.

Arechederra M, Berasain C, Avila MA, Fernández-Barrena MG.

Semin Cell Dev Biol. 2019 Apr 9. pii: S1084-9521(18)30193-9. doi: 10.1016/j.semcdb.2019.03.004. [Epub ahead of print] Review.

PMID:
30940574
3.

Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins.

Jiménez M, Urtasun R, Elizalde M, Azkona M, Latasa MU, Uriarte I, Arechederra M, Alignani D, Bárcena-Varela M, Álvarez-Sola G, Colyn L, Santamaría E, Sangro B, Rodriguez-Ortigosa C, Fernández-Barrena MG, Ávila MA, Berasain C.

Nucleic Acids Res. 2019 Apr 23;47(7):3450-3466. doi: 10.1093/nar/gkz014.

4.

Targeting CCL2/CCR2 in Tumor-Infiltrating Macrophages: A Tool Emerging Out of the Box Against Hepatocellular Carcinoma.

Avila MA, Berasain C.

Cell Mol Gastroenterol Hepatol. 2019;7(2):293-294. doi: 10.1016/j.jcmgh.2018.11.002. Epub 2018 Dec 4. No abstract available.

5.

Splicing alterations contributing to cancer hallmarks in the liver: central role of dedifferentiation and genome instability.

Jimenez M, Arechederra M, Ávila MA, Berasain C.

Transl Gastroenterol Hepatol. 2018 Oct 31;3:84. doi: 10.21037/tgh.2018.10.11. eCollection 2018. Review.

6.

The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis.

Santamaría E, Rodríguez-Ortigosa CM, Uriarte I, Latasa MU, Urtasun R, Alvarez-Sola G, Bárcena-Varela M, Colyn L, Arcelus S, Jiménez M, Deutschmann K, Peleteiro-Vigil A, Gómez-Cambronero J, Milkiewicz M, Milkiewicz P, Sangro B, Keitel V, Monte MJ, Marin JJG, Fernández-Barrena MG, Ávila MA, Berasain C.

Hepatology. 2019 Apr;69(4):1632-1647. doi: 10.1002/hep.30348. Epub 2019 Mar 4.

PMID:
30411380
7.

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis.

Fernández-Ramos D, Fernández-Tussy P, Lopitz-Otsoa F, Gutiérrez-de-Juan V, Navasa N, Barbier-Torres L, Zubiete-Franco I, Simón J, Fernández AF, Arbelaiz A, Aransay AM, Lavín JL, Beraza N, Perugorria MJ, Banales JM, Villa E, Fraga MF, Anguita J, Avila MA, Berasain C, Iruzibieta P, Crespo J, Lu SC, Varela-Rey M, Mato JM, Delgado TC, Martínez-Chantar ML.

Cell Death Dis. 2018 Sep 20;9(10):958. doi: 10.1038/s41419-018-1014-y.

8.

Fibroblast growth factors 19 and 21 in acute liver damage.

Shan Z, Alvarez-Sola G, Uriarte I, Arechederra M, Fernández-Barrena MG, Berasain C, Ju C, Avila MA.

Ann Transl Med. 2018 Jun;6(12):257. doi: 10.21037/atm.2018.05.26. Review.

9.

Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma.

Bárcena-Varela M, Caruso S, Llerena S, Álvarez-Sola G, Uriarte I, Latasa MU, Urtasun R, Rebouissou S, Alvarez L, Jimenez M, Santamaría E, Rodriguez-Ortigosa C, Mazza G, Rombouts K, San José-Eneriz E, Rabal O, Agirre X, Iraburu M, Santos-Laso A, Banales JM, Zucman-Rossi J, Prósper F, Oyarzabal J, Berasain C, Ávila MA, Fernández-Barrena MG.

Hepatology. 2019 Feb;69(2):587-603. doi: 10.1002/hep.30168. Epub 2019 Jan 4.

PMID:
30014490
10.

LKB1: Controlling Quiescence and Genomic Integrity at Home.

Berasain C, Ávila MA.

Trends Endocrinol Metab. 2018 Oct;29(10):668-670. doi: 10.1016/j.tem.2018.03.017. Epub 2018 Apr 5.

PMID:
29628399
11.

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice.

Alvarez-Sola G, Uriarte I, Latasa MU, Jimenez M, Barcena-Varela M, Santamaría E, Urtasun R, Rodriguez-Ortigosa C, Prieto J, Corrales FJ, Baulies A, García-Ruiz C, Fernandez-Checa JC, Berraondo P, Fernandez-Barrena MG, Berasain C, Avila MA.

Cell Death Dis. 2017 Oct 5;8(10):e3083. doi: 10.1038/cddis.2017.480.

12.

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications.

Alvarez-Sola G, Uriarte I, Latasa MU, Jimenez M, Barcena-Varela M, Santamaría E, Urtasun R, Rodriguez-Ortigosa C, Prieto J, Berraondo P, Fernandez-Barrena MG, Berasain C, Avila MA.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1326-1334. doi: 10.1016/j.bbadis.2017.06.025. Epub 2017 Jul 12. Review.

13.

Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis.

Alvarez-Sola G, Uriarte I, Latasa MU, Urtasun R, Bárcena-Varela M, Elizalde M, Jiménez M, Rodriguez-Ortigosa CM, Corrales FJ, Fernández-Barrena MG, Berasain C, Avila MA.

Dig Dis. 2017;35(3):158-165. doi: 10.1159/000450905. Epub 2017 Mar 1. Review.

PMID:
28249259
14.

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration.

Alvarez-Sola G, Uriarte I, Latasa MU, Fernandez-Barrena MG, Urtasun R, Elizalde M, Barcena-Varela M, Jiménez M, Chang HC, Barbero R, Catalán V, Rodríguez A, Frühbeck G, Gallego-Escuredo JM, Gavaldà-Navarro A, Villarroya F, Rodriguez-Ortigosa CM, Corrales FJ, Prieto J, Berraondo P, Berasain C, Avila MA.

Gut. 2017 Oct;66(10):1818-1828. doi: 10.1136/gutjnl-2016-312975. Epub 2017 Jan 24.

PMID:
28119353
15.

Targeting the correct target in HCC.

Berasain C, Lechel A.

Gut. 2017 Aug;66(8):1352-1354. doi: 10.1136/gutjnl-2016-313462. Epub 2017 Jan 18. No abstract available.

PMID:
28100646
16.

ACOX2 deficiency: An inborn error of bile acid synthesis identified in an adolescent with persistent hypertransaminasemia.

Monte MJ, Alonso-Peña M, Briz O, Herraez E, Berasain C, Argemi J, Prieto J, Marin JJG.

J Hepatol. 2017 Mar;66(3):581-588. doi: 10.1016/j.jhep.2016.11.005. Epub 2016 Nov 21.

PMID:
27884763
17.

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.

Simile MM, Latte G, Demartis MI, Brozzetti S, Calvisi DF, Porcu A, Feo CF, Seddaiu MA, Daino L, Berasain C, Tomasi ML, Avila MA, Feo F, Pascale RM.

Oncotarget. 2016 Aug 2;7(31):49194-49216. doi: 10.18632/oncotarget.10246.

18.

New molecular interactions of c-Myc in cholangiocarcinoma may open new therapeutic opportunities.

Berasain C, Fernández-Barrena MG, Avila MA.

Hepatology. 2016 Aug;64(2):336-9. doi: 10.1002/hep.28607. Epub 2016 May 28. No abstract available.

PMID:
27102840
19.

Further evidence on the janus-faced nature of the epidermal growth factor receptor: From liver regeneration to hepatocarcinogenesis.

Berasain C, Avila MA.

Hepatology. 2016 Feb;63(2):371-4. doi: 10.1002/hep.28246. Epub 2015 Dec 9. No abstract available.

PMID:
26403097
20.

Regulation of hepatocyte identity and quiescence.

Berasain C, Avila MA.

Cell Mol Life Sci. 2015 Oct;72(20):3831-51. doi: 10.1007/s00018-015-1970-7. Epub 2015 Jun 19. Review.

PMID:
26089250

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