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Items: 1 to 20 of 52


Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation.

Pasquinucci L, Turnaturi R, Montenegro L, Caraci F, Chiechio S, Parenti C.

Eur J Pharmacol. 2019 Jan 25;847:97-102. doi: 10.1016/j.ejphar.2019.01.031. [Epub ahead of print]


Tumor necrosis factor-related apoptosis-inducing ligand reduces the expression of the neuroprotective Na+ /Ca2+ exchanger isoform NCX3 in human neuroblastoma SH-SY5Y cells.

Di Benedetto G, Valerio O, Lariccia V, Burgaletto C, Lempereur L, Parenti C, Zanghì GN, Matteucci A, Amoroso S, Bernardini R, Cantarella G.

FEBS J. 2018 Dec 15. doi: 10.1111/febs.14732. [Epub ahead of print]


Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review.

Turnaturi R, Montenegro L, Marrazzo A, Parenti R, Pasquinucci L, Parenti C.

Eur J Med Chem. 2018 Jul 15;155:492-502. doi: 10.1016/j.ejmech.2018.06.017. Epub 2018 Jun 7. Review.


Synthesis and Structure-Activity Relationships of (-)-cis-N-Normetazocine-Based LP1 Derivatives.

Pasquinucci L, Parenti C, Amata E, Georgoussi Z, Pallaki P, Camarda V, Calò G, Arena E, Montenegro L, Turnaturi R.

Pharmaceuticals (Basel). 2018 May 5;11(2). pii: E40. doi: 10.3390/ph11020040.


Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists.

Turnaturi R, Parenti C, Prezzavento O, Marrazzo A, Pallaki P, Georgoussi Z, Amata E, Pasquinucci L.

Molecules. 2018 Mar 16;23(3). pii: E677. doi: 10.3390/molecules23030677.


In Vitro Evaluation of Sunscreen Safety: Effects of the Vehicle and Repeated Applications on Skin Permeation from Topical Formulations.

Montenegro L, Turnaturi R, Parenti C, Pasquinucci L.

Pharmaceutics. 2018 Feb 27;10(1). pii: E27. doi: 10.3390/pharmaceutics10010027.


Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review.

Turnaturi R, Marrazzo A, Parenti C, Pasquinucci L.

Eur J Med Chem. 2018 Mar 25;148:410-422. doi: 10.1016/j.ejmech.2018.02.046. Epub 2018 Feb 17. Review.


Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy.

Montenegro L, Turnaturi R, Parenti C, Pasquinucci L.

Nanomaterials (Basel). 2018 Feb 5;8(2). pii: E87. doi: 10.3390/nano8020087. Review.


Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets.

Vicario N, Zappalà A, Calabrese G, Gulino R, Parenti C, Gulisano M, Parenti R.

Front Physiol. 2017 Dec 18;8:1060. doi: 10.3389/fphys.2017.01060. eCollection 2017. Review.


Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.

Montenegro L, Parenti C, Turnaturi R, Pasquinucci L.

Pharmaceutics. 2017 Dec 10;9(4). pii: E58. doi: 10.3390/pharmaceutics9040058.


Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?

Arena E, Dichiara M, Floresta G, Parenti C, Marrazzo A, Pittalà V, Amata E, Prezzavento O.

Future Med Chem. 2018 Jan;10(2):231-256. doi: 10.4155/fmc-2017-0164. Epub 2017 Nov 29. Review.


Chronic Treatment with Fluoxetine Induces Sex-Dependent Analgesic Effects and Modulates HDAC2 and mGlu2 Expression in Female Mice.

Zammataro M, Merlo S, Barresi M, Parenti C, Hu H, Sortino MA, Chiechio S.

Front Pharmacol. 2017 Oct 20;8:743. doi: 10.3389/fphar.2017.00743. eCollection 2017.


Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles.

Montenegro L, Pasquinucci L, Zappalà A, Chiechio S, Turnaturi R, Parenti C.

Pharmaceutics. 2017 Oct 21;9(4). pii: E48. doi: 10.3390/pharmaceutics9040048.


Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

Dichiara M, Amata E, Rescifina A, Prezzavento O, Floresta G, Parenti C, Pittalà V, Marrazzo A.

Future Med Chem. 2017 Oct;9(15):1749-1764. doi: 10.4155/fmc-2017-0064. Epub 2017 Sep 4. Review.


Development of novel LP1-based analogues with enhanced delta opioid receptor profile.

Pasquinucci L, Turnaturi R, Prezzavento O, Arena E, Aricò G, Georgoussi Z, Parenti R, Cantarella G, Parenti C.

Bioorg Med Chem. 2017 Sep 1;25(17):4745-4752. doi: 10.1016/j.bmc.2017.07.021. Epub 2017 Jul 11.


Sigma-2 receptor ligands QSAR model dataset.

Rescifina A, Floresta G, Marrazzo A, Parenti C, Prezzavento O, Nastasi G, Dichiara M, Amata E.

Data Brief. 2017 Jun 16;13:514-535. doi: 10.1016/j.dib.2017.06.022. eCollection 2017 Aug.


Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.

Amata E, Pittalà V, Marrazzo A, Parenti C, Prezzavento O, Arena E, Nabavi SM, Salerno L.

Clin Sci (Lond). 2017 Jun 30;131(14):1701-1712. doi: 10.1042/CS20170157. Print 2017 Jul 15. Review.


Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

Rescifina A, Floresta G, Marrazzo A, Parenti C, Prezzavento O, Nastasi G, Dichiara M, Amata E.

Eur J Pharm Sci. 2017 Aug 30;106:94-101. doi: 10.1016/j.ejps.2017.05.061. Epub 2017 May 29.


Inhibition of Cx43 mediates protective effects on hypoxic/reoxygenated human neuroblastoma cells.

Vicario N, Calabrese G, Zappalà A, Parenti C, Forte S, Graziano ACE, Vanella L, Pellitteri R, Cardile V, Parenti R.

J Cell Mol Med. 2017 Oct;21(10):2563-2572. doi: 10.1111/jcmm.13177. Epub 2017 May 9.


Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation.

Graziano AC, Cardile V, Avola R, Vicario N, Parenti C, Salvatorelli L, Magro G, Parenti R.

Oncotarget. 2017 Feb 21;8(8):13917-13931. doi: 10.18632/oncotarget.14715.

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