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Items: 20

1.

Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer.

Jiang W, Meng L, Xu G, Lv C, Wang H, Tian H, Chen R, Jiao B, Wang B, Huang C.

Oncol Lett. 2018 Nov;16(5):6445-6457. doi: 10.3892/ol.2018.9486. Epub 2018 Sep 24.

2.

High expression of AKR1C1 is associated with proliferation and migration of small-cell lung cancer cells.

Tian H, Li X, Jiang W, Lv C, Sun W, Huang C, Chen R.

Lung Cancer (Auckl). 2016 May 2;7:53-61. doi: 10.2147/LCTT.S90694. eCollection 2016.

3.

Syntaxin 1A mediates isoflurane but not hypoxia preconditioning-induced alleviation of hypoxia-reoxygenation injury in rat cardiomyocytes.

Liu M, Zhang H, Zhang Q, Huang C, Shi X.

Am J Transl Res. 2015 Oct 15;7(10):1883-95. eCollection 2015.

4.

Ophiobolin O isolated from Aspergillus ustus induces G1 arrest of MCF-7 cells through interaction with AKT/GSK3β/cyclin D1 signaling.

Lv C, Qin W, Zhu T, Wei S, Hong K, Zhu W, Chen R, Huang C.

Mar Drugs. 2015 Jan 16;13(1):431-43. doi: 10.3390/md13010431.

5.

Ophiobolin-O reverses adriamycin resistance via cell cycle arrest and apoptosis sensitization in adriamycin-resistant human breast carcinoma (MCF-7/ADR) cells.

Sun W, Lv C, Zhu T, Yang X, Wei S, Sun J, Hong K, Zhu W, Huang C.

Mar Drugs. 2013 Nov 14;11(11):4570-84. doi: 10.3390/md11114570.

7.

Wentilactone B from Aspergillus wentii induces apoptosis and inhibits proliferation and migration of human hepatoma SMMC-7721 cells.

Zhang Z, Miao L, Sun W, Jiao B, Wang B, Yao L, Huang C.

Biol Pharm Bull. 2012;35(11):1964-71. Epub 2012 Aug 27.

8.

SD118-xanthocillin X (1), a novel marine agent extracted from Penicillium commune, induces autophagy through the inhibition of the MEK/ERK pathway.

Zhao Y, Chen H, Shang Z, Jiao B, Yuan B, Sun W, Wang B, Miao M, Huang C.

Mar Drugs. 2012 Jun;10(6):1345-59. doi: 10.3390/md10061345. Epub 2012 Jun 11.

9.

Spiroindimicins A-D: new bisindole alkaloids from a deep-sea-derived actinomycete.

Zhang W, Liu Z, Li S, Yang T, Zhang Q, Ma L, Tian X, Zhang H, Huang C, Zhang S, Ju J, Shen Y, Zhang C.

Org Lett. 2012 Jul 6;14(13):3364-7. doi: 10.1021/ol301343n. Epub 2012 Jun 13.

PMID:
22694269
10.

Cytotoxic angucycline class glycosides from the deep sea actinomycete Streptomyces lusitanus SCSIO LR32.

Huang H, Yang T, Ren X, Liu J, Song Y, Sun A, Ma J, Wang B, Zhang Y, Huang C, Zhang C, Ju J.

J Nat Prod. 2012 Feb 24;75(2):202-8. doi: 10.1021/np2008335. Epub 2012 Feb 3.

PMID:
22304344
11.

ERK1/2 and Akt pathway activated during (3R,6R)-bassiatin(1)-induced apoptosis in MCF-7 cells.

Meng L, Tao H, Dong G, Yang T, Zhang W, Zhu W, Huang C.

Cell Biol Int. 2012 Apr 1;36(4):345-8. doi: 10.1042/CBI20110388.

PMID:
22150072
12.

The novel agent ophiobolin O induces apoptosis and cell cycle arrest of MCF-7 cells through activation of MAPK signaling pathways.

Yang T, Lu Z, Meng L, Wei S, Hong K, Zhu W, Huang C.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):579-85. doi: 10.1016/j.bmcl.2011.10.079. Epub 2011 Oct 31.

PMID:
22130129
13.

Antimalarial β-carboline and indolactam alkaloids from Marinactinospora thermotolerans, a deep sea isolate.

Huang H, Yao Y, He Z, Yang T, Ma J, Tian X, Li Y, Huang C, Chen X, Li W, Zhang S, Zhang C, Ju J.

J Nat Prod. 2011 Oct 28;74(10):2122-7. doi: 10.1021/np200399t. Epub 2011 Oct 6.

PMID:
21977916
14.

Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Zhao Q, Guo Y, Feng B, Li L, Huang C, Jiao B.

Fitoterapia. 2011 Jul;82(5):735-41. doi: 10.1016/j.fitote.2011.03.004. Epub 2011 Mar 31.

PMID:
21459134
15.

A novel antioestrogen agent (3R,6R)-bassiatin inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression in 17β-oestradiol-treated MCF-7 cells.

Meng L, Feng B, Tao H, Yang T, Meng Y, Zhu W, Huang C.

Cell Biol Int. 2011 Jun;35(6):599-605. doi: 10.1042/CBI20100765.

PMID:
21241249
16.

Marinactinones A-C, new γ-pyrones from marine actinomycete Marinactinospora thermotolerans SCSIO 00606.

Wang F, Tian X, Huang C, Li Q, Zhang S.

J Antibiot (Tokyo). 2011 Feb;64(2):189-92. doi: 10.1038/ja.2010.153. Epub 2010 Dec 15.

PMID:
21157453
17.

Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks.

Lu Z, Jia Q, Wang R, Wu X, Wu Y, Huang C, Li Y.

Phytomedicine. 2011 Feb 15;18(4):298-302. doi: 10.1016/j.phymed.2010.08.008. Epub 2010 Sep 18.

PMID:
20851586
18.

Targeted knockout of the mouse betaB2-crystallin gene (Crybb2) induces age-related cataract.

Zhang J, Li J, Huang C, Xue L, Peng Y, Fu Q, Gao L, Zhang J, Li W.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5476-83. doi: 10.1167/iovs.08-2179. Epub 2008 Aug 21.

PMID:
18719080
19.

Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats.

Liu X, Chen R, Shang Y, Jiao B, Huang C.

Chem Biol Interact. 2008 Nov 25;176(2-3):137-42. doi: 10.1016/j.cbi.2008.07.003. Epub 2008 Jul 23.

PMID:
18694741
20.

Superoxide radicals scavenging and xanthine oxidase inhibitory activity of magnesium lithospermate B from Salvia miltiorrhiza.

Liu X, Chen R, Shang Y, Jiao B, Huang C.

J Enzyme Inhib Med Chem. 2009 Jun;24(3):663-8. doi: 10.1080/14756360802323829.

PMID:
18686136

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