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Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling.

Kim HK, Jeon J, Song IS, Heo HJ, Jeong SH, Long LT, Thu VT, Ko TH, Kim M, Kim N, Lee SR, Yang JS, Kang MS, Ahn JM, Cho JY, Ko KS, Rhee BD, Nilius B, Ha NC, Shimizu I, Minamino T, Cho KI, Park YS, Kim S, Han J.

Biochim Biophys Acta Mol Basis Dis. 2019 Aug 2. pii: S0925-4439(19)30241-8. doi: 10.1016/j.bbadis.2019.07.018. [Epub ahead of print]


Aerobic Exercise Training Decreases Hepatic Asprosin in Diabetic Rats.

Ko JR, Seo DY, Kim TN, Park SH, Kwak HB, Ko KS, Rhee BD, Han J.

J Clin Med. 2019 May 12;8(5). pii: E666. doi: 10.3390/jcm8050666.


The direct effect of lobeglitazone, a new thiazolidinedione, on pancreatic beta cells: A comparison with other thiazolidinediones.

Kwon MJ, Lee YJ, Jung HS, Shin HM, Kim TN, Lee SH, Rhee BD, Kim MK, Park JH.

Diabetes Res Clin Pract. 2019 May;151:209-223. doi: 10.1016/j.diabres.2019.04.006. Epub 2019 Apr 4.


High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone.

Kim D, Ahn BN, Kim Y, Hur DY, Yang JW, Park GB, Jang JE, Lee EJ, Kwon MJ, Kim TN, Kim MK, Park JH, Rhee BD, Lee SH.

J Diabetes Res. 2019 Jan 9;2019:2376512. doi: 10.1155/2019/2376512. eCollection 2019.


Cyclic stretch increases mitochondrial biogenesis in a cardiac cell line.

Kim HK, Kang YG, Jeong SH, Park N, Marquez J, Ko KS, Rhee BD, Shin JW, Han J.

Biochem Biophys Res Commun. 2018 Nov 2;505(3):768-774. doi: 10.1016/j.bbrc.2018.10.003. Epub 2018 Oct 5.


Hemodynamics in diabetic human aorta using computational fluid dynamics.

Shin E, Kim JJ, Lee S, Ko KS, Rhee BD, Han J, Kim N.

PLoS One. 2018 Aug 23;13(8):e0202671. doi: 10.1371/journal.pone.0202671. eCollection 2018.


Pharmacologic inhibition of AKT leads to cell death in relapsed multiple myeloma.

Song IS, Jeong YJ, Jeong SH, Kim HK, Ha NC, Shin M, Ko KS, Rhee BD, Shim S, Jang SW, Han J.

Cancer Lett. 2018 Sep 28;432:205-215. doi: 10.1016/j.canlet.2018.06.020. Epub 2018 Jun 19.


A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells.

Kim HK, Cho SW, Heo HJ, Jeong SH, Kim M, Ko KS, Rhee BD, Mishchenko NP, Vasileva EA, Fedoreyev SA, Stonik VA, Han J.

Mar Drugs. 2018 Jun 2;16(6). pii: E192. doi: 10.3390/md16060192.


Aerobic exercise training decreases cereblon and increases AMPK signaling in the skeletal muscle of STZ-induced diabetic rats.

Ko JR, Seo DY, Park SH, Kwak HB, Kim M, Ko KS, Rhee BD, Han J.

Biochem Biophys Res Commun. 2018 Jun 22;501(2):448-453. doi: 10.1016/j.bbrc.2018.05.009. Epub 2018 May 10.


Ursolic acid in health and disease.

Seo DY, Lee SR, Heo JW, No MH, Rhee BD, Ko KS, Kwak HB, Han J.

Korean J Physiol Pharmacol. 2018 May;22(3):235-248. doi: 10.4196/kjpp.2018.22.3.235. Epub 2018 Apr 25. Review.


Exercise training causes a partial improvement through increasing testosterone and eNOS for erectile function in middle-aged rats.

Seo DY, Lee SR, Kwak HB, Park H, Seo KW, Noh YH, Song KM, Ryu JK, Ko KS, Rhee BD, Han J.

Exp Gerontol. 2018 Jul 15;108:131-138. doi: 10.1016/j.exger.2018.04.003. Epub 2018 Apr 5.


Alternative splicing isoforms in health and disease.

Kim HK, Pham MHC, Ko KS, Rhee BD, Han J.

Pflugers Arch. 2018 Jul;470(7):995-1016. doi: 10.1007/s00424-018-2136-x. Epub 2018 Mar 13. Review.


Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts.

Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J.

Pflugers Arch. 2018 Feb;470(2):263-275. doi: 10.1007/s00424-017-2076-x. Epub 2017 Oct 14.


Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins.

Ha SH, Kim HK, Anh NTT, Kim N, Ko KS, Rhee BD, Han J.

Korean J Physiol Pharmacol. 2017 Sep;21(5):531-546. doi: 10.4196/kjpp.2017.21.5.531. Epub 2017 Aug 22.


Kallmann syndrome with a Tyr113His PROKR2 mutation.

Ha JH, Lee S, Kim Y, Moon JI, Seo J, Jang JH, Cho EH, Kim JM, Rhee BD, Ko KS, Yoo SJ, Won JC.

Medicine (Baltimore). 2017 Sep;96(35):e7974. doi: 10.1097/MD.0000000000007974.


Comparison of pancreatic beta cells and alpha cells under hyperglycemia: Inverse coupling in pAkt-FoxO1.

Kim MK, Shin HM, Jung H, Lee E, Kim TK, Kim TN, Kwon MJ, Lee SH, Rhee BD, Park JH.

Diabetes Res Clin Pract. 2017 Sep;131:1-11. doi: 10.1016/j.diabres.2017.05.017. Epub 2017 May 19.


Current and upcoming mitochondrial targets for cancer therapy.

Kim HK, Noh YH, Nilius B, Ko KS, Rhee BD, Kim N, Han J.

Semin Cancer Biol. 2017 Dec;47:154-167. doi: 10.1016/j.semcancer.2017.06.006. Epub 2017 Jun 13. Review.


Age-related changes in skeletal muscle mitochondria: the role of exercise.

Seo DY, Lee SR, Kim N, Ko KS, Rhee BD, Han J.

Integr Med Res. 2016 Sep;5(3):182-186. doi: 10.1016/j.imr.2016.07.003. Epub 2016 Jul 22. Review.


Mitochondrial DNA, mitochondrial dysfunction, and cardiac manifestations.

Lee SR, Kim N, Noh YH, Xu Z, Ko KS, Rhee BD, Han J.

Front Biosci (Landmark Ed). 2017 Mar 1;22:1177-1194. Review.

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