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Items: 8


Dealing with frequent hitters in drug discovery: a multidisciplinary view on the issue of filtering compounds on biological screenings.

Dantas RF, Evangelista TCS, Neves BJ, Senger MR, Andrade CH, Ferreira SB, Silva-Junior FP.

Expert Opin Drug Discov. 2019 Aug 16:1-14. doi: 10.1080/17460441.2019.1654453. [Epub ahead of print]


Flavonoids from Brazilian Cerrado: Biosynthesis, Chemical and Biological Profile.

Peixoto JC, Neves BJ, Vasconcelos FG, Napolitano HB, Barbalho MGDS, Silva SDE, Rosseto LP.

Molecules. 2019 Aug 9;24(16). pii: E2891. doi: 10.3390/molecules24162891. Review.


Drug Repurposing for Paracoccidioidomycosis Through a Computational Chemogenomics Framework.

de Oliveira AA, Neves BJ, Silva LDC, Soares CMA, Andrade CH, Pereira M.

Front Microbiol. 2019 Jun 12;10:1301. doi: 10.3389/fmicb.2019.01301. eCollection 2019.


Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study.

Ferreira DD, Mesquita JT, da Costa Silva TA, Romanelli MM, da Gama Jaen Batista D, da Silva CF, da Gama ANS, Neves BJ, Melo-Filho CC, Correia Soeiro MN, Andrade CH, Tempone AG.

J Venom Anim Toxins Incl Trop Dis. 2018 Oct 30;24:30. doi: 10.1186/s40409-018-0165-8. eCollection 2018.


Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds.

Rogerio KR, Carvalho LJM, Domingues LHP, Neves BJ, Moreira Filho JT, Castro RN, Bianco Júnior C, Daniel-Ribeiro CT, Andrade CH, Graebin CS.

Mem Inst Oswaldo Cruz. 2018;113(8):e170452. doi: 10.1590/0074-02760170452. Epub 2018 Jun 18.


In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases.

Andrade CH, Neves BJ, Melo-Filho CC, Rodrigues J, Silva DC, Braga RC, Cravo PVL.

Curr Med Chem. 2018 Mar 8. doi: 10.2174/0929867325666180309114824. [Epub ahead of print]


Modern approaches to accelerate discovery of new antischistosomal drugs.

Neves BJ, Muratov E, Machado RB, Andrade CH, Cravo PV.

Expert Opin Drug Discov. 2016 Jun;11(6):557-67. doi: 10.1080/17460441.2016.1178230. Epub 2016 May 3. Review.


Blocking the L-type Ca2+ channel (Cav 1.2) is the key mechanism for the vascular relaxing effect of Pterodon spp. and its isolated diterpene methyl-6α-acetoxy-7β-hydroxyvouacapan-17β-oate.

de Fátima Reis C, de Andrade DM, Junior Neves B, de Almeida Ribeiro Oliveira L, Pinho JF, da Silva LP, Dos Santos Cruz J, Bara MT, Andrade CH, Rocha ML.

Pharmacol Res. 2015 Oct;100:242-9. doi: 10.1016/j.phrs.2015.08.007. Epub 2015 Aug 17.


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