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Items: 1 to 20 of 128

1.

The Role of Lipids and Membranes in the Pathogenesis of Alzheimer's Disease: A Comprehensive View.

Penke B, Paragi G, Gera J, Berkecz R, Kovács Z, Crul T, Vígh L.

Curr Alzheimer Res. 2018 Sep 11. doi: 10.2174/1567205015666180911151716. [Epub ahead of print]

PMID:
30207230
2.

Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions.

Penke B, Bogár F, Crul T, Sántha M, Tóth ME, Vígh L.

Int J Mol Sci. 2018 Jan 22;19(1). pii: E325. doi: 10.3390/ijms19010325. Review.

3.

Studies for Improving a Rat Model of Alzheimer's Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory.

Kasza Á, Penke B, Frank Z, Bozsó Z, Szegedi V, Hunya Á, Németh K, Kozma G, Fülöp L.

Molecules. 2017 Nov 18;22(11). pii: E2007. doi: 10.3390/molecules22112007.

4.

β-Amyloid and the Pathomechanisms of Alzheimer's Disease: A Comprehensive View.

Penke B, Bogár F, Fülöp L.

Molecules. 2017 Oct 10;22(10). pii: E1692. doi: 10.3390/molecules22101692. Review.

5.

The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases.

Penke B, Fulop L, Szucs M, Frecska E.

Curr Neuropharmacol. 2018;16(1):97-116. doi: 10.2174/1570159X15666170529104323. Review.

6.

Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease.

Kasza Á, Hunya Á, Frank Z, Fülöp F, Török Z, Balogh G, Sántha M, Bálind Á, Bernáth S, Blundell KL, Prodromou C, Horváth I, Zeiler HJ, Hooper PL, Vigh L, Penke B.

J Alzheimers Dis. 2016 May 7;53(2):557-71. doi: 10.3233/JAD-150860.

7.

Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.

Völgyi K, Háden K, Kis V, Gulyássy P, Badics K, Györffy BA, Simor A, Szabó Z, Janáky T, Drahos L, Dobolyi Á, Penke B, Juhász G, Kékesi KA.

Mol Neurobiol. 2017 Apr;54(3):2060-2078. doi: 10.1007/s12035-015-9682-4. Epub 2016 Feb 24.

PMID:
26910821
8.

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design.

Gutierrez LJ, Angelina E, Gyebrovszki A, Fülöp L, Peruchena N, Baldoni HA, Penke B, Enriz RD.

J Biomol Struct Dyn. 2017 Feb;35(2):413-426. doi: 10.1080/07391102.2016.1145143. Epub 2016 Mar 8.

PMID:
26813690
9.

Protein Folding and Misfolding, Endoplasmic Reticulum Stress in Neurodegenerative Diseases: in Trace of Novel Drug Targets.

Penke B, Bogár F, Fülöp L.

Curr Protein Pept Sci. 2016;17(2):169-82. Review.

PMID:
26521955
10.

Dysfunction of Endoplasmic Reticulum (ER) and Mitochondria (MT) in Alzheimer's Disease: The Role of the ER-MT Cross-Talk.

Volgyi K, Juhász G, Kovacs Z, Penke B.

Curr Alzheimer Res. 2015;12(7):655-72. Review.

PMID:
26159206
11.

Acute intracerebral treatment with amyloid-beta (1-42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats.

Kalweit AN, Yang H, Colitti-Klausnitzer J, Fülöp L, Bozsó Z, Penke B, Manahan-Vaughan D.

Front Behav Neurosci. 2015 May 6;9:103. doi: 10.3389/fnbeh.2015.00103. eCollection 2015.

12.

Structural and nanomechanical comparison of epitaxially and solution-grown amyloid β25-35 fibrils.

Murvai Ü, Somkuti J, Smeller L, Penke B, Kellermayer MS.

Biochim Biophys Acta. 2015 May;1854(5):327-32. doi: 10.1016/j.bbapap.2015.01.003. Epub 2015 Jan 17.

PMID:
25600136
13.

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse.

Varga E, Juhász G, Bozsó Z, Penke B, Fülöp L, Szegedi V.

J Alzheimers Dis. 2015;45(2):449-56. doi: 10.3233/JAD-142367.

PMID:
25547631
14.

Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors.

Varga E, Juhász G, Bozsó Z, Penke B, Fülöp L, Szegedi V.

Neural Plast. 2014;2014:584314. doi: 10.1155/2014/584314. Epub 2014 Sep 3.

15.

Simultaneous changes of spatial memory and spine density after intrahippocampal administration of fibrillar aβ1-42 to the rat brain.

Borbély E, Horváth J, Furdan S, Bozsó Z, Penke B, Fülöp L.

Biomed Res Int. 2014;2014:345305. doi: 10.1155/2014/345305. Epub 2014 Jun 23.

16.

Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array.

May C, Nordhoff E, Casjens S, Turewicz M, Eisenacher M, Gold R, Brüning T, Pesch B, Stephan C, Woitalla D, Penke B, Janáky T, Virók D, Siklós L, Engelhardt JI, Meyer HE.

PLoS One. 2014 Feb 26;9(2):e89596. doi: 10.1371/journal.pone.0089596. eCollection 2014.

17.

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition.

Koivisto H, Grimm MO, Rothhaar TL, Berkecz R, Lütjohann D D, Giniatullina R, Takalo M, Miettinen PO, Lahtinen HM, Giniatullin R, Penke B, Janáky T, Broersen LM, Hartmann T, Tanila H.

J Nutr Biochem. 2014 Feb;25(2):157-69. doi: 10.1016/j.jnutbio.2013.09.015. Epub 2013 Nov 6.

PMID:
24445040
18.

Epitaxial assembly dynamics of mutant amyloid β25-35_N27C fibrils explored with time-resolved scanning force microscopy.

Kellermayer MS, Murvai Ü, Horváth A, Lászlóffi E, Soós K, Penke B.

Biophys Chem. 2013 Dec 31;184:54-61. doi: 10.1016/j.bpc.2013.08.007. Epub 2013 Sep 5.

PMID:
24061043
19.

Tenascin-C deficiency ameliorates Alzheimer's disease-related pathology in mice.

Xie K, Liu Y, Hao W, Walter S, Penke B, Hartmann T, Schachner M, Fassbender K.

Neurobiol Aging. 2013 Oct;34(10):2389-98. doi: 10.1016/j.neurobiolaging.2013.04.013. Epub 2013 May 11.

PMID:
23673309
20.

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit.

Veszelka S, Tóth AE, Walter FR, Datki Z, Mózes E, Fülöp L, Bozsó Z, Hellinger E, Vastag M, Orsolits B, Környei Z, Penke B, Deli MA.

J Alzheimers Dis. 2013;36(3):487-501. doi: 10.3233/JAD-120163.

PMID:
23645098

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