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Items: 15

1.

Development of a new CiPA-compliant MOA in vitro assay on stem cell-derived cardiomyocytes including automated data analysis and model parameter optimization.

Mann S, Heide J, Airini R, Epureanu F, Deftu A, Deftu AT, Radu BM, Knott T, Amuzescu B.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.020. Epub 2019 Oct 17. No abstract available.

PMID:
31963081
2.

Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes.

Airini R, Iordache F, Alexandru D, Savu L, Epureanu FB, Mihailescu D, Amuzescu B, Maniu H.

J Cell Mol Med. 2019 Nov;23(11):7233-7245. doi: 10.1111/jcmm.14495. Epub 2019 Sep 3.

3.

Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp.

Mann SA, Heide J, Knott T, Airini R, Epureanu FB, Deftu AF, Deftu AT, Radu BM, Amuzescu B.

J Pharmacol Toxicol Methods. 2019 Nov - Dec;100:106599. doi: 10.1016/j.vascn.2019.106599. Epub 2019 Jun 20.

PMID:
31228558
4.

Electrophysiology, immunophenotype, and gene expression characterization of senescent and cryopreserved human amniotic fluid stem cells.

Iordache F, Constantinescu A, Andrei E, Amuzescu B, Halitzchi F, Savu L, Maniu H.

J Physiol Sci. 2016 Nov;66(6):463-476. Epub 2016 Apr 6.

PMID:
27053101
5.

Late cardiac sodium current can be assessed using automated patch-clamp.

Chevalier M, Amuzescu B, Gawali V, Todt H, Knott T, Scheel O, Abriel H.

F1000Res. 2014 Oct 16;3:245. doi: 10.12688/f1000research.5544.1. eCollection 2014.

6.

Action potential characterization of human induced pluripotent stem cell-derived cardiomyocytes using automated patch-clamp technology.

Scheel O, Frech S, Amuzescu B, Eisfeld J, Lin KH, Knott T.

Assay Drug Dev Technol. 2014 Oct;12(8):457-69. doi: 10.1089/adt.2014.601. Epub 2014 Oct 29.

PMID:
25353059
7.

Design, fabrication and characterization of a low-impedance 3D electrode array system for neuro-electrophysiology.

Kusko M, Craciunoiu F, Amuzescu B, Halitzchi F, Selescu T, Radoi A, Popescu M, Simion M, Bragaru A, Ignat T.

Sensors (Basel). 2012 Dec 3;12(12):16571-90. doi: 10.3390/s121216571.

8.

Stability and sustained oscillations in a ventricular cardiomyocyte model.

Amuzescu B, Georgescu A, Nistor G, Popescu M, Svab I, Flonta ML, Corlan AD.

Interdiscip Sci. 2012 Mar;4(1):1-18. doi: 10.1007/s12539-012-0116-y. Epub 2012 Mar 6.

PMID:
22392272
9.

ASIC1a activation by amitriptyline and FMRF-amide is removed by serine proteases.

Marin AN, Prica CM, Amuzescu BP, Neaga EI, Flonta ML.

Channels (Austin). 2008 Nov-Dec;2(6):419-28. Epub 2008 Nov 2.

PMID:
18927513
10.

Thermodynamic properties of hyperpolarization-activated current (Ih) in a subgroup of primary sensory neurons.

Pena F, Amuzescu B, Neaga E, Flonta ML.

Exp Brain Res. 2006 Aug;173(2):282-90. Epub 2006 May 5.

PMID:
16676167
11.

Extracellular trypsin increases ASIC1a selectivity for monovalent versus divalent cations.

Neaga E, Amuzescu B, Dinu C, Macri B, Pena F, Flonta ML.

J Neurosci Methods. 2005 Jun 15;144(2):241-8. Epub 2004 Dec 19.

PMID:
15910984
12.

Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation.

Gwanyanya A, Amuzescu B, Zakharov SI, Macianskiene R, Sipido KR, Bolotina VM, Vereecke J, Mubagwa K.

J Physiol. 2004 Sep 15;559(Pt 3):761-76. Epub 2004 Jul 22.

13.

Zinc is a voltage-dependent blocker of native and heterologously expressed epithelial Na+ channels.

Amuzescu B, Segal A, Flonta ML, Simaels J, Van Driessche W.

Pflugers Arch. 2003 Apr;446(1):69-77. Epub 2003 Feb 12.

PMID:
12690465
14.

Amitriptyline has a dual effect on the conductive properties of the epithelial Na channel.

Pena F, Neaga E, Amuzescu B, Nitu A, Flonta ML.

J Pharm Pharmacol. 2002 Oct;54(10):1393-8.

PMID:
12396302
15.

Cooling inhibits capsaicin-induced currents in cultured rat dorsal root ganglion neurones.

Babes A, Amuzescu B, Krause U, Scholz A, Flonta ML, Reid G.

Neurosci Lett. 2002 Jan 14;317(3):131-4.

PMID:
11755257

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