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Items: 1 to 20 of 56

1.

Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris.

Agamia NF, Hussein OM, Abdelmaksoud RE, Abdalla DM, Talaat IM, Zaki EI, El Tawdy A, Melnik BC.

Exp Dermatol. 2018 Sep 21. doi: 10.1111/exd.13787. [Epub ahead of print]

PMID:
30240097
2.

Activated mTORC1 signaling: The common driving force of type 2 diabetes and hidradenitis suppurativa.

De Vita V, Melnik BC.

J Am Acad Dermatol. 2018 May;78(5):e121. doi: 10.1016/j.jaad.2017.11.061. No abstract available.

PMID:
29678383
3.

Activation of mechanistic target of rapamycin complex 1: the common link between rheumatoid arthritis and diabetes mellitus.

De Vita V, Melnik BC.

Rheumatology (Oxford). 2018 Mar 7. doi: 10.1093/rheumatology/key038. [Epub ahead of print] No abstract available.

PMID:
29522125
4.

The Magnitude of mTORC1 Signalling May Predict the Response to Isotretinoin Treatment in Patients with Hidradenitis Suppurativa.

De Vita V, Melnik BC.

Dermatology. 2017;233(5):399-400. doi: 10.1159/000484408. Epub 2017 Dec 20. No abstract available.

5.

Acne vulgaris: The metabolic syndrome of the pilosebaceous follicle.

Melnik BC.

Clin Dermatol. 2018 Jan - Feb;36(1):29-40. doi: 10.1016/j.clindermatol.2017.09.006. Epub 2017 Sep 8. Review.

PMID:
29241749
6.

MicroRNAs: Milk's epigenetic regulators.

Melnik BC, Schmitz G.

Best Pract Res Clin Endocrinol Metab. 2017 Aug;31(4):427-442. doi: 10.1016/j.beem.2017.10.003. Epub 2017 Oct 20. Review.

PMID:
29221571
7.

Milk's Role as an Epigenetic Regulator in Health and Disease.

Melnik BC, Schmitz G.

Diseases. 2017 Mar 15;5(1). pii: E12. doi: 10.3390/diseases5010012. Review.

8.

p53: key conductor of all anti-acne therapies.

Melnik BC.

J Transl Med. 2017 Sep 19;15(1):195. doi: 10.1186/s12967-017-1297-2. Review.

9.

Overexpression of p53 explains isotretinoin's teratogenicity.

Melnik BC.

Exp Dermatol. 2018 Jan;27(1):91-93. doi: 10.1111/exd.13420. Epub 2017 Nov 7.

PMID:
28833556
10.

Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer.

Melnik BC.

Nutr Metab (Lond). 2017 Aug 15;14:55. doi: 10.1186/s12986-017-0212-4. eCollection 2017.

11.

Olumacostat Glasaretil, a Promising Topical Sebum-Suppressing Agent that Affects All Major Pathogenic Factors of Acne Vulgaris.

Melnik BC.

J Invest Dermatol. 2017 Jul;137(7):1405-1408. doi: 10.1016/j.jid.2017.01.026. Review.

12.

Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity.

Melnik BC.

Acta Derm Venereol. 2017 Feb 8;97(2):173-181. doi: 10.2340/00015555-2535. Review.

13.

The TRAIL to acne pathogenesis: let's focus on death pathways.

Melnik BC.

Exp Dermatol. 2017 Mar;26(3):270-272. doi: 10.1111/exd.13169. Epub 2016 Dec 9.

PMID:
27541445
14.

Milk: An epigenetic inducer of FoxP3 expression.

Melnik BC, John SM, Schmitz G.

J Allergy Clin Immunol. 2016 Sep;138(3):937-938. doi: 10.1016/j.jaci.2016.04.039. Epub 2016 Jul 12. No abstract available.

PMID:
27417024
15.

Milk miRNAs: simple nutrients or systemic functional regulators?

Melnik BC, Kakulas F, Geddes DT, Hartmann PE, John SM, Carrera-Bastos P, Cordain L, Schmitz G.

Nutr Metab (Lond). 2016 Jun 21;13:42. doi: 10.1186/s12986-016-0101-2. eCollection 2016.

16.

Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation.

Melnik BC, John SM, Carrera-Bastos P, Schmitz G.

Clin Transl Allergy. 2016 May 12;6:18. doi: 10.1186/s13601-016-0108-9. eCollection 2016. Review.

17.

Pro-inflammatory sebocyte growth and survival signalling in acne vulgaris are reversed by pro-apoptotic isotretinoin signalling.

Melnik BC.

Exp Dermatol. 2016 Sep;25(9):676-7. doi: 10.1111/exd.13032. No abstract available.

PMID:
27095186
18.

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases.

Melnik BC.

J Transl Med. 2015 Dec 21;13:385. doi: 10.1186/s12967-015-0746-z. Review.

19.

Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris?

Melnik BC.

Exp Dermatol. 2016 Mar;25(3):181-2. doi: 10.1111/exd.12917. Epub 2016 Feb 10. No abstract available.

PMID:
26660941
20.

Western diet-induced imbalances of FoxO1 and mTORC1 signalling promote the sebofollicular inflammasomopathy acne vulgaris.

Melnik BC.

Exp Dermatol. 2016 Feb;25(2):103-4. doi: 10.1111/exd.12898. Epub 2016 Jan 12. No abstract available.

PMID:
26567085

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