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Items: 1 to 20 of 67

1.

New Lanthanide Tag for the Generation of Pseudocontact Shifts in DNA by Site-Specific Ligation to a Phosphorothioate Group.

Wu Z, Lee MD, Carruthers TJ, Szabo M, Dennis ML, Swarbrick JD, Graham B, Otting G.

Bioconjug Chem. 2017 Jun 21;28(6):1741-1748. doi: 10.1021/acs.bioconjchem.7b00202. Epub 2017 May 15.

PMID:
28485576
2.

Studies of Carbon Monoxide Release from Ruthenium(II) Bipyridine Carbonyl Complexes upon UV-Light Exposure.

Kubeil M, Vernooij RR, Kubeil C, Wood BR, Graham B, Stephan H, Spiccia L.

Inorg Chem. 2017 May 15;56(10):5941-5952. doi: 10.1021/acs.inorgchem.7b00599. Epub 2017 May 3.

PMID:
28467070
3.

Structure restraints from heteronuclear pseudocontact shifts generated by lanthanide tags at two different sites.

Pearce BJG, Jabar S, Loh CT, Szabo M, Graham B, Otting G.

J Biomol NMR. 2017 May;68(1):19-32. doi: 10.1007/s10858-017-0111-z. Epub 2017 Apr 22.

PMID:
28434103
4.

A luminogenic lanthanide-based probe for the highly selective detection of nanomolar sulfide levels in aqueous samples.

Aulsebrook ML, Biswas S, Leaver FM, Grace MR, Graham B, Barrios AM, Tuck KL.

Chem Commun (Camb). 2017 May 2;53(36):4911-4914. doi: 10.1039/c7cc01764b.

PMID:
28361130
5.

Solution conformations of a linked construct of the Zika virus NS2B-NS3 protease.

Mahawaththa MC, Pearce BJG, Szabo M, Graham B, Klein CD, Nitsche C, Otting G.

Antiviral Res. 2017 Jun;142:141-147. doi: 10.1016/j.antiviral.2017.03.011. Epub 2017 Mar 21.

PMID:
28336347
6.

Investigation of Donor-Acceptor Stenhouse Adducts as New Visible Wavelength-Responsive Switching Elements for Lipid-Based Liquid Crystalline Systems.

Jia S, Du JD, Hawley A, Fong WK, Graham B, Boyd BJ.

Langmuir. 2017 Mar 7;33(9):2215-2221. doi: 10.1021/acs.langmuir.6b03726. Epub 2017 Feb 20.

PMID:
28099807
7.

Sequence-specific assignment of methyl groups from the neuronal SNARE complex using lanthanide-induced pseudocontact shifts.

Pan YZ, Quade B, Brewer KD, Szabo M, Swarbrick JD, Graham B, Rizo J.

J Biomol NMR. 2016 Dec;66(4):281-293. doi: 10.1007/s10858-016-0078-1. Epub 2016 Dec 17.

8.

Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation.

Edgington-Mitchell LE, Barlow N, Aurelio L, Samha A, Szabo M, Graham B, Bunnett N.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):254-260. doi: 10.1016/j.bmcl.2016.11.064. Epub 2016 Nov 25.

PMID:
27923620
9.

Legumain is activated in macrophages during pancreatitis.

Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, Storz P, Halangk W, Bogyo M, Bunnett NW.

Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G548-60. doi: 10.1152/ajpgi.00047.2016. Epub 2016 Aug 11.

PMID:
27514475
10.

Comprehensive Vibrational Spectroscopic Investigation of trans,trans,trans-[Pt(N3)2(OH)2(py)2], a Pt(IV) Diazido Anticancer Prodrug Candidate.

Vernooij RR, Joshi T, Shaili E, Kubeil M, Appadoo DR, Izgorodina EI, Graham B, Sadler PJ, Wood BR, Spiccia L.

Inorg Chem. 2016 Jun 20;55(12):5983-92. doi: 10.1021/acs.inorgchem.6b00476. Epub 2016 Jun 3.

11.

Enantiomeric two-armed lanthanide-binding tags for complementary effects in paramagnetic NMR spectroscopy.

Lee MD, Dennis ML, Swarbrick JD, Graham B.

Chem Commun (Camb). 2016 Jun 28;52(51):7954-7. doi: 10.1039/c6cc02325h. Epub 2016 Jun 2.

PMID:
27250640
12.

Overcoming artificial broadening in Gd(3+)-Gd(3+) distance distributions arising from dipolar pseudo-secular terms in DEER experiments.

Cohen MR, Frydman V, Milko P, Iron MA, Abdelkader EH, Lee MD, Swarbrick JD, Raitsimring A, Otting G, Graham B, Feintuch A, Goldfarb D.

Phys Chem Chem Phys. 2016 May 14;18(18):12847-59. doi: 10.1039/c6cp00829a. Epub 2016 Apr 22.

PMID:
27102158
13.

Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets.

Chen WN, Nitsche C, Pilla KB, Graham B, Huber T, Klein CD, Otting G.

J Am Chem Soc. 2016 Apr 6;138(13):4539-46. doi: 10.1021/jacs.6b00416. Epub 2016 Mar 24.

PMID:
26974502
14.

Cellular Uptake and Photo-Cytotoxicity of a Gadolinium(III)-DOTA-Naphthalimide Complex "Clicked" to a Lipidated Tat Peptide.

O'Malley WI, Rubbiani R, Aulsebrook ML, Grace MR, Spiccia L, Tuck KL, Gasser G, Graham B.

Molecules. 2016 Feb 5;21(2). pii: E194. doi: 10.3390/molecules21020194.

15.

Luminescent Alkyne-Bearing Terbium(III) Complexes and Their Application to Bioorthogonal Protein Labeling.

O'Malley WI, Abdelkader EH, Aulsebrook ML, Rubbiani R, Loh CT, Grace MR, Spiccia L, Gasser G, Otting G, Tuck KL, Graham B.

Inorg Chem. 2016 Feb 15;55(4):1674-82. doi: 10.1021/acs.inorgchem.5b02605. Epub 2016 Jan 28.

PMID:
26821062
16.

Neomycin B-cyclen conjugates and their Zn(II) complexes as RNA-binding agents.

Kong B, Joshi T, Belousoff MJ, Tor Y, Graham B, Spiccia L.

J Inorg Biochem. 2016 Sep;162:334-342. doi: 10.1016/j.jinorgbio.2015.11.029. Epub 2015 Dec 31.

PMID:
26786595
17.

Installation of a Rigid EDTA-Like Motif into a Protein α-Helix for Paramagnetic NMR Spectroscopy with Cobalt(II) Ions.

Swarbrick JD, Ung P, Dennis ML, Lee MD, Chhabra S, Graham B.

Chemistry. 2016 Jan 22;22(4):1228-32. doi: 10.1002/chem.201503139. Epub 2015 Dec 17.

PMID:
26634335
18.

Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.

Schembri LS, Stoddart LA, Briddon SJ, Kellam B, Canals M, Graham B, Scammells PJ.

J Med Chem. 2015 Dec 24;58(24):9754-67. doi: 10.1021/acs.jmedchem.5b01664. Epub 2015 Dec 16.

PMID:
26632862
19.

A New Gd(3+) Spin Label for Gd(3+)-Gd(3+) Distance Measurements in Proteins Produces Narrow Distance Distributions.

Abdelkader EH, Lee MD, Feintuch A, Cohen MR, Swarbrick JD, Otting G, Graham B, Goldfarb D.

J Phys Chem Lett. 2015 Dec 17;6(24):5016-21. doi: 10.1021/acs.jpclett.5b02451. Epub 2015 Dec 7.

PMID:
26623480
20.

Pulse EPR-enabled interpretation of scarce pseudocontact shifts induced by lanthanide binding tags.

Abdelkader EH, Yao X, Feintuch A, Adams LA, Aurelio L, Graham B, Goldfarb D, Otting G.

J Biomol NMR. 2016 Jan;64(1):39-51. doi: 10.1007/s10858-015-0003-z. Epub 2015 Nov 23.

PMID:
26597990

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