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Items: 7

1.

Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.

Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD.

Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0.

2.

PET Imaging of Microglial Activation-Beyond Targeting TSPO.

Janssen B, Vugts DJ, Windhorst AD, Mach RH.

Molecules. 2018 Mar 8;23(3). pii: E607. doi: 10.3390/molecules23030607. Review.

3.

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis.

Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE.

J Neuroinflammation. 2017 Dec 22;14(1):259. doi: 10.1186/s12974-017-1034-z.

4.

Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist.

Wilkinson SM, Barron ML, O'Brien-Brown J, Janssen B, Stokes L, Werry EL, Chishty M, Skarratt KK, Ong JA, Hibbs DE, Vugts DJ, Fuller S, Windhorst AD, Kassiou M.

ACS Chem Neurosci. 2017 Nov 15;8(11):2374-2380. doi: 10.1021/acschemneuro.7b00272. Epub 2017 Aug 25.

PMID:
28841278
5.

Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography.

Janssen B, Vugts DJ, Funke U, Molenaar GT, Kruijer PS, van Berckel BN, Lammertsma AA, Windhorst AD.

Biochim Biophys Acta. 2016 Mar;1862(3):425-41. doi: 10.1016/j.bbadis.2015.11.011. Epub 2015 Nov 28.

6.

Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [¹¹C]A-740003 as a novel tracer of neuroinflammation.

Janssen B, Vugts DJ, Funke U, Spaans A, Schuit RC, Kooijman E, Rongen M, Perk LR, Lammertsma AA, Windhorst AD.

J Labelled Comp Radiopharm. 2014 Jun 30;57(8):509-16. doi: 10.1002/jlcr.3206. Epub 2014 Jul 3.

PMID:
24995673
7.

(11) C-labeled and (18) F-labeled PET ligands for subtype-specific imaging of histamine receptors in the brain.

Funke U, Vugts DJ, Janssen B, Spaans A, Kruijer PS, Lammertsma AA, Perk LR, Windhorst AD.

J Labelled Comp Radiopharm. 2013 Mar-Apr;56(3-4):120-9. doi: 10.1002/jlcr.3038. Review.

PMID:
24285318

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