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Items: 1 to 20 of 64

1.

Chemical and Biological Aspects of Garcinol and Isogarcinol: Recent Developments.

Schobert R, Biersack B.

Chem Biodivers. 2019 Aug 6. doi: 10.1002/cbdv.201900366. [Epub ahead of print]

PMID:
31386266
2.

A new 4-(pyridinyl)-4H-benzo[g]chromene-5,10-dione ruthenium(II) complex inducing senescence in 518A2 melanoma cells.

Gold M, Mujahid Y, Ahmed K, Kostrhunova H, Kasparkova J, Brabec V, Biersack B, Schobert R.

J Biol Inorg Chem. 2019 Aug;24(5):647-657. doi: 10.1007/s00775-019-01677-y. Epub 2019 Jun 19.

PMID:
31218441
3.

Discovery of natural products with metal-binding properties as promising antibacterial agents.

Dandawate P, Padhye S, Schobert R, Biersack B.

Expert Opin Drug Discov. 2019 Jun;14(6):563-576. doi: 10.1080/17460441.2019.1593367. Epub 2019 Mar 25.

PMID:
30905202
4.

Interplay of non-coding RNAs and approved antimetabolites such as gemcitabine and pemetrexed in mesothelioma.

Biersack B.

Noncoding RNA Res. 2018 Nov 4;3(4):213-225. doi: 10.1016/j.ncrna.2018.11.001. eCollection 2018 Dec. Review.

5.

Relations between approved platinum drugs and non-coding RNAs in mesothelioma.

Biersack B.

Noncoding RNA Res. 2018 Aug 30;3(4):161-173. doi: 10.1016/j.ncrna.2018.08.001. eCollection 2018 Dec. Review.

6.

Anticancer properties of a new non-oxido vanadium(IV) complex with a catechol-modified 3,3'-diindolylmethane ligand.

Dankhoff K, Ahmad A, Weber B, Biersack B, Schobert R.

J Inorg Biochem. 2019 May;194:1-6. doi: 10.1016/j.jinorgbio.2019.02.005. Epub 2019 Feb 13.

PMID:
30784705
7.

Differential Methylation and Acetylation as the Epigenetic Basis of Resveratrol's Anticancer Activity.

Farhan M, Ullah MF, Faisal M, Farooqi AA, Sabitaliyevich UY, Biersack B, Ahmad A.

Medicines (Basel). 2019 Feb 13;6(1). pii: E24. doi: 10.3390/medicines6010024. Review.

8.

Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs.

Farhan M, Malik A, Ullah MF, Afaq S, Faisal M, Farooqi AA, Biersack B, Schobert R, Ahmad A.

Int J Mol Sci. 2019 Feb 13;20(4). pii: E800. doi: 10.3390/ijms20040800.

9.

Pentafluorophenyl Substitution of Natural Di(indol-3-yl)methane Strongly Enhances Growth Inhibition and Apoptosis Induction in Various Cancer Cell Lines.

Ahmad A, Dandawate P, Schruefer S, Padhye S, Sarkar FH, Schobert R, Biersack B.

Chem Biodivers. 2019 Apr;16(4):e1900028. doi: 10.1002/cbdv.201900028. Epub 2019 Mar 19.

PMID:
30715794
10.

Oxazole-Bridged Combretastatin A-4 Derivatives with Tethered Hydroxamic Acids: Structure⁻Activity Relations of New Inhibitors of HDAC and/or Tubulin Function.

Schmitt F, Gosch LC, Dittmer A, Rothemund M, Mueller T, Schobert R, Biersack B, Volkamer A, Höpfner M.

Int J Mol Sci. 2019 Jan 17;20(2). pii: E383. doi: 10.3390/ijms20020383.

11.

New naphthopyran analogues of LY290181 as potential tumor vascular-disrupting agents.

Schmitt F, Gold M, Rothemund M, Andronache I, Biersack B, Schobert R, Mueller T.

Eur J Med Chem. 2019 Feb 1;163:160-168. doi: 10.1016/j.ejmech.2018.11.055. Epub 2018 Nov 23.

PMID:
30503940
12.

New (arene)ruthenium(II) complexes of 4‑aryl‑4H‑naphthopyrans with anticancer and anti-vascular activities.

Schmitt F, Kasparkova J, Brabec V, Begemann G, Schobert R, Biersack B.

J Inorg Biochem. 2018 Jul;184:69-78. doi: 10.1016/j.jinorgbio.2018.03.013. Epub 2018 Apr 5.

PMID:
29684697
13.

Halogenated Bis(methoxybenzylidene)-4-piperidone Curcuminoids with Improved Anticancer Activity.

Schmitt F, Subramaniam D, Anant S, Padhye S, Begemann G, Schobert R, Biersack B.

ChemMedChem. 2018 Jun 6;13(11):1115-1123. doi: 10.1002/cmdc.201800135. Epub 2018 Apr 23.

PMID:
29570947
14.

Recent developments concerning the application of the Mannich reaction for drug design.

Biersack B, Ahmed K, Padhye S, Schobert R.

Expert Opin Drug Discov. 2018 Jan;13(1):39-49. doi: 10.1080/17460441.2018.1403420. Epub 2017 Nov 14. Review.

PMID:
29137490
15.

Animacroxam, a Novel Dual-Mode Compound Targeting Histone Deacetylases and Cytoskeletal Integrity of Testicular Germ Cell Cancer Cells.

Steinemann G, Dittmer A, Kuzyniak W, Hoffmann B, Schrader M, Schobert R, Biersack B, Nitzsche B, Höpfner M.

Mol Cancer Ther. 2017 Nov;16(11):2364-2374. doi: 10.1158/1535-7163.MCT-17-0293. Epub 2017 Aug 24.

16.

Fluoro and pentafluorothio analogs of the antitumoral curcuminoid EF24 with superior antiangiogenic and vascular-disruptive effects.

Schmitt F, Gold M, Begemann G, Andronache I, Biersack B, Schobert R.

Bioorg Med Chem. 2017 Sep 1;25(17):4894-4903. doi: 10.1016/j.bmc.2017.07.039. Epub 2017 Jul 21.

PMID:
28774574
17.

Anti-trypanosomal activity of cationic N-heterocyclic carbene gold(I) complexes.

Winter I, Lockhauserbäumer J, Lallinger-Kube G, Schobert R, Ersfeld K, Biersack B.

Mol Biochem Parasitol. 2017 Jun;214:112-120. doi: 10.1016/j.molbiopara.2017.05.001. Epub 2017 May 15.

PMID:
28522152
18.

Multimodal HDAC Inhibitors with Improved Anticancer Activity.

Schobert R, Biersack B.

Curr Cancer Drug Targets. 2018;18(1):39-56. doi: 10.2174/1568009617666170206102613. Review.

PMID:
28176653
19.

Chemical and Biological Aspects of the Natural 1,4-Benzoquinone Embelin and its (semi-)Synthetic Derivatives.

Shuveksh PS, Ahmed K, Padhye S, Schobert R, Biersack B.

Curr Med Chem. 2017;24(18):1998-2009. doi: 10.2174/0929867324666170116125731. Review.

PMID:
28093981
20.

Improved anticancer and antiparasitic activity of new lawsone Mannich bases.

Mahal K, Ahmad A, Schmitt F, Lockhauserbäumer J, Starz K, Pradhan R, Padhye S, Sarkar FH, Koko WS, Schobert R, Ersfeld K, Biersack B.

Eur J Med Chem. 2017 Jan 27;126:421-431. doi: 10.1016/j.ejmech.2016.11.043. Epub 2016 Nov 22.

PMID:
27912173

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