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Items: 1 to 20 of 99

1.

miR-181a Modulation of ERK-MAPK Signaling Sustains DC-SIGN Expression and Limits Activation of Monocyte-Derived Dendritic Cells.

Lim CX, Lee B, Geiger O, Passegger C, Beitzinger M, Romberger J, Stracke A, Högenauer C, Stift A, Stoiber H, Poidinger M, Zebisch A, Meister G, Williams A, Flavell RA, Henao-Mejia J, Strobl H.

Cell Rep. 2020 Mar 17;30(11):3793-3805.e5. doi: 10.1016/j.celrep.2020.02.077.

2.

TREM-1 activation is a potential key regulator in driving severe pathogenesis of enterovirus A71 infection.

Amrun SN, Tan JJL, Rickett NY, Cox JA, Lee B, Griffiths MJ, Solomon T, Perera D, Ooi MH, Hiscox JA, Ng LFP.

Sci Rep. 2020 Mar 2;10(1):3810. doi: 10.1038/s41598-020-60761-5.

3.

Erratum: Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients.

Amrun SN, Yee WX, Abu Bakar F, Lee B, Kam YW, Lum FM, Tan JJ, Lim VW, Watthanaworawit W, Ling C, Nosten F, Renia L, Leo YS, Ng LF.

Clin Transl Immunology. 2020 Feb 19;9(2):e01118. doi: 10.1002/cti2.1118. eCollection 2020.

4.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Takata K, Kozaki T, Lee CZW, Thion MS, Otsuka M, Lim S, Utami KH, Fidan K, Park DS, Malleret B, Chakarov S, See P, Low D, Low G, Garcia-Miralles M, Zeng R, Zhang J, Goh CC, Gul A, Hubert S, Lee B, Chen J, Low I, Shadan NB, Lum J, Wei TS, Mok E, Kawanishi S, Kitamura Y, Larbi A, Poidinger M, Renia L, Ng LG, Wolf Y, Jung S, Önder T, Newell E, Huber T, Ashihara E, Garel S, Pouladi MA, Ginhoux F.

Immunity. 2020 Feb 18;52(2):417-418. doi: 10.1016/j.immuni.2020.01.004. No abstract available.

PMID:
32075730
5.

Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway.

Kared H, Tan SW, Lau MC, Chevrier M, Tan C, How W, Wong G, Strickland M, Malleret B, Amoah A, Pilipow K, Zanon V, Govern NM, Lum J, Chen JM, Lee B, Florian MC, Geiger H, Ginhoux F, Ruiz-Mateos E, Fulop T, Rajasuriar R, Kamarulzaman A, Ng TP, Lugli E, Larbi A.

Nat Commun. 2020 Feb 10;11(1):821. doi: 10.1038/s41467-020-14442-6.

6.

Multiplex immunohistochemistry/immunofluorescence (mIHC/IF) for PD-L1 testing in triple-negative breast cancer: a translational assay compared with conventional IHC.

Yeong J, Tan T, Chow ZL, Cheng Q, Lee B, Seet A, Lim JX, Lim JCT, Ong CCH, Thike AA, Saraf S, Tan BYC, Poh YC, Yee S, Liu J, Lim E, Iqbal J, Dent R, Tan PH.

J Clin Pathol. 2020 Jan 22. pii: jclinpath-2019-206252. doi: 10.1136/jclinpath-2019-206252. [Epub ahead of print]

PMID:
31969377
7.

Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates.

Chng MHY, Lim MQ, Rouers A, Becht E, Lee B, MacAry PA, Lye DC, Leo YS, Chen J, Fink K, Rivino L, Newell EW.

Immunity. 2019 Dec 17;51(6):1119-1135.e5. doi: 10.1016/j.immuni.2019.10.007. Epub 2019 Nov 19.

PMID:
31757672
8.

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation.

Kumar D, Lee B, Puan KJ, Lee W, Luis BS, Yusof N, Andiappan AK, Del Rosario R, Poschmann J, Kumar P, DeLibero G, Singhal A, Prabhakar S, De Yun W, Poidinger M, Rötzschke O.

Sci Rep. 2019 Oct 23;9(1):15245. doi: 10.1038/s41598-019-51592-0.

9.

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

Dutertre CA, Becht E, Irac SE, Khalilnezhad A, Narang V, Khalilnezhad S, Ng PY, van den Hoogen LL, Leong JY, Lee B, Chevrier M, Zhang XM, Yong PJA, Koh G, Lum J, Howland SW, Mok E, Chen J, Larbi A, Tan HKK, Lim TKH, Karagianni P, Tzioufas AG, Malleret B, Brody J, Albani S, van Roon J, Radstake T, Newell EW, Ginhoux F.

Immunity. 2019 Sep 17;51(3):573-589.e8. doi: 10.1016/j.immuni.2019.08.008. Epub 2019 Aug 29.

PMID:
31474513
10.

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.

Tan KS, Andiappan AK, Lee B, Yan Y, Liu J, Tang SA, Lum J, He TT, Ong YK, Thong M, Lim HF, Choi HW, Rotzschke O, Chow VT, Wang Y.

Cells. 2019 Aug 27;8(9). pii: E986. doi: 10.3390/cells8090986.

11.

Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps.

Peng Y, Zi XX, Tian TF, Lee B, Lum J, Tang SA, Tan KS, Qiu QH, Ye J, Shi L, Guan WJ, Andiappan AK, Wang Y.

Eur Respir J. 2019 Nov 14;54(5). pii: 1900732. doi: 10.1183/13993003.00732-2019. Print 2019 Nov.

PMID:
31439685
12.

Evaluation of phospho-histone H3 in Asian triple-negative breast cancer using multiplex immunofluorescence.

Lai CPT, Yeong JPS, Tan AS, Ong CHC, Lee B, Lim JCT, Thike AA, Iqbal J, Dent RA, Lim EH, Tan PH.

Breast Cancer Res Treat. 2019 Nov;178(2):295-305. doi: 10.1007/s10549-019-05396-5. Epub 2019 Aug 13.

PMID:
31410680
13.

The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach.

Tan AS, Yeong JPS, Lai CPT, Ong CHC, Lee B, Lim JCT, Thike AA, Iqbal J, Dent RA, Lim EH, Tan PH.

Virchows Arch. 2019 Dec;475(6):709-725. doi: 10.1007/s00428-019-02635-4. Epub 2019 Aug 12.

PMID:
31407032
14.

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis.

Javanmard Khameneh H, Leong KWK, Mencarelli A, Vacca M, Mambwe B, Neo K, Tay A, Zolezzi F, Lee B, Mortellaro A.

Front Immunol. 2019 Jul 15;10:1566. doi: 10.3389/fimmu.2019.01566. eCollection 2019.

15.

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients.

Amrun SN, Yee WX, Abu Bakar F, Lee B, Kam YW, Lum FM, Tan JJ, Lim VW, Watthanaworawit W, Ling C, Nosten F, Renia L, Leo YS, Ng LF.

Clin Transl Immunology. 2019 Jul 26;8(7):e1066. doi: 10.1002/cti2.1066. eCollection 2019. Erratum in: Clin Transl Immunology. 2020 Feb 19;9(2):e01118.

16.

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.

Porcu E, Rüeger S, Lepik K; eQTLGen Consortium; BIOS Consortium, Santoni FA, Reymond A, Kutalik Z.

Nat Commun. 2019 Jul 24;10(1):3300. doi: 10.1038/s41467-019-10936-0.

17.

Oxygen-Mediated Control of the Keratinocyte Proliferation-Differentiation Axis.

Koh R, Szeverényi I, Lee B, Denil SLIJ, Lim SYJ, Benny PA, Grasset N, Tan BK, Lane EB.

J Invest Dermatol. 2020 Jan;140(1):235-238.e3. doi: 10.1016/j.jid.2019.05.030. Epub 2019 Jul 5. No abstract available.

PMID:
31283927
18.

Detection and characterization of a novel marine birnavirus isolated from Asian seabass in Singapore.

Chen J, Toh X, Ong J, Wang Y, Teo XH, Lee B, Wong PS, Khor D, Chong SM, Chee D, Wee A, Wang Y, Ng MK, Tan BH, Huangfu T.

Virol J. 2019 May 28;16(1):71. doi: 10.1186/s12985-019-1174-0.

19.

RIG-I Activation by a Designer Short RNA Ligand Protects Human Immune Cells against Dengue Virus Infection without Causing Cytotoxicity.

Ho V, Yong HY, Chevrier M, Narang V, Lum J, Toh YX, Lee B, Chen J, Tan EY, Luo D, Fink K.

J Virol. 2019 Jun 28;93(14). pii: e00102-19. doi: 10.1128/JVI.00102-19. Print 2019 Jul 15.

20.

Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate.

Chan YH, Teo TH, Utt A, Tan JJ, Amrun SN, Abu Bakar F, Yee WX, Becht E, Lee CY, Lee B, Rajarethinam R, Newell E, Merits A, Carissimo G, Lum FM, Ng LF.

EMBO Mol Med. 2019 Jun;11(6). pii: e10092. doi: 10.15252/emmm.201810092.

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