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Risk of de novo Hepatocellular Carcinoma after HCV Treatment with Direct-Acting Antivirals.

Finkelmeier F, Dultz G, Peiffer KH, Kronenberger B, Krauss F, Zeuzem S, Sarrazin C, Vermehren J, Waidmann O.

Liver Cancer. 2018 May;7(2):190-204. doi: 10.1159/000486812. Epub 2018 Mar 1.


Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition.

Ibrahim AA, Schmithals C, Kowarz E, Köberle V, Kakoschky B, Pleli T, Kollmar O, Nitsch S, Waidmann O, Finkelmeier F, Zeuzem S, Korf HW, Schmid T, Weigert A, Kronenberger B, Marschalek R, Piiper A.

Clin Cancer Res. 2017 Jul 15;23(14):3896-3905. doi: 10.1158/1078-0432.CCR-16-1762. Epub 2017 Feb 6.


High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis.

Finkelmeier F, Canli Ö, Tal A, Pleli T, Trojan J, Schmidt M, Kronenberger B, Zeuzem S, Piiper A, Greten FR, Waidmann O.

Eur J Cancer. 2016 May;59:152-159. doi: 10.1016/j.ejca.2016.03.002. Epub 2016 Mar 31.


Cytokeratin 18-based cell death markers indicate severity of liver disease and prognosis of cirrhotic patients.

Waidmann O, Brunner F, Herrmann E, Zeuzem S, Piiper A, Kronenberger B.

Liver Int. 2016 Oct;36(10):1464-72. doi: 10.1111/liv.13117. Epub 2016 Apr 4.


Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma.

Grammatikos G, Schoell N, Ferreirós N, Bon D, Herrmann E, Farnik H, Köberle V, Piiper A, Zeuzem S, Kronenberger B, Waidmann O, Pfeilschifter J.

Oncotarget. 2016 Apr 5;7(14):18095-105. doi: 10.18632/oncotarget.7741.


Vesicle-associated microRNAs are released from blood cells on incubation of blood samples.

Köberle V, Kakoschky B, Ibrahim AA, Schmithals C, Peveling-Oberhag J, Zeuzem S, Kronenberger B, Waidmann O, Pleli T, Piiper A.

Transl Res. 2016 Mar;169:40-6. doi: 10.1016/j.trsl.2015.10.010. Epub 2015 Nov 5.


Combined percutaneous retrograde and peroral antegrade esophagoscopy for the treatment of complete upper esophageal obstruction.

Lange CM, Kronenberger B, Hausmann J, Zeuzem S, Albert J.

Endoscopy. 2015;47 Suppl 1 UCTN:E531. doi: 10.1055/s-0034-1393041. Epub 2015 Nov 3. No abstract available.


Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis.

Grammatikos G, Ferreiròs N, Waidmann O, Bon D, Schroeter S, Koch A, Herrmann E, Zeuzem S, Kronenberger B, Pfeilschifter J.

PLoS One. 2015 Sep 18;10(9):e0138130. doi: 10.1371/journal.pone.0138130. eCollection 2015.


Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma.

Schmithals C, Köberle V, Korkusuz H, Pleli T, Kakoschky B, Augusto EA, Ibrahim AA, Arencibia JM, Vafaizadeh V, Groner B, Korf HW, Kronenberger B, Zeuzem S, Vogl TJ, Waidmann O, Piiper A.

Cancer Res. 2015 Aug 1;75(15):3147-54. doi: 10.1158/0008-5472.CAN-15-0395.


Low 25-Hydroxyvitamin D Levels Are Associated with Infections and Mortality in Patients with Cirrhosis.

Finkelmeier F, Kronenberger B, Zeuzem S, Piiper A, Waidmann O.

PLoS One. 2015 Jun 29;10(6):e0132119. doi: 10.1371/journal.pone.0132119. eCollection 2015.


No Distal Migration in Unfixed Versus Fixed Cell Structure Covered Self-Expanding Metal Stents for Treatment of Benign Biliary Disease.

Walter D, Sarrazin C, Trojan J, Kronenberger B, Bojunga J, Zeuzem S, Friedrich-Rust M, Albert JG.

Dig Dis Sci. 2015 Aug;60(8):2495-501. doi: 10.1007/s10620-015-3656-2. Epub 2015 Apr 14.


Colonisation with multidrug-resistant bacteria is associated with increased mortality in patients with cirrhosis.

Waidmann O, Kempf VA, Brandt C, Zeuzem S, Piiper A, Kronenberger B.

Gut. 2015 Jul;64(7):1183-4. doi: 10.1136/gutjnl-2014-309104. Epub 2015 Jan 23. No abstract available.


A novel, stiff-shaft, flexible-tip guidewire for cannulation of biliary stricture during endoscopic retrograde cholangiopancreatography: a randomized trial.

Albert JG, Lucas K, Filmann N, Herrmann E, Schröder O, Sarrazin C, Trojan J, Kronenberger B, Bojunga J, Zeuzem S, Friedrich-Rust M.

Endoscopy. 2014 Oct;46(10):857-61. doi: 10.1055/s-0034-1377628. Epub 2014 Sep 10. Erratum in: Endoscopy. 2014 Oct;46(10):c1.


Serum autotaxin is a parameter for the severity of liver cirrhosis and overall survival in patients with liver cirrhosis--a prospective cohort study.

Pleli T, Martin D, Kronenberger B, Brunner F, Köberle V, Grammatikos G, Farnik H, Martinez Y, Finkelmeier F, Labocha S, Ferreirós N, Zeuzem S, Piiper A, Waidmann O.

PLoS One. 2014 Jul 25;9(7):e103532. doi: 10.1371/journal.pone.0103532. eCollection 2014.


Telaprevir drug monitoring during antiviral therapy of hepatitis C graft infection after liver transplantation.

Farnik H, Zimmermann T, Herrmann E, Bechstein WO, Kronenberger B, Galle PR, Labocha S, Ferreiros N, Geisslinger G, Zeuzem S, Sarrazin C, Welker MW.

Liver Int. 2015 Jan;35(1):176-83. doi: 10.1111/liv.12532. Epub 2014 Apr 9.


Single measurement of hemoglobin predicts outcome of HCC patients.

Finkelmeier F, Bettinger D, Köberle V, Schultheiß M, Zeuzem S, Kronenberger B, Piiper A, Waidmann O.

Med Oncol. 2014 Jan;31(1):806. doi: 10.1007/s12032-013-0806-2. Epub 2013 Dec 11.


Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers.

Köberle V, Pleli T, Schmithals C, Augusto Alonso E, Haupenthal J, Bönig H, Peveling-Oberhag J, Biondi RM, Zeuzem S, Kronenberger B, Waidmann O, Piiper A.

PLoS One. 2013 Sep 20;8(9):e75184. doi: 10.1371/journal.pone.0075184. eCollection 2013.


Baseline MELD score predicts hepatic decompensation during antiviral therapy in patients with chronic hepatitis C and advanced cirrhosis.

Dultz G, Seelhof M, Herrmann E, Welker MW, Friedrich-Rust M, Teuber G, Kronenberger B, von Wagner M, Vermehren J, Sarrazin C, Zeuzem S, Hofmann WP.

PLoS One. 2013 Aug 1;8(8):e71262. doi: 10.1371/journal.pone.0071262. Print 2013.


Investigation of viral escape mutations within HCV p7 during treatment with amantadine in patients with chronic hepatitis C.

Vermehren A, Welsch C, Elsler U, Vermehren J, Herrmann E, Sarrazin C, von Wagner M, Susser S, Hofmann WP, Kronenberger B, Zeuzem S, Mihm U.

Antivir Ther. 2013;18(6):803-11. doi: 10.3851/IMP2663. Epub 2013 Jul 3.


Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma.

Köberle V, Kronenberger B, Pleli T, Trojan J, Imelmann E, Peveling-Oberhag J, Welker MW, Elhendawy M, Zeuzem S, Piiper A, Waidmann O.

Eur J Cancer. 2013 Nov;49(16):3442-9. doi: 10.1016/j.ejca.2013.06.002. Epub 2013 Jun 26.


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