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Items: 19


Unaltered intravenous prion disease pathogenesis in the temporary absence of marginal zone B cells.

Bradford BM, Mabbott NA.

Sci Rep. 2019 Dec 13;9(1):19119. doi: 10.1038/s41598-019-55772-w.


Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression.

Bradford BM, Wijaya CAW, Mabbott NA.

Front Cell Neurosci. 2019 Sep 10;13:411. doi: 10.3389/fncel.2019.00411. eCollection 2019.


Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice.

Sánchez-Quintero A, Bradford BM, Maizels R, Donaldson DS, Mabbott NA.

Sci Rep. 2019 Apr 30;9(1):6674. doi: 10.1038/s41598-019-42900-9.


Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.

Melo-Gonzalez F, Kammoun H, Evren E, Dutton EE, Papadopoulou M, Bradford BM, Tanes C, Fardus-Reid F, Swann JR, Bittinger K, Mabbott NA, Vallance BA, Willinger T, Withers DR, Hepworth MR.

J Exp Med. 2019 Apr 1;216(4):728-742. doi: 10.1084/jem.20180871. Epub 2019 Feb 27.


Type I interferon induces CXCL13 to support ectopic germinal center formation.

Denton AE, Innocentin S, Carr EJ, Bradford BM, Lafouresse F, Mabbott NA, Mörbe U, Ludewig B, Groom JR, Good-Jacobson KL, Linterman MA.

J Exp Med. 2019 Mar 4;216(3):621-637. doi: 10.1084/jem.20181216. Epub 2019 Feb 5.


Oral Prion Neuroinvasion Occurs Independently of PrPC Expression in the Gut Epithelium.

Marshall A, Bradford BM, Clarke AR, Manson JC, Mabbott NA.

J Virol. 2018 Sep 12;92(19). pii: e01010-18. doi: 10.1128/JVI.01010-18. Print 2018 Oct 1.


Increased susceptibility to oral Trichuris muris infection in the specific absence of CXCR5+ CD11c+ cells.

Bradford BM, Donaldson DS, Forman R, Else KJ, Mabbott NA.

Parasite Immunol. 2018 Aug;40(8):e12566. doi: 10.1111/pim.12566.


Prion disease pathogenesis in the absence of the commensal microbiota.

Bradford BM, Tetlow L, Mabbott NA.

J Gen Virol. 2017 Jul;98(7):1943-1952. doi: 10.1099/jgv.0.000860. Epub 2017 Jul 15.


Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells.

Bradford BM, Reizis B, Mabbott NA.

J Virol. 2017 Apr 28;91(10). pii: e00124-17. doi: 10.1128/JVI.00124-17. Print 2017 May 15.


Prion pathogenesis is unaltered following down-regulation of SIGN-R1.

Bradford BM, Brown KL, Mabbott NA.

Virology. 2016 Oct;497:337-345. doi: 10.1016/j.virol.2016.08.005. Epub 2016 Aug 11.


Human prion diseases and the risk of their transmission during anatomical dissection.

Bradford BM, Piccardo P, Ironside JW, Mabbott NA.

Clin Anat. 2014 Sep;27(6):821-32. doi: 10.1002/ca.22403. Epub 2014 Apr 17. Review.


Aging and the mucosal immune system in the intestine.

Mabbott NA, Kobayashi A, Sehgal A, Bradford BM, Pattison M, Donaldson DS.

Biogerontology. 2015 Apr;16(2):133-45. doi: 10.1007/s10522-014-9498-z. Epub 2014 Apr 5. Review.


Peripheral prion disease pathogenesis is unaltered in the absence of sialoadhesin (Siglec-1/CD169).

Bradford BM, Crocker PR, Mabbott NA.

Immunology. 2014 Sep;143(1):120-9. doi: 10.1111/imm.12294.


Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.

Sauter KA, Pridans C, Sehgal A, Tsai YT, Bradford BM, Raza S, Moffat L, Gow DJ, Beard PM, Mabbott NA, Smith LB, Hume DA.

J Leukoc Biol. 2014 Aug;96(2):265-74. doi: 10.1189/jlb.2A0114-006R. Epub 2014 Mar 20.


Prion disease and the innate immune system.

Bradford BM, Mabbott NA.

Viruses. 2012 Dec;4(12):3389-419. Review.


Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen.

McCulloch L, Brown KL, Bradford BM, Hopkins J, Bailey M, Rajewsky K, Manson JC, Mabbott NA.

PLoS Pathog. 2011 Dec;7(12):e1002402. doi: 10.1371/journal.ppat.1002402. Epub 2011 Dec 1.


Glycosylation of PrPC determines timing of neuroinvasion and targeting in the brain following transmissible spongiform encephalopathy infection by a peripheral route.

Cancellotti E, Bradford BM, Tuzi NL, Hickey RD, Brown D, Brown KL, Barron RM, Kisielewski D, Piccardo P, Manson JC.

J Virol. 2010 Apr;84(7):3464-75. doi: 10.1128/JVI.02374-09. Epub 2010 Jan 27.


Dramatic reduction of PrP C level and glycosylation in peripheral nerves following PrP knock-out from Schwann cells does not prevent transmissible spongiform encephalopathy neuroinvasion.

Bradford BM, Tuzi NL, Feltri ML, McCorquodale C, Cancellotti E, Manson JC.

J Neurosci. 2009 Dec 9;29(49):15445-54. doi: 10.1523/JNEUROSCI.4195-09.2009.

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