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Items: 1 to 20 of 69


A novel and efficient subcritical butane extraction method and UHPLC analysis of oxyprenylated phenylpropanoids from grapefruits peels.

Genovese S, Epifano F, Preziuso F, Stefanucci A, Scotti L, Bucciarelli T, di Profio P, Canale V, Fiorito S.

J Pharm Biomed Anal. 2020 Feb 24;184:113185. doi: 10.1016/j.jpba.2020.113185. [Epub ahead of print]


Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists.

Szűcs E, Stefanucci A, Dimmito MP, Zádor F, Pieretti S, Zengin G, Vécsei L, Benyhe S, Nalli M, Mollica A.

Biomolecules. 2020 Feb 12;10(2). pii: E284. doi: 10.3390/biom10020284.


Phenolic Profile, Toxicity, Enzyme Inhibition, In Silico Studies, and Antioxidant Properties of Cakile maritima Scop. (Brassicaceae) from Southern Portugal.

Placines C, Castañeda-Loaiza V, João Rodrigues M, Pereira CG, Stefanucci A, Mollica A, Zengin G, Llorent-Martínez EJ, Castilho PC, Custódio AL.

Plants (Basel). 2020 Jan 22;9(2). pii: E142. doi: 10.3390/plants9020142.


Effects of genistein on blood pressure: A systematic review and meta-analysis.

Hemati N, Asis M, Moradi S, Mollica A, Stefanucci A, Nikfar S, Mohammadi E, Farzaei MH, Abdollahi M.

Food Res Int. 2020 Feb;128:108764. doi: 10.1016/j.foodres.2019.108764. Epub 2019 Oct 31.


Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.

Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht KL, Streicher JM, Mollica A.

J Med Chem. 2020 Mar 12;63(5):2673-2687. doi: 10.1021/acs.jmedchem.9b01963. Epub 2019 Dec 27.


Chemical profile, antiproliferative, antioxidant, and enzyme inhibition activities and docking studies of Cymbopogon schoenanthus (L.) Spreng. and Cymbopogon nervatus (Hochst.) Chiov. from Sudan.

Yagi S, Mohammed ABA, Tzanova T, Schohn H, Abdelgadir H, Stefanucci A, Mollica A, Zengin G.

J Food Biochem. 2020 Feb;44(2):e13107. doi: 10.1111/jfbc.13107. Epub 2019 Dec 6.


Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening.

Poli G, Dimmito MP, Mollica A, Zengin G, Benyhe S, Zador F, Stefanucci A.

Molecules. 2019 Oct 27;24(21). pii: E3872. doi: 10.3390/molecules24213872.


Designing new generation of potent inhibitors against membrane-type matrix metalloproteinase-2: a computational effort against multiple myeloma.

Fakhari S, Stefanucci A, Mollica A, Nikkhoo B, Tafsiri E, Jalili A, Mirzaie S.

J Biomol Struct Dyn. 2019 Oct 16:1-13. doi: 10.1080/07391102.2019.1670736. [Epub ahead of print]


Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.

Dimmito MP, Stefanucci A, Pieretti S, Minosi P, Dvorácskó S, Tömböly C, Zengin G, Mollica A.

Biomolecules. 2019 Sep 16;9(9). pii: E492. doi: 10.3390/biom9090492.


Multi-targeted potential of Pittosporum senacia Putt.: HPLC-ESI-MSn analysis, in silico docking, DNA protection, antimicrobial, enzyme inhibition, anti-cancer and apoptotic activity.

Mahomoodally MF, Picot-Allain C, Hosenally M, Ugurlu A, Mollica A, Stefanucci A, Llorent-Martínez EJ, Baloglu MC, Zengin G.

Comput Biol Chem. 2019 Dec;83:107114. doi: 10.1016/j.compbiolchem.2019.107114. Epub 2019 Aug 29.


Nanoformulations of natural products for management of metabolic syndrome.

Taghipour YD, Hajialyani M, Naseri R, Hesari M, Mohammadi P, Stefanucci A, Mollica A, Farzaei MH, Abdollahi M.

Int J Nanomedicine. 2019 Jul 16;14:5303-5321. doi: 10.2147/IJN.S213831. eCollection 2019. Review.


Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors.

Dvorácskó S, Keresztes A, Mollica A, Stefanucci A, Macedonio G, Pieretti S, Zádor F, Walter FR, Deli MA, Kékesi G, Bánki L, Tuboly G, Horváth G, Tömböly C.

Eur J Med Chem. 2019 Sep 15;178:571-588. doi: 10.1016/j.ejmech.2019.05.037. Epub 2019 May 21.


Chemical profiling, antioxidant, enzyme inhibitory and molecular modelling studies on the leaves and stem bark extracts of three African medicinal plants.

Bibi Sadeer N, Llorent-Martínez EJ, Bene K, Fawzi Mahomoodally M, Mollica A, Ibrahime Sinan K, Stefanucci A, Ruiz-Riaguas A, Fernández-de Córdova ML, Zengin G.

J Pharm Biomed Anal. 2019 Sep 10;174:19-33. doi: 10.1016/j.jpba.2019.05.041. Epub 2019 May 22.


Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: in Vivo and in Vitro Biological Profile.

Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A.

ACS Med Chem Lett. 2019 Mar 8;10(4):450-456. doi: 10.1021/acsmedchemlett.8b00495. eCollection 2019 Apr 11.


On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity.

Stefanucci A, Lei W, Pieretti S, Novellino E, Dimmito MP, Marzoli F, Streicher JM, Mollica A.

Sci Rep. 2019 Apr 8;9(1):5771. doi: 10.1038/s41598-019-42289-5.


Anti-Oxidant and Tyrosinase Inhibitory In Vitro Activity of Amino Acids and Small Peptides: New Hints for the Multifaceted Treatment of Neurologic and Metabolic Disfunctions.

Luisi G, Stefanucci A, Zengin G, Dimmito MP, Mollica A.

Antioxidants (Basel). 2018 Dec 26;8(1). pii: E7. doi: 10.3390/antiox8010007.


Exploring the halophyte Cistanche phelypaea (L.) Cout as a source of health promoting products: In vitro antioxidant and enzyme inhibitory properties, metabolomic profile and computational studies.

Trampetti F, Pereira C, Rodrigues MJ, Celaj O, D'Abrosca B, Zengin G, Mollica A, Stefanucci A, Custódio L.

J Pharm Biomed Anal. 2019 Feb 20;165:119-128. doi: 10.1016/j.jpba.2018.11.053. Epub 2018 Nov 24.


Discovery of arginine-containing tripeptides as a new class of pancreatic lipase inhibitors.

Stefanucci A, Luisi G, Zengin G, Macedonio G, Dimmito MP, Novellino E, Mollica A.

Future Med Chem. 2019 Jan;11(1):5-19. doi: 10.4155/fmc-2018-0216. Epub 2018 Dec 11.


Biochemical and pharmacological investigation of novel nociceptin/OFQ analogues and N/OFQ-RYYRIK hybrid peptides.

Erdei AI, Borbély A, Magyar A, Szűcs E, Ötvös F, Gombos D, Al-Khrasani M, Stefanucci A, Dimmito MP, Luisi G, Mollica A, Benyhe S.

Peptides. 2019 Feb;112:106-113. doi: 10.1016/j.peptides.2018.11.010. Epub 2018 Dec 1.


Multifunctional approaches to provide potential pharmacophores for the pharmacy shelf: Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt.

Uysal A, Ozer OY, Zengin G, Stefanucci A, Mollica A, Picot-Allain CMN, Mahomoodally MF.

Comput Biol Chem. 2019 Feb;78:64-73. doi: 10.1016/j.compbiolchem.2018.11.018. Epub 2018 Nov 20.


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