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Items: 11

1.

New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action.

Ohui K, Afanasenko E, Bacher F, Ting RLX, Zafar A, Blanco-Cabra N, Torrents E, Dömötör O, May NV, Darvasiova D, Enyedy ÉA, Popović-Bijelić A, Reynisson J, Rapta P, Babak MV, Pastorin G, Arion VB.

J Med Chem. 2019 Jan 24;62(2):512-530. doi: 10.1021/acs.jmedchem.8b01031. Epub 2018 Dec 18.

2.

From Catalysis to Cancer: Toward Structure-Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents.

Lam NYS, Truong D, Burmeister H, Babak MV, Holtkamp HU, Movassaghi S, Ayine-Tora DM, Zafar A, Kubanik M, Oehninger L, Söhnel T, Reynisson J, Jamieson SMF, Gaiddon C, Ott I, Hartinger CG.

Inorg Chem. 2018 Nov 19;57(22):14427-14434. doi: 10.1021/acs.inorgchem.8b02634. Epub 2018 Nov 8.

PMID:
30406647
3.

A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold.

Li-Zhulanov NS, Zakharenko AL, Chepanova AA, Patel J, Zafar A, Volcho KP, Salakhutdinov NF, Reynisson J, Leung IKH, Lavrik OI.

Molecules. 2018 Sep 26;23(10). pii: E2468. doi: 10.3390/molecules23102468.

4.

Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors.

Zakharova O, Luzina O, Zakharenko A, Sokolov D, Filimonov A, Dyrkheeva N, Chepanova A, Ilina E, Ilyina A, Klabenkova K, Chelobanov B, Stetsenko D, Zafar A, Eurtivong C, Reynisson J, Volcho K, Salakhutdinov N, Lavrik O.

Bioorg Med Chem. 2018 Aug 15;26(15):4470-4480. doi: 10.1016/j.bmc.2018.07.039. Epub 2018 Jul 24.

PMID:
30076000
5.

Prevalence and Treatment of Untypable HCV Variants in Different Districts of Punjab, Pakistan.

Zafar A, Imran M, Zahoor S, Shah ZH, Ali M, Afzal MS.

Viral Immunol. 2018 Jul/Aug;31(6):426-432. doi: 10.1089/vim.2017.0167. Epub 2018 Jun 19.

PMID:
29920175
6.
7.

Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Zafar A, Pilkington LI, Haverkate NA, van Rensburg M, Leung E, Kumara S, Denny WA, Barker D, Alsuraifi A, Hoskins C, Reynisson J.

Molecules. 2018 Jan 11;23(1). pii: E145. doi: 10.3390/molecules23010145.

8.

GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Zafar A, Sari S, Leung E, Pilkington LI, van Rensburg M, Barker D, Reynisson J.

Molecules. 2017 Dec 18;22(12). pii: E2254. doi: 10.3390/molecules22122254.

9.

Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors.

Ponomarev KY, Suslov EV, Zakharenko AL, Zakharova OD, Rogachev AD, Korchagina DV, Zafar A, Reynisson J, Nefedov AA, Volcho KP, Salakhutdinov NF, Lavrik OI.

Bioorg Chem. 2018 Feb;76:392-399. doi: 10.1016/j.bioorg.2017.12.005. Epub 2017 Dec 9.

PMID:
29248742
10.

Hydration Free Energy as a Molecular Descriptor in Drug Design: A Feasibility Study.

Zafar A, Reynisson J.

Mol Inform. 2016 May;35(5):207-14. doi: 10.1002/minf.201501035. Epub 2016 Apr 13.

PMID:
27492087
11.

Breast cancer screening practices and awareness in women admitted to a tertiary care hospital of Lahore, Pakistan.

Maqsood B, Zeeshan MM, Rehman F, Aslam F, Zafar A, Syed B, Qadeer K, Ajmal S, Imam SZ.

J Pak Med Assoc. 2009 Jun;59(6):418-21.

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