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Items: 1 to 20 of 42


The Sialic Acid-Dependent Nematocyst Discharge Process in Relation to Its Physical-Chemical Properties Is A Role Model for Nanomedical Diagnostic and Therapeutic Tools.

Zhang R, Jin L, Zhang N, Petridis AK, Eckert T, Scheiner-Bobis G, Bergmann M, Scheidig A, Schauer R, Yan M, Wijesundera SA, Nordén B, Chatterjee BK, Siebert HC.

Mar Drugs. 2019 Aug 12;17(8). pii: E469. doi: 10.3390/md17080469.


KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.

Bartels AK, Göttert S, Desel C, Schäfer M, Krossa S, Scheidig AJ, Grötzinger J, Lorenzen I.

Cell Physiol Biochem. 2019;52(4):850-868. doi: 10.33594/000000059.


Nanomedical Relevance of the Intermolecular Interaction Dynamics-Examples from Lysozymes and Insulins.

Zhang R, Zhang N, Mohri M, Wu L, Eckert T, Krylov VB, Antosova A, Ponikova S, Bednarikova Z, Markart P, Günther A, Norden B, Billeter M, Schauer R, Scheidig AJ, Ratha BN, Bhunia A, Hesse K, Enani MA, Steinmeyer J, Petridis AK, Kozar T, Gazova Z, Nifantiev NE, Siebert HC.

ACS Omega. 2019 Feb 28;4(2):4206-4220. doi: 10.1021/acsomega.8b02471. Epub 2019 Feb 27.


Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes.

Kubitza C, Bittner F, Ginsel C, Havemeyer A, Clement B, Scheidig AJ.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11958-11963. doi: 10.1073/pnas.1808576115. Epub 2018 Nov 5.


The Involvement of the Mitochondrial Amidoxime Reducing Component (mARC) in the Reductive Metabolism of Hydroxamic Acids.

Ginsel C, Plitzko B, Froriep D, Stolfa DA, Jung M, Kubitza C, Scheidig AJ, Havemeyer A, Clement B.

Drug Metab Dispos. 2018 Oct;46(10):1396-1402. doi: 10.1124/dmd.118.082453. Epub 2018 Jul 25.


T4 lysozyme-facilitated crystallization of the human molybdenum cofactor-dependent enzyme mARC.

Kubitza C, Ginsel C, Bittner F, Havemeyer A, Clement B, Scheidig AJ.

Acta Crystallogr F Struct Biol Commun. 2018 Jun 1;74(Pt 6):337-344. doi: 10.1107/S2053230X18006921. Epub 2018 May 17.


Crystal structure of pyrrolizidine alkaloid N-oxygenase from the grasshopper Zonocerus variegatus.

Kubitza C, Faust A, Gutt M, Gäth L, Ober D, Scheidig AJ.

Acta Crystallogr D Struct Biol. 2018 May 1;74(Pt 5):422-432. doi: 10.1107/S2059798318003510. Epub 2018 Apr 24.


Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17.

Krossa S, Scheidig AJ, Grötzinger J, Lorenzen I.

Sci Rep. 2018 Jan 18;8(1):1103. doi: 10.1038/s41598-018-19429-4.


Lysozyme's lectin-like characteristics facilitates its immune defense function.

Zhang R, Wu L, Eckert T, Burg-Roderfeld M, Rojas-Macias MA, Lütteke T, Krylov VB, Argunov DA, Datta A, Markart P, Guenther A, Norden B, Schauer R, Bhunia A, Enani MA, Billeter M, Scheidig AJ, Nifantiev NE, Siebert HC.

Q Rev Biophys. 2017 Jan;50:e9. doi: 10.1017/S0033583517000075.


Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.

Kisiela M, Faust A, Ebert B, Maser E, Scheidig AJ.

FEBS J. 2018 Jan;285(2):275-293. doi: 10.1111/febs.14337. Epub 2017 Nov 28.


GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivation.

Schäfer M, Granato DC, Krossa S, Bartels AK, Yokoo S, Düsterhöft S, Koudelka T, Scheidig AJ, Tholey A, Paes Leme AF, Grötzinger J, Lorenzen I.

FEBS Lett. 2017 Nov;591(21):3567-3587. doi: 10.1002/1873-3468.12858. Epub 2017 Oct 11.


Molecular Basis of the Receptor Interactions of Polysialic Acid (polySia), polySia Mimetics, and Sulfated Polysaccharides.

Zhang R, Loers G, Schachner M, Boelens R, Wienk H, Siebert S, Eckert T, Kraan S, Rojas-Macias MA, Lütteke T, Galuska SP, Scheidig A, Petridis AK, Liang S, Billeter M, Schauer R, Steinmeyer J, Schröder JM, Siebert HC.

ChemMedChem. 2016 May 6;11(9):990-1002. doi: 10.1002/cmdc.201500609. Epub 2016 May 2.


Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.

Weiße RH, Faust A, Schmidt M, Schönheit P, Scheidig AJ.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E519-28. doi: 10.1073/pnas.1518614113. Epub 2016 Jan 19.


Structure-Function Relationships of Antimicrobial Peptides and Proteins with Respect to Contact Molecules on Pathogen Surfaces.

Zhang R, Eckert T, Lutteke T, Hanstein S, Scheidig A, Bonvin AM, Nifantiev NE, Kozar T, Schauer R, Enani MA, Siebert HC.

Curr Top Med Chem. 2016;16(1):89-98. Review.


Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1.

Krossa S, Schmitt AD, Hattermann K, Fritsch J, Scheidig AJ, Mehdorn HM, Held-Feindt J.

Oncotarget. 2015 Aug 28;6(25):21029-45.


Impact of chemokines on the properties of spinal cord-derived neural progenitor cells in a rat spinal cord lesion model.

Knerlich-Lukoschus F, Krossa S, Krause J, Mehdorn HM, Scheidig A, Held-Feindt J.

J Neurosci Res. 2015 Apr;93(4):562-71. doi: 10.1002/jnr.23527. Epub 2014 Dec 9.


Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.

Altmeyer M, Amtmann E, Heyl C, Marschner A, Scheidig AJ, Klein CD.

Bioorg Med Chem Lett. 2014 Nov 15;24(22):5310-4. doi: 10.1016/j.bmcl.2014.09.047. Epub 2014 Sep 23.


The structure of substrate-free 1,5-anhydro-D-fructose reductase from Sinorhizobium meliloti 1021 reveals an open enzyme conformation.

Schu M, Faust A, Stosik B, Kohring GW, Giffhorn F, Scheidig AJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):844-9. doi: 10.1107/S1744309113019490. Epub 2013 Jul 27.


EcoTILLING in Beta vulgaris reveals polymorphisms in the FLC-like gene BvFL1 that are associated with annuality and winter hardiness.

Frerichmann SL, Kirchhoff M, Müller AE, Scheidig AJ, Jung C, Kopisch-Obuch FJ.

BMC Plant Biol. 2013 Mar 25;13:52. doi: 10.1186/1471-2229-13-52.

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