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Vibrational spectral analysis, XRD-structure, computation, exo⇔endo isomerization and non-linear optical crystal of 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihy-dropyrimidine-4,6 (1H,5H)-dione.

Altowyan MS, Barakat A, Al-Majid AM, Ghabbour HA, Zarrouk A, Warad I.

BMC Chem. 2019 Feb 2;13(1):11. doi: 10.1186/s13065-019-0524-8. eCollection 2019 Dec.


Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase.

Altowyan MS, Barakat A, Al-Majid AM, Al-Ghulikah HA.

Molecules. 2019 Jun 25;24(12). pii: E2342. doi: 10.3390/molecules24122342.


Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study.

Al-Majid AM, Islam MS, Atef S, El-Senduny FF, Badria FA, Elshaier YAMM, Ali M, Barakat A, Motiur Rahman AFM.

Molecules. 2019 Apr 4;24(7). pii: E1332. doi: 10.3390/molecules24071332.


Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2-p53 interaction.

Barakat A, Islam MS, Ghawas HM, Al-Majid AM, El-Senduny FF, Badria FA, Elshaier YAMM, Ghabbour HA.

Bioorg Chem. 2019 May;86:598-608. doi: 10.1016/j.bioorg.2019.01.053. Epub 2019 Jan 31.


Complex Clonal Diversity of Staphylococcus aureus Nasal Colonization among Community Personnel, Healthcare Workers, and Clinical Students in the Eastern Province, Saudi Arabia.

El-Mahdy TS, Al-Agamy MH, Emara M, Barakat A, Goering RV.

Biomed Res Int. 2018 Dec 18;2018:4208762. doi: 10.1155/2018/4208762. eCollection 2018.


Synthesis of new thiazolo-pyrrolidine-(spirooxindole) tethered to 3-acylindole as anticancer agents.

Islam MS, Ghawas HM, El-Senduny FF, Al-Majid AM, Elshaier YAMM, Badria FA, Barakat A.

Bioorg Chem. 2019 Feb;82:423-430. doi: 10.1016/j.bioorg.2018.10.036. Epub 2018 Oct 23.


Unexpected formation of polymeric silver(I) complexes of azine-type ligand via self-assembly of Ag-salts with isatin oxamohydrazide.

Soliman SM, Albering JH, Barakat A.

R Soc Open Sci. 2018 Jul 25;5(7):180434. doi: 10.1098/rsos.180434. eCollection 2018 Jul.


Catalytic asymmetric synthesis of indole derivatives as novel α-glucosidase inhibitors in vitro.

Islam MS, Barakat A, Al-Majid AM, Ali M, Yousuf S, Iqbal Choudhary M, Khalil R, Ul-Haq Z.

Bioorg Chem. 2018 Sep;79:350-354. doi: 10.1016/j.bioorg.2018.05.004. Epub 2018 May 15.


Synthesis, Crystal Structure and DFT Studies of a New Dinuclear Ag(I)-Malonamide Complex.

Soliman SM, Barakat A, Islam MS, Ghabbour HA.

Molecules. 2018 Apr 11;23(4). pii: E888. doi: 10.3390/molecules23040888.


Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures.

Barakat A, Al-Majid AM, Al-Qahtany BM, Ali M, Teleb M, Al-Agamy MH, Naz S, Ul-Haq Z.

Chem Cent J. 2018 Mar 14;12(1):29. doi: 10.1186/s13065-018-0399-0.


Regio- and stereoselective synthesis of new spirooxindoles via 1,3-dipolar cycloaddition reaction: Anticancer and molecular docking studies.

Lotfy G, El Ashry ESH, Said MM, El Tamany ES, Abdel Aziz YM, Al-Dhfyan A, Al-Majid AM, Barakat A.

J Photochem Photobiol B. 2018 Mar;180:98-108. doi: 10.1016/j.jphotobiol.2018.01.026. Epub 2018 Jan 31.


Synthesis of thiobarbituric acid derivatives: In vitro α-glucosidase inhibition and molecular docking studies.

Barakat A, Ali M, Mohammed Al-Majid A, Yousuf S, Iqbal Choudhary M, Khalil R, Ul-Haq Z.

Bioorg Chem. 2017 Dec;75:99-105. doi: 10.1016/j.bioorg.2017.09.003. Epub 2017 Sep 12.


Organochlorine pesticides and polychlorinated biphenyls in sewage sludge from Egypt.

Barakat AO, Khairy MA, Mahmoud MR.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2017 Jul 3;52(8):750-756. doi: 10.1080/10934529.2017.1303313. Epub 2017 Apr 3.


Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking.

Lotfy G, Said MM, El Ashry ESH, El Tamany ESH, Al-Dhfyan A, Abdel Aziz YM, Barakat A.

Bioorg Med Chem. 2017 Feb 15;25(4):1514-1523. doi: 10.1016/j.bmc.2017.01.014. Epub 2017 Jan 16.


Synthesis of Pyrazole-Thiobarbituric Acid Derivatives: Antimicrobial Activity and Docking Studies.

Elshaier YA, Barakat A, Al-Qahtany BM, Al-Majid AM, Al-Agamy MH.

Molecules. 2016 Oct 9;21(10). pii: E1337.


Synthesis of pyrimidine-2,4,6-trione derivatives: Anti-oxidant, anti-cancer, α-glucosidase, β-glucuronidase inhibition and their molecular docking studies.

Barakat A, Islam MS, Al-Majid AM, Ghabbour HA, Yousuf S, Ashraf M, Shaikh NN, Iqbal Choudhary M, Khalil R, Ul-Haq Z.

Bioorg Chem. 2016 Oct;68:72-9. doi: 10.1016/j.bioorg.2016.07.009. Epub 2016 Jul 19.


Synthesis, spectral, thermal, crystal structure, Hirschfeld analysis of [bis(triamine)Cadimium(II)][Cadimum(IV)tetra-bromide] complexes and their thermolysis to CdO nanoparticles.

Warad I, Al-Rimawi F, Barakat A, Affouneh S, Shivalingegowda N, Lokanath NK, Abu-Reidah IM.

Chem Cent J. 2016 Jun 13;10:38. doi: 10.1186/s13065-016-0183-y. eCollection 2016.


3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model.

Ul-Haq Z, Ashraf S, Al-Majid AM, Barakat A.

Int J Mol Sci. 2016 Apr 30;17(5). pii: E657. doi: 10.3390/ijms17050657.


Synthesis of New Functionalized Indoles Based on Ethyl Indol-2-carboxylate.

Boraei AT, El Ashry el SH, Barakat A, Ghabbour HA.

Molecules. 2016 Mar 10;21(3):333. doi: 10.3390/molecules21030333.

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