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Items: 1 to 20 of 184

1.

Web Application for Quantification of Traumatic Brain Injury-Induced Cortical Lesions in Adult Mice.

Ciszek R, Andrade P, Tapiala J, Pitkänen A, Ndode-Ekane XE.

Neuroinformatics. 2019 Dec 4. doi: 10.1007/s12021-019-09444-9. [Epub ahead of print]

PMID:
31802356
2.

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.

Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A.

Int J Mol Sci. 2019 Oct 29;20(21). pii: E5395. doi: 10.3390/ijms20215395.

3.

Acute Downregulation of Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 after Experimental Traumatic Brain Injury.

Anwer M, Lara-Valderrabano L, Karttunen J, Ndode-Ekane XE, Puhakka N, Pitkänen A.

J Neurotrauma. 2019 Dec 5. doi: 10.1089/neu.2019.6739. [Epub ahead of print]

PMID:
31650880
4.

MRS Reveals Chronic Inflammation in T2w MRI-Negative Perilesional Cortex - A 6-Months Multimodal Imaging Follow-Up Study.

Yasmin A, Pitkänen A, Jokivarsi K, Poutiainen P, Gröhn O, Immonen R.

Front Neurosci. 2019 Aug 16;13:863. doi: 10.3389/fnins.2019.00863. eCollection 2019.

5.

Lateral fluid-percussion injury leads to pituitary atrophy in rats.

Anwer M, Immonen R, Hayward NMEA, Ndode-Ekane XE, Puhakka N, Gröhn O, Pitkänen A.

Sci Rep. 2019 Aug 14;9(1):11819. doi: 10.1038/s41598-019-48404-w.

6.

Biomarkers for epileptogenesis and its treatment.

Engel J Jr, Pitkänen A.

Neuropharmacology. 2019 Aug 1:107735. doi: 10.1016/j.neuropharm.2019.107735. [Epub ahead of print] Review.

PMID:
31377200
7.

Genotype and Injury Effect on the Expression of a Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 (SRPX2).

Anwer M, Bolkvadze T, Puhakka N, Ndode-Ekane XE, Pitkänen A.

Neuroscience. 2019 Sep 1;415:184-200. doi: 10.1016/j.neuroscience.2019.07.040. Epub 2019 Jul 27.

PMID:
31362033
8.

Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy.

Pitkänen A, Henshall DC, Cross JH, Guerrini R, Jozwiak S, Kokaia M, Simonato M, Sisodiya S, Mifsud J.

Epilepsia. 2019 Jul;60(7):1281-1292. doi: 10.1111/epi.16091. Epub 2019 Jun 18. Review.

PMID:
31211425
9.

Visualization of thalamic calcium influx with quantitative susceptibility mapping as a potential imaging biomarker for repeated mild traumatic brain injury.

Schweser F, Kyyriäinen J, Preda M, Pitkänen A, Toffolo K, Poulsen A, Donahue K, Levy B, Poulsen D.

Neuroimage. 2019 Oct 15;200:250-258. doi: 10.1016/j.neuroimage.2019.06.024. Epub 2019 Jun 12.

PMID:
31201986
10.

Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis.

Casillas-Espinosa PM, Andrade P, Santana-Gomez C, Paananen T, Smith G, Ali I, Ciszek R, Ndode-Ekane XE, Brady RD, Tohka J, Hudson MR, Perucca P, Braine EL, Immonen R, Puhakka N, Shultz SR, Jones NC, Staba RJ, Pitkänen A, O'Brien TJ.

Epilepsy Res. 2019 Oct;156:106131. doi: 10.1016/j.eplepsyres.2019.04.011. Epub 2019 Apr 27.

PMID:
31076256
11.

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis.

Santana-Gomez C, Andrade P, Hudson MR, Paananen T, Ciszek R, Smith G, Ali I, Rundle BK, Ndode-Ekane XE, Casillas-Espinosa PM, Immonen R, Puhakka N, Jones N, Brady RD, Perucca P, Shultz SR, Pitkänen A, O'Brien TJ, Staba R.

Epilepsy Res. 2019 Oct;156:106110. doi: 10.1016/j.eplepsyres.2019.03.008. Epub 2019 Mar 15.

PMID:
30981541
12.

Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies.

Karttunen J, Heiskanen M, Lipponen A, Poulsen D, Pitkänen A.

Int J Mol Sci. 2019 Mar 13;20(6). pii: E1259. doi: 10.3390/ijms20061259. Review.

13.

Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility.

Kyyriäinen J, Bolkvadze T, Koivisto H, Lipponen A, Pérez LO, Ekolle Ndode-Ekane X, Tanila H, Pitkänen A.

Epilepsy Res. 2019 Mar;151:67-74. doi: 10.1016/j.eplepsyres.2019.02.009. Epub 2019 Feb 25.

PMID:
30836238
14.

Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ndode-Ekane XE, Santana-Gomez C, Casillas-Espinosa PM, Ali I, Brady RD, Smith G, Andrade P, Immonen R, Puhakka N, Hudson MR, Braine EL, Shultz SR, Staba RJ, O'Brien TJ, Pitkänen A.

Epilepsy Res. 2019 Mar;151:7-16. doi: 10.1016/j.eplepsyres.2019.01.006. Epub 2019 Jan 18.

PMID:
30711714
15.
16.

Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis.

Immonen R, Smith G, Brady RD, Wright D, Johnston L, Harris NG, Manninen E, Salo R, Branch C, Duncan D, Cabeen R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Shultz SR, Andrade P, Puhakka N, Staba RJ, O'Brien TJ, Toga AW, Pitkänen A, Gröhn O.

Epilepsy Res. 2019 Feb;150:46-57. doi: 10.1016/j.eplepsyres.2019.01.001. Epub 2019 Jan 7.

PMID:
30641351
17.

Analytic Tools for Post-traumatic Epileptogenesis Biomarker Search in Multimodal Dataset of an Animal Model and Human Patients.

Duncan D, Barisano G, Cabeen R, Sepehrband F, Garner R, Braimah A, Vespa P, Pitkänen A, Law M, Toga AW.

Front Neuroinform. 2018 Dec 20;12:86. doi: 10.3389/fninf.2018.00086. eCollection 2018.

18.

Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ciszek R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Smith G, Puhakka N, Lapinlampi N, Andrade P, Kamnaksh A, Immonen R, Paananen T, Hudson MR, Brady RD, Shultz SR, O'Brien TJ, Staba RJ, Tohka J, Pitkänen A.

Epilepsy Res. 2019 Feb;150:17-26. doi: 10.1016/j.eplepsyres.2018.12.010. Epub 2018 Dec 27.

PMID:
30605864
19.

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs.

Karttunen J, Heiskanen M, Navarro-Ferrandis V, Das Gupta S, Lipponen A, Puhakka N, Rilla K, Koistinen A, Pitkänen A.

J Extracell Vesicles. 2018 Dec 18;8(1):1555410. doi: 10.1080/20013078.2018.1555410. eCollection 2019.

20.

Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis.

Kamnaksh A, Puhakka N, Ali I, Smith G, Aniceto R, McCullough J, Das Gupta S, Ndode-Ekane XE, Brady R, Casillas-Espinosa P, Hudson M, Santana-Gomez C, Immonen R, Abreu PA, Jones N, Shultz S, Staba RJ, O'Brien TJ, Agoston D, Pitkänen A.

Epilepsy Res. 2019 Jan;149:92-101. doi: 10.1016/j.eplepsyres.2018.11.009. Epub 2018 Nov 26.

PMID:
30553097

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