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Items: 13


Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes.

Yang D, Wijenayaka AR, Solomon LB, Pederson SM, Findlay DM, Kidd SP, Atkins GJ.

MBio. 2018 Apr 24;9(2). pii: e00415-18. doi: 10.1128/mBio.00415-18.


Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation.

Yang D, Anderson PH, Wijenayaka AR, Barratt KR, Triliana R, Stapledon CJM, Zhou H, Findlay DM, Morris HA, Atkins GJ.

J Steroid Biochem Mol Biol. 2018 Mar;177:83-90. doi: 10.1016/j.jsbmb.2017.09.005. Epub 2017 Sep 6.


Isolation of osteocytes from human trabecular bone.

Prideaux M, Schutz C, Wijenayaka AR, Findlay DM, Campbell DG, Solomon LB, Atkins GJ.

Bone. 2016 Jul;88:64-72. doi: 10.1016/j.bone.2016.04.017. Epub 2016 Apr 22.


Early response of the human SOST gene to stimulation by 1α,25-dihydroxyvitamin D3.

Wijenayaka AR, Prideaux M, Yang D, Morris HA, Findlay DM, Anderson PH, Atkins GJ.

J Steroid Biochem Mol Biol. 2016 Nov;164:369-373. doi: 10.1016/j.jsbmb.2015.12.006. Epub 2015 Dec 9.


1α,25-dihydroxyvitamin D3 stimulates human SOST gene expression and sclerostin secretion.

Wijenayaka AR, Yang D, Prideaux M, Ito N, Kogawa M, Anderson PH, Morris HA, Solomon LB, Loots GG, Findlay DM, Atkins GJ.

Mol Cell Endocrinol. 2015 Sep 15;413:157-67. doi: 10.1016/j.mce.2015.06.021. Epub 2015 Jun 23.


1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5.

Yang D, Turner AG, Wijenayaka AR, Anderson PH, Morris HA, Atkins GJ.

Mol Cell Endocrinol. 2015 Sep 5;412:140-7. doi: 10.1016/j.mce.2015.06.005. Epub 2015 Jun 6.


Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli.

Ito N, Wijenayaka AR, Prideaux M, Kogawa M, Ormsby RT, Evdokiou A, Bonewald LF, Findlay DM, Atkins GJ.

Mol Cell Endocrinol. 2015 Jan 5;399:208-18. doi: 10.1016/j.mce.2014.10.007. Epub 2014 Oct 16.


SaOS2 Osteosarcoma cells as an in vitro model for studying the transition of human osteoblasts to osteocytes.

Prideaux M, Wijenayaka AR, Kumarasinghe DD, Ormsby RT, Evdokiou A, Findlay DM, Atkins GJ.

Calcif Tissue Int. 2014 Aug;95(2):183-93. doi: 10.1007/s00223-014-9879-y. Epub 2014 Jun 12.


Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.

Kogawa M, Wijenayaka AR, Ormsby RT, Thomas GP, Anderson PH, Bonewald LF, Findlay DM, Atkins GJ.

J Bone Miner Res. 2013 Dec;28(12):2436-48. doi: 10.1002/jbmr.2003.


Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway.

Wijenayaka AR, Kogawa M, Lim HP, Bonewald LF, Findlay DM, Atkins GJ.

PLoS One. 2011;6(10):e25900. doi: 10.1371/journal.pone.0025900. Epub 2011 Oct 4.


Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.

Atkins GJ, Rowe PS, Lim HP, Welldon KJ, Ormsby R, Wijenayaka AR, Zelenchuk L, Evdokiou A, Findlay DM.

J Bone Miner Res. 2011 Jul;26(7):1425-36. doi: 10.1002/jbmr.345.


Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms.

Atkins GJ, Welldon KJ, Wijenayaka AR, Bonewald LF, Findlay DM.

Am J Physiol Cell Physiol. 2009 Dec;297(6):C1358-67. doi: 10.1152/ajpcell.00216.2009. Epub 2009 Aug 12.


Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts.

Vincent C, Findlay DM, Welldon KJ, Wijenayaka AR, Zheng TS, Haynes DR, Fazzalari NL, Evdokiou A, Atkins GJ.

J Bone Miner Res. 2009 Aug;24(8):1434-49. doi: 10.1359/jbmr.090305.

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