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Items: 1 to 20 of 41

1.

Cryptotanshinone from the Salvia miltiorrhiza Bunge Attenuates Ethanol-Induced Liver Injury by Activation of AMPK/SIRT1 and Nrf2 Signaling Pathways.

Nagappan A, Kim JH, Jung DY, Jung MH.

Int J Mol Sci. 2019 Dec 30;21(1). pii: E265. doi: 10.3390/ijms21010265.

2.

Role of Cannabinoid Receptor Type 1 in Insulin Resistance and Its Biological Implications.

Nagappan A, Shin J, Jung MH.

Int J Mol Sci. 2019 Apr 29;20(9). pii: E2109. doi: 10.3390/ijms20092109. Review.

3.

Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.

Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, Park C, Chang SH, Kim ND, Leem SH, Chang YC, Kwon TK, Cheong JH, Kim GS, Jung JM, Shin SC, Hong SC, Choi YH.

Phytother Res. 2019 May;33(5):1384-1393. doi: 10.1002/ptr.6329. Epub 2019 Mar 19.

PMID:
30887612
4.

Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2.

Kim JH, Jung DY, Nagappan A, Jung MH.

Sci Rep. 2018 Sep 13;8(1):13734. doi: 10.1038/s41598-018-31953-x.

5.

Gomisin N Alleviates Ethanol-Induced Liver Injury through Ameliorating Lipid Metabolism and Oxidative Stress.

Nagappan A, Jung DY, Kim JH, Lee H, Jung MH.

Int J Mol Sci. 2018 Sep 1;19(9). pii: E2601. doi: 10.3390/ijms19092601.

6.

Protective Effects of Gomisin N against Hepatic Cannabinoid Type 1 Receptor-Induced Insulin Resistance and Gluconeogenesis.

Nagappan A, Jung DY, Kim JH, Jung MH.

Int J Mol Sci. 2018 Mar 23;19(4). pii: E968. doi: 10.3390/ijms19040968.

7.

Lonicera japonica Thunb. Induces caspase-dependent apoptosis through death receptors and suppression of AKT in U937 human leukemic cells.

Park C, Lee WS, Han MH, Song KS, Hong SH, Nagappan A, Kim GY, Kim GS, Jung JM, Ryu CH, Shin SC, Hong SC, Choi YH.

Phytother Res. 2018 Mar;32(3):504-513. doi: 10.1002/ptr.5996. Epub 2017 Nov 29.

PMID:
29193390
8.

Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells.

Park KI, Park H, Nagappan A, Hong GE, Yumnam S, Lee HJ, Kim EH, Lee WS, Shin SC, Kim JA, Lee SJ, Ma JY, Min T, Heo JD, Kim GS.

Oncol Lett. 2017 Apr;13(4):2521-2530. doi: 10.3892/ol.2017.5771. Epub 2017 Feb 23.

9.

Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.

Nagappan A, Lee WS, Yun JW, Lu JN, Chang SH, Jeong JH, Kim GS, Jung JM, Hong SC.

PLoS One. 2017 Mar 29;12(3):e0174591. doi: 10.1371/journal.pone.0174591. eCollection 2017.

10.

Flavonoids Isolated from Flowers of Lonicera japonica Thunb. Inhibit Inflammatory Responses in BV2 Microglial Cells by Suppressing TNF-α and IL-β Through PI3K/Akt/NF-kb Signaling Pathways.

Han MH, Lee WS, Nagappan A, Hong SH, Jung JH, Park C, Kim HJ, Kim GY, Kim G, Jung JM, Ryu CH, Shin SC, Hong SC, Choi YH.

Phytother Res. 2016 Nov;30(11):1824-1832. doi: 10.1002/ptr.5688. Epub 2016 Aug 18.

PMID:
27534446
11.

Proteomic analysis of selective cytotoxic anticancer properties of flavonoids isolated from Citrus platymamma on A549 human lung cancer cells.

Nagappan A, Venkatarame Gowda Saralamma V, Hong GE, Lee HJ, Shin SC, Kim EH, Lee WS, Kim GS.

Mol Med Rep. 2016 Oct;14(4):3814-22. doi: 10.3892/mmr.2016.5666. Epub 2016 Aug 24.

PMID:
27573346
12.

Morin, a Flavonoid from Moraceae, Inhibits Cancer Cell Adhesion to Endothelial Cells and EMT by Downregulating VCAM1 and Ncadherin.

Lee J, Jin H, Lee WS, Nagappan A, Choi YH, Kim GS, Jung J, Ryu CH, Shin SC, Hong SC, Kim HJ.

Asian Pac J Cancer Prev. 2016;17(7):3071-5.

13.

Flavonoids isolated from Citrus platymamma induced G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells.

Nagappan A, Lee HJ, Saralamma VV, Park HS, Hong GE, Yumnam S, Raha S, Charles SN, Shin SC, Kim EH, Lee WS, Kim GS.

Oncol Lett. 2016 Aug;12(2):1394-1402. Epub 2016 Jun 28.

14.

Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells.

Han MH, Lee WS, Nagappan A, Kim HJ, Park C, Kim GY, Hong SH, Kim ND, Kim G, Ryu CH, Shin SC, Choi YH.

Oncol Rep. 2016 Jul;36(1):99-107. doi: 10.3892/or.2016.4778. Epub 2016 Apr 28.

15.

Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand.

Saralamma VV, Nagappan A, Hong GE, Lee HJ, Yumnam S, Raha S, Heo JD, Lee SJ, Lee WS, Kim EH, Kim GS.

Int J Mol Sci. 2015 Sep 18;16(9):22676-91. doi: 10.3390/ijms160922676.

16.

Flavonoids isolated from Citrus platymamma induce mitochondrial-dependent apoptosis in AGS cells by modulation of the PI3K/AKT and MAPK pathways.

Lee HJ, Nagappan A, Park HS, Hong GE, Yumnam S, Raha S, Saralamma VV, Lee WS, Kim EH, Kim GS.

Oncol Rep. 2015 Sep;34(3):1517-25. doi: 10.3892/or.2015.4122. Epub 2015 Jul 10.

PMID:
26165353
17.

Pachymic Acid Induces Apoptosis of EJ Bladder Cancer Cells by DR5 Up-Regulation, ROS Generation, Modulation of Bcl-2 and IAP Family Members.

Jeong JW, Lee WS, Go SI, Nagappan A, Baek JY, Lee JD, Lee SJ, Park C, Kim GY, Kim HJ, Kim GS, Kwon TK, Ryu CH, Shin SC, Choi YH.

Phytother Res. 2015 Oct;29(10):1516-24. doi: 10.1002/ptr.5402. Epub 2015 Jul 7.

PMID:
26148472
18.

The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells.

Hyun HB, Lee WS, Go SI, Nagappan A, Park C, Han MH, Hong SH, Kim G, Kim GY, Cheong J, Ryu CH, Shin SC, Choi YH.

Int J Oncol. 2015;46(6):2670-8. doi: 10.3892/ijo.2015.2967. Epub 2015 Apr 16.

PMID:
25892545
19.

Anthocyanins From the Fruit of Vitis coignetiae Pulliat Potentiate the Cisplatin Activity by Inhibiting PI3K/Akt Signaling Pathways in Human Gastric Cancer Cells.

Lu JN, Lee WS, Nagappan A, Chang SH, Choi YH, Kim HJ, Kim GS, Ryu CH, Shin SC, Jung JM, Hong SC.

J Cancer Prev. 2015 Mar;20(1):50-6. doi: 10.15430/JCP.2015.20.1.50.

20.

Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-κB activity in SW620 human colon cancer cells.

Lee WS, Yun JW, Nagappan A, Park HS, Lu JN, Kim HJ, Chang SH, Kim DC, Lee JH, Jung JM, Hong SC, Ha WS, Kim G.

Oncol Rep. 2015 Jun;33(6):2940-6. doi: 10.3892/or.2015.3890. Epub 2015 Mar 31.

PMID:
25845556

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