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Items: 1 to 20 of 114

1.

In Search of Predictors of Switching Between Erythropoiesis-Stimulating Agents in Clinical Practice: A Multi-Regional Cohort Study.

Ingrasciotta Y, Belleudi V, Trotta F, Addis A, Fontana A, Chinellato A, Ientile V, Tari DU, Roberto G, Pastorello M, Scondotto S, Cananzi P, Traversa G, Davoli M, Rossi M, Trifirò G; Italian Biosimilars Network (I-BioNetwork).

BioDrugs. 2019 Oct 8. doi: 10.1007/s40259-019-00385-y. [Epub ahead of print]

PMID:
31595485
2.

Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group.

Travelli C, Aprile S, Mattoteia D, Colombo G, Clemente N, Scanziani E, Terrazzino S, Alisi MA, Polenzani L, Grosa G, Genazzani AA, Tron GC, Galli U.

Eur J Med Chem. 2019 Aug 1;181:111576. doi: 10.1016/j.ejmech.2019.111576. [Epub ahead of print]

PMID:
31400709
3.

Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+-shuttling event.

Talmon M, Rossi S, Lim D, Pollastro F, Palattella G, Ruffinatti FA, Marotta P, Boldorini R, Genazzani AA, Fresu LG.

J Biol Chem. 2019 Aug 16;294(33):12472-12482. doi: 10.1074/jbc.RA119.007763. Epub 2019 Jun 27.

PMID:
31248983
4.

Effectiveness and Safety of Switching Originator and Biosimilar Epoetins in Patients with Chronic Kidney Disease in a Large-Scale Italian Cohort Study.

Belleudi V, Trotta F, Addis A, Ingrasciotta Y, Ientile V, Tari M, Gini R, Pastorello M, Scondotto S, Cananzi P, Traversa G, Davoli M, Trifirò G; Italian Biosimilar Network (ItaBioNet).

Drug Saf. 2019 Jun 21. doi: 10.1007/s40264-019-00845-y. [Epub ahead of print]

PMID:
31228010
5.

The INN global nomenclature of biological medicines: A continuous challenge.

Robertson JS, Chui WK, Genazzani AA, Malan SF, López de la Rica Manjavacas A, Mignot G, Thorpe R, Balocco R, Rizzi M.

Biologicals. 2019 Jul;60:15-23. doi: 10.1016/j.biologicals.2019.05.006. Epub 2019 May 23. Review.

6.

Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.

Pirali T, Galli U, Serafini M, Griglio A, Genazzani AA, Tron GC.

Methods Mol Biol. 2019;1987:207-221. doi: 10.1007/978-1-4939-9446-5_13.

PMID:
31028682
7.

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells.

Travelli C, Consonni FM, Sangaletti S, Storto M, Morlacchi S, Grolla AA, Galli U, Tron GC, Portararo P, Rimassa L, Pressiani T, Mazzone M, Trovato R, Ugel S, Bronte V, Tripodo C, Colombo MP, Genazzani AA, Sica A.

Cancer Res. 2019 Apr 15;79(8):1938-1951. doi: 10.1158/0008-5472.CAN-18-1544. Epub 2019 Feb 18.

PMID:
30777853
8.

Applications of Deuterium in Medicinal Chemistry.

Pirali T, Serafini M, Cargnin S, Genazzani AA.

J Med Chem. 2019 Jun 13;62(11):5276-5297. doi: 10.1021/acs.jmedchem.8b01808. Epub 2019 Jan 25.

PMID:
30640460
9.

Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model.

Rocchio F, Tapella L, Manfredi M, Chisari M, Ronco F, Ruffinatti FA, Conte E, Canonico PL, Sortino MA, Grilli M, Marengo E, Genazzani AA, Lim D.

Cell Death Dis. 2019 Jan 10;10(1):24. doi: 10.1038/s41419-018-1264-8.

10.

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.

Riva B, Griglio A, Serafini M, Cordero-Sanchez C, Aprile S, Di Paola R, Gugliandolo E, Alansary D, Biocotino I, Lim D, Grosa G, Galli U, Niemeyer B, Sorba G, Canonico PL, Cuzzocrea S, Genazzani AA, Pirali T.

J Med Chem. 2018 Nov 8;61(21):9756-9783. doi: 10.1021/acs.jmedchem.8b01512. Epub 2018 Oct 30.

PMID:
30347159
11.

Oxaliplatin induces pH acidification in dorsal root ganglia neurons.

Riva B, Dionisi M, Potenzieri A, Chiorazzi A, Cordero-Sanchez C, Rigolio R, Carozzi VA, Lim D, Cavaletti G, Marmiroli P, Distasi C, Genazzani AA.

Sci Rep. 2018 Oct 10;8(1):15084. doi: 10.1038/s41598-018-33508-6.

12.

Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures.

Lim D, Mapelli L, Canonico PL, Moccia F, Genazzani AA.

Int J Mol Sci. 2018 Sep 30;19(10). pii: E2997. doi: 10.3390/ijms19102997.

13.

Diagnostic accuracy of NUDT15 gene variants for thiopurine-induced leukopenia: a systematic review and meta-analysis.

Cargnin S, Genazzani AA, Canonico PL, Terrazzino S.

Pharmacol Res. 2018 Sep;135:102-111. doi: 10.1016/j.phrs.2018.07.021. Epub 2018 Jul 23.

PMID:
30048756
14.

NAMPT: A pleiotropic modulator of monocytes and macrophages.

Travelli C, Colombo G, Mola S, Genazzani AA, Porta C.

Pharmacol Res. 2018 Sep;135:25-36. doi: 10.1016/j.phrs.2018.06.022. Epub 2018 Jul 18. Review.

PMID:
30031171
15.

Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.

Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzalez-Rodriguez S, Butron L, Devesa I, Fernandez-Carvajal A, Pirali T, Ferrer-Montiel A.

J Med Chem. 2018 May 24;61(10):4436-4455. doi: 10.1021/acs.jmedchem.8b00109. Epub 2018 May 15.

PMID:
29722529
16.

TGF-β2 and TGF-β3 from cultured β-amyloid-treated or 3xTg-AD-derived astrocytes may mediate astrocyte-neuron communication.

Tapella L, Cerruti M, Biocotino I, Stevano A, Rocchio F, Canonico PL, Grilli M, Genazzani AA, Lim D.

Eur J Neurosci. 2018 Feb;47(3):211-221. doi: 10.1111/ejn.13819. Epub 2018 Jan 18.

PMID:
29283464
17.

Chemotherapy-induced peripheral neurotoxicity: management informed by pharmacogenetics.

Argyriou AA, Bruna J, Genazzani AA, Cavaletti G.

Nat Rev Neurol. 2017 Aug;13(8):492-504. doi: 10.1038/nrneurol.2017.88. Epub 2017 Jun 30. Review.

PMID:
28664909
18.

Synthesis and Degradation of Adenosine 5'-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases.

Amici A, Grolla AA, Del Grosso E, Bellini R, Bianchi M, Travelli C, Garavaglia S, Sorci L, Raffaelli N, Ruggieri S, Genazzani AA, Orsomando G.

Cell Chem Biol. 2017 May 18;24(5):553-564.e4. doi: 10.1016/j.chembiol.2017.03.010. Epub 2017 Apr 13.

19.

Pilot cohort study on the potential role of TCF7L2 rs7903146 on ischemic heart disease among non-diabetic kidney transplant recipients.

Quaglia M, Musetti C, Merlotti G, Genazzani AA, Cargnin S, Cena T, Cantaluppi V, Terrazzino S.

Clin Transplant. 2017 Jun;31(6). doi: 10.1111/ctr.12959. Epub 2017 Apr 17.

PMID:
28299838
20.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

Travelli C, Aprile S, Rahimian R, Grolla AA, Rogati F, Bertolotti M, Malagnino F, di Paola R, Impellizzeri D, Fusco R, Mercalli V, Massarotti A, Stortini G, Terrazzino S, Del Grosso E, Fakhfouri G, Troiani MP, Alisi MA, Grosa G, Sorba G, Canonico PL, Orsomando G, Cuzzocrea S, Genazzani AA, Galli U, Tron GC.

J Med Chem. 2017 Mar 9;60(5):1768-1792. doi: 10.1021/acs.jmedchem.6b01392. Epub 2017 Feb 22.

PMID:
28165742

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