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Items: 1 to 20 of 27


Inhibition of DNA Repair Mechanisms and Induction of Apoptosis in Triple Negative Breast Cancer Cells Expressing the Human Herpesvirus 6 U94.

Caccuri F, Sommariva M, Marsico S, Giordano F, Zani A, Giacomini A, Fraefel C, Balsari A, Caruso A.

Cancers (Basel). 2019 Jul 18;11(7). pii: E1006. doi: 10.3390/cancers11071006.


Quantification of 3D Brain Microangioarchitectures in an Animal Model of Krabbe Disease.

Righi M, Belleri M, Presta M, Giacomini A.

Int J Mol Sci. 2019 May 14;20(10). pii: E2384. doi: 10.3390/ijms20102384.


Circulating microRNAs and Their Role in Multiple Myeloma.

Federico C, Sacco A, Belotti A, Ribolla R, Cancelli V, Giacomini A, Ronca R, Chiarini M, Imberti L, Marini M, Rossi G, Presta M, Paiva B, Roccaro AM.

Noncoding RNA. 2019 May 2;5(2). pii: E37. doi: 10.3390/ncrna5020037. Review.


Vascular amounts and dispersion of caliber-classified vessels as key parameters to quantitate 3D micro-angioarchitectures in multiple myeloma experimental tumors.

Righi M, Locatelli SL, Carlo-Stella C, Presta M, Giacomini A.

Sci Rep. 2018 Nov 30;8(1):17520. doi: 10.1038/s41598-018-35788-4.


Long Pentraxin 3-Mediated Fibroblast Growth Factor Trapping Impairs Fibrosarcoma Growth.

Rodrigues PF, Matarazzo S, Maccarinelli F, Foglio E, Giacomini A, Silva Nunes JP, Presta M, Dias AAM, Ronca R.

Front Oncol. 2018 Nov 1;8:472. doi: 10.3389/fonc.2018.00472. eCollection 2018.


Future applications of FGF/FGFR inhibitors in cancer.

Ghedini GC, Ronca R, Presta M, Giacomini A.

Expert Rev Anticancer Ther. 2018 Sep;18(9):861-872. doi: 10.1080/14737140.2018.1491795. Epub 2018 Jul 2. Review.


Uptake Profiles of Human Serum Exosomes by Murine and Human Tumor Cells through Combined Use of Colloidal Nanoplasmonics and Flow Cytofluorimetric Analysis.

Busatto S, Giacomini A, Montis C, Ronca R, Bergese P.

Anal Chem. 2018 Jul 3;90(13):7855-7861. doi: 10.1021/acs.analchem.7b04374. Epub 2018 Jun 15.


Long pentraxin 3: A novel multifaceted player in cancer.

Giacomini A, Ghedini GC, Presta M, Ronca R.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):53-63. doi: 10.1016/j.bbcan.2017.11.004. Epub 2017 Nov 23. Review.


Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach.

Presta M, Chiodelli P, Giacomini A, Rusnati M, Ronca R.

Pharmacol Ther. 2017 Nov;179:171-187. doi: 10.1016/j.pharmthera.2017.05.013. Epub 2017 May 28. Review.


U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis.

Caccuri F, Ronca R, Laimbacher AS, Berenzi A, Steimberg N, Campilongo F, Mazzuca P, Giacomini A, Mazzoleni G, Benetti A, Caselli E, Presta M, Di Luca D, Fraefel C, Caruso A.

Oncotarget. 2017 Jul 4;8(27):44533-44549. doi: 10.18632/oncotarget.17817.


Synthesis, Structural Elucidation, and Biological Evaluation of NSC12, an Orally Available Fibroblast Growth Factor (FGF) Ligand Trap for the Treatment of FGF-Dependent Lung Tumors.

Castelli R, Giacomini A, Anselmi M, Bozza N, Vacondio F, Rivara S, Matarazzo S, Presta M, Mor M, Ronca R.

J Med Chem. 2016 May 26;59(10):4651-63. doi: 10.1021/acs.jmedchem.5b02021. Epub 2016 May 3.


Blocking the FGF/FGFR system as a "two-compartment" antiangiogenic/antitumor approach in cancer therapy.

Giacomini A, Chiodelli P, Matarazzo S, Rusnati M, Presta M, Ronca R.

Pharmacol Res. 2016 May;107:172-185. doi: 10.1016/j.phrs.2016.03.024. Epub 2016 Mar 22. Review.


Brain angioarchitecture and intussusceptive microvascular growth in a murine model of Krabbe disease.

Giacomini A, Ackermann M, Belleri M, Coltrini D, Nico B, Ribatti D, Konerding MA, Presta M, Righi M.

Angiogenesis. 2015 Oct;18(4):499-510. doi: 10.1007/s10456-015-9481-6. Epub 2015 Aug 27.


Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy.

Ronca R, Giacomini A, Di Salle E, Coltrini D, Pagano K, Ragona L, Matarazzo S, Rezzola S, Maiolo D, Torrella R, Moroni E, Mazzieri R, Escobar G, Mor M, Colombo G, Presta M.

Cancer Cell. 2015 Aug 10;28(2):225-39. doi: 10.1016/j.ccell.2015.07.002.


The potential of fibroblast growth factor/fibroblast growth factor receptor signaling as a therapeutic target in tumor angiogenesis.

Ronca R, Giacomini A, Rusnati M, Presta M.

Expert Opin Ther Targets. 2015;19(10):1361-77. doi: 10.1517/14728222.2015.1062475. Epub 2015 Jun 30. Review.


A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers.

Giacomini A, Matarazzo S, Pagano K, Ragona L, Rezzola S, Corsini M, Di Salle E, Presta M, Ronca R.

Oncotarget. 2015 May 30;6(15):13790-802.


Antiangiogenic effects of N6-isopentenyladenosine, an endogenous isoprenoid end product, mediated by AMPK activation.

Pisanti S, Picardi P, Ciaglia E, Margarucci L, Ronca R, Giacomini A, Malfitano AM, Casapullo A, Laezza C, Gazzerro P, Bifulco M.

FASEB J. 2014 Mar;28(3):1132-44. doi: 10.1096/fj.13-238238. Epub 2013 Nov 21.


Long pentraxin-3 inhibits epithelial-mesenchymal transition in melanoma cells.

Ronca R, Di Salle E, Giacomini A, Leali D, Alessi P, Coltrini D, Ravelli C, Matarazzo S, Ribatti D, Vermi W, Presta M.

Mol Cancer Ther. 2013 Dec;12(12):2760-71. doi: 10.1158/1535-7163.MCT-13-0487. Epub 2013 Oct 15.


Inhibition of angiogenesis by β-galactosylceramidase deficiency in globoid cell leukodystrophy.

Belleri M, Ronca R, Coltrini D, Nico B, Ribatti D, Poliani PL, Giacomini A, Alessi P, Marchesini S, Santos MB, Bongarzone ER, Presta M.

Brain. 2013 Sep;136(Pt 9):2859-75. doi: 10.1093/brain/awt215.


Sorafenib inhibits lymphoma xenografts by targeting MAPK/ERK and AKT pathways in tumor and vascular cells.

Carlo-Stella C, Locatelli SL, Giacomini A, Cleris L, Saba E, Righi M, Guidetti A, Gianni AM.

PLoS One. 2013 Apr 19;8(4):e61603. doi: 10.1371/journal.pone.0061603. Print 2013.

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