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Items: 20

1.

Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells.

Natarajan U, Venkatesan T, Radhakrishnan V, Samuel S, Rasappan P, Rathinavelu A.

Medicina (Kaunas). 2019 Jan 29;55(2). pii: E30. doi: 10.3390/medicina55020030.

2.

Differential Mechanisms of Cell Death Induced by HDAC Inhibitor SAHA and MDM2 Inhibitor RG7388 in MCF-7 Cells.

Natarajan U, Venkatesan T, Radhakrishnan V, Samuel S, Rathinavelu A.

Cells. 2018 Dec 22;8(1). pii: E8. doi: 10.3390/cells8010008.

3.

Focal Adhesion Kinase in Ovarian Cancer: A Potential Therapeutic Target for Platinum and Taxane-Resistant Tumors.

Levy A, Alhazzani K, Dondapati P, Alaseem A, Cheema K, Thallapureddy K, Kaur P, Alobid S, Rathinavelu A.

Curr Cancer Drug Targets. 2019;19(3):179-188. doi: 10.2174/1568009618666180706165222.

PMID:
29984656
4.

MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells.

Venkatesan T, Alaseem A, Chinnaiyan A, Dhandayuthapani S, Kanagasabai T, Alhazzani K, Dondapati P, Alobid S, Natarajan U, Schwartz R, Rathinavelu A.

Cells. 2018 May 10;7(5). pii: E41. doi: 10.3390/cells7050041.

5.

Anti-angiogenic and pro-apoptotic effects of a small-molecule JFD-WS in in vitro and breast cancer xenograft mouse models.

Rathinavelu A, Kanagasabai T, Dhandayuthapani S, Alhazzani K.

Oncol Rep. 2018 Apr;39(4):1711-1724. doi: 10.3892/or.2018.6256. Epub 2018 Feb 9.

PMID:
29436685
6.

Matrix Metalloproteinases: A challenging paradigm of cancer management.

Alaseem A, Alhazzani K, Dondapati P, Alobid S, Bishayee A, Rathinavelu A.

Semin Cancer Biol. 2019 Jun;56:100-115. doi: 10.1016/j.semcancer.2017.11.008. Epub 2017 Nov 16. Review.

PMID:
29155240
7.

Anti-cancer effects of F16: A novel vascular endothelial growth factor receptor-specific inhibitor.

Rathinavelu A, Alhazzani K, Dhandayuthapani S, Kanagasabai T.

Tumour Biol. 2017 Nov;39(11):1010428317726841. doi: 10.1177/1010428317726841.

PMID:
29130389
8.

Apoptosis Induction by Ocimum sanctum Extract in LNCaP Prostate Cancer Cells.

Dhandayuthapani S, Azad H, Rathinavelu A.

J Med Food. 2015 Jul;18(7):776-85. doi: 10.1089/jmf.2014.0008. Epub 2015 Feb 18.

PMID:
25692494
9.

Pro-angiogenic effects of MDM2 through HIF-1α and NF-κB mediated mechanisms in LNCaP prostate cancer cells.

Muthumani P, Alagarsamy K, Dhandayuthapani S, Venkatesan T, Rathinavelu A.

Mol Biol Rep. 2014 Aug;41(8):5533-41. doi: 10.1007/s11033-014-3430-0. Epub 2014 Jun 28.

PMID:
24972565
10.

Induction of apoptosis in HeLa cells via caspase activation by resveratrol and genistein.

Dhandayuthapani S, Marimuthu P, Hörmann V, Kumi-Diaka J, Rathinavelu A.

J Med Food. 2013 Feb;16(2):139-46. doi: 10.1089/jmf.2012.0141. Epub 2013 Jan 28.

PMID:
23356442
11.

Phycocyanin induces apoptosis and enhances the effect of topotecan on prostate cell line LNCaP.

Gantar M, Dhandayuthapani S, Rathinavelu A.

J Med Food. 2012 Dec;15(12):1091-5. doi: 10.1089/jmf.2012.0123. Epub 2012 Nov 7.

PMID:
23134462
12.

Anticancer activities of genistein-topotecan combination in prostate cancer cells.

Hörmann V, Kumi-Diaka J, Durity M, Rathinavelu A.

J Cell Mol Med. 2012 Nov;16(11):2631-6. doi: 10.1111/j.1582-4934.2012.01576.x.

13.

Bromelain-induced apoptosis in GI-101A breast cancer cells.

Dhandayuthapani S, Perez HD, Paroulek A, Chinnakkannu P, Kandalam U, Jaffe M, Rathinavelu A.

J Med Food. 2012 Apr;15(4):344-9. doi: 10.1089/jmf.2011.0145. Epub 2011 Dec 22.

PMID:
22191568
14.

A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells.

Rathinavelu A, Narasimhan M, Muthumani P.

J Cell Mol Med. 2012 Aug;16(8):1750-7. doi: 10.1111/j.1582-4934.2011.01472.x.

15.

Treatment of ovarian cancer cells with nutlin-3 and resveratrol combination leads to apoptosis via caspase activation.

Marimuthu P, Kaur K, Kandalam U, Jasani V, Bukhari N, Nguyen M, Abdul A, Pervez FF, Rathinavelu A.

J Med Food. 2011 Jan-Feb;14(1-2):46-52. doi: 10.1089/jmf.2009.0270. Epub 2010 Dec 27.

PMID:
21186985
16.

Identification of HDM2 as a regulator of VEGF expression in cancer cells.

Narasimhan M, Rose R, Ramakrishnan R, Zell JA, Rathinavelu A.

Life Sci. 2008 Jun 20;82(25-26):1231-41. doi: 10.1016/j.lfs.2008.04.004. Epub 2008 May 27.

PMID:
18504050
17.

Detection of HDM2 and VEGF co-expression in cancer cell lines: novel effect of HDM2 antisense treatment on VEGF expression.

Narasimhan M, Rose R, Karthikeyan M, Rathinavelu A.

Life Sci. 2007 Oct 13;81(17-18):1362-72. Epub 2007 Sep 9.

PMID:
17931661
18.

SiRNA drug delivery by biodegradable polymeric nanoparticles.

Yuan X, Li L, Rathinavelu A, Hao J, Narasimhan M, He M, Heitlage V, Tam L, Viqar S, Salehi M.

J Nanosci Nanotechnol. 2006 Sep-Oct;6(9-10):2821-8.

PMID:
17048488
19.

Identification of novel angiogenesis inhibitors.

Sridhar J, Akula N, Sivanesan D, Narasimhan M, Rathinavelu A, Pattabiraman N.

Bioorg Med Chem Lett. 2005 Sep 15;15(18):4125-9.

PMID:
15993586
20.

Regulation of mdm2 mRNA expression in human breast tumor-derived GI-101A cells.

Zell JA, Ramakrishnan R, Rathinavelu A.

Life Sci. 2002 Oct 4;71(20):2331-9.

PMID:
12231395

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