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Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1.

D'Alterio C, Buoncervello M, IeranĂ² C, Napolitano M, Portella L, Rea G, Barbieri A, Luciano A, Scognamiglio G, Tatangelo F, Anniciello AM, Monaco M, Cavalcanti E, Maiolino P, Romagnoli G, Arra C, Botti G, Gabriele L, Scala S.

J Exp Clin Cancer Res. 2019 Oct 28;38(1):432. doi: 10.1186/s13046-019-1420-8.


Shining a Light on the Effects of the Combination of (-)-Epigallocatechin-3-gallate and Tapentadol on the Growth of Human Triple-negative Breast Cancer Cells.

Bimonte S, Cascella M, Barbieri A, Arra C, Cuomo A.

In Vivo. 2019 Sep-Oct;33(5):1463-1468. doi: 10.21873/invivo.11625.


The effects of the use of platelet-rich plasma gel on local recurrence in an animal model of human fibrosarcoma.

Barbieri A, Bimonte S, Loquercio G, Rea D, Cascella M, Anniciello A, Luciano A, Palma G, Di Costanzo G, Rosa A, Giuliano P, Arra C.

Infect Agent Cancer. 2019 Aug 28;14:21. doi: 10.1186/s13027-019-0237-6. eCollection 2019.


Dissecting the prevention of estrogen-dependent breast carcinogenesis through Nrf2-dependent and independent mechanisms.

Giudice A, Barbieri A, Bimonte S, Cascella M, Cuomo A, Crispo A, D'Arena G, Galdiero M, Della Pepa ME, Botti G, Caraglia M, Capunzo M, Arra C, Montella M.

Onco Targets Ther. 2019 Jun 24;12:4937-4953. doi: 10.2147/OTT.S183192. eCollection 2019. Review.


CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells.

IeranĂ² C, D'Alterio C, Giarra S, Napolitano M, Rea G, Portella L, Santagata A, Trotta AM, Barbieri A, Campani V, Luciano A, Arra C, Anniciello AM, Botti G, Mayol L, De Rosa G, Pacelli R, Scala S.

Cell Death Dis. 2019 Jul 22;10(8):562. doi: 10.1038/s41419-019-1796-6.


Naloxone Counteracts the Promoting Tumor Growth Effects Induced by Morphine in an Animal Model of Triple-negative Breast Cancer.

Bimonte S, Barbieri A, Cascella M, Rea D, Palma G, Luciano A, Forte CA, Cuomo A, Arra C.

In Vivo. 2019 May-Jun;33(3):821-825. doi: 10.21873/invivo.11545.


Dissecting the roles of thymoquinone on the prevention and the treatment of hepatocellular carcinoma: an overview on the current state of knowledge.

Bimonte S, Albino V, Barbieri A, Tamma ML, Nasto A, Palaia R, Molino C, Bianco P, Vitale A, Schiano R, Giudice A, Cascella M.

Infect Agent Cancer. 2019 Apr 16;14:10. doi: 10.1186/s13027-019-0226-9. eCollection 2019. Review.


Dual Oncogenic/Anti-Oncogenic Role of PATZ1 in FRTL5 Rat Thyroid Cells Transformed by the Ha-RasV12 Oncogene.

Vitiello M, Palma G, Monaco M, Bello AM, Camorani S, Francesca P, Rea D, Barbieri A, Chiappetta G, Vita G, Cerchia L, Arra C, Fedele M.

Genes (Basel). 2019 Feb 9;10(2). pii: E127. doi: 10.3390/genes10020127.


A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.

Mele L, Paino F, Papaccio F, Regad T, Boocock D, Stiuso P, Lombardi A, Liccardo D, Aquino G, Barbieri A, Arra C, Coveney C, La Noce M, Papaccio G, Caraglia M, Tirino V, Desiderio V.

Cell Death Dis. 2018 May 1;9(5):572. doi: 10.1038/s41419-018-0635-5.


Cardiotoxic effects of the novel approved anti-ErbB2 agents and reverse cardioprotective effects of ranolazine.

De Lorenzo C, Paciello R, Riccio G, Rea D, Barbieri A, Coppola C, Maurea N.

Onco Targets Ther. 2018 Apr 19;11:2241-2250. doi: 10.2147/OTT.S157294. eCollection 2018.


Microbiota effects on cancer: from risks to therapies.

Rea D, Coppola G, Palma G, Barbieri A, Luciano A, Del Prete P, Rossetti S, Berretta M, Facchini G, PerdonĂ  S, Turco MC, Arra C.

Oncotarget. 2018 Apr 3;9(25):17915-17927. doi: 10.18632/oncotarget.24681. eCollection 2018 Apr 3. Review.


RANTES and IL-6 cooperate in inducing a more aggressive phenotype in breast cancer cells.

Gallo M, Frezzetti D, Roma C, Chicchinelli N, Barbieri A, Arra C, Scognamiglio G, Botti G, De Luca A, Normanno N.

Oncotarget. 2018 Apr 3;9(25):17543-17553. doi: 10.18632/oncotarget.24784. eCollection 2018 Apr 3.


Preeclamptic plasma stimulates the expression of miRNAs, leading to a decrease in endothelin-1 production in endothelial cells.

Caldeira-Dias M, Luizon MR, Deffune E, Tanus-Santos JE, Freire PP, Carvalho RF, Bettiol H, Cardoso VC, Antonio Barbieri M, Cavalli RC, Sandrim VC.

Pregnancy Hypertens. 2018 Apr;12:75-81. doi: 10.1016/j.preghy.2018.03.001. Epub 2018 Mar 27.


Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease.

Cascella M, Bimonte S, Barbieri A, Del Vecchio V, Muzio MR, Vitale A, Benincasa G, Ferriello AB, Azzariti A, Arra C, Cuomo A.

Front Aging Neurosci. 2018 Feb 9;10:16. doi: 10.3389/fnagi.2018.00016. eCollection 2018. Review.


Inhibition of tumor growth by cancer vaccine combined with metronomic chemotherapy and anti-PD-1 in a pre-clinical setting.

Petrizzo A, Mauriello A, Luciano A, Rea D, Barbieri A, Arra C, Maiolino P, Tornesello M, Gigantino V, Botti G, Ciliberto G, Buonaguro FM, Tagliamonte M, Buonaguro L.

Oncotarget. 2017 Dec 8;9(3):3576-3589. doi: 10.18632/oncotarget.23181. eCollection 2018 Jan 9.


The effects of naloxone on human breast cancer progression: in vitro and in vivo studies on MDA.MB231 cells.

Bimonte S, Barbieri A, Cascella M, Rea D, Palma G, Del Vecchio V, Forte CA, Del Prato F, Arra C, Cuomo A.

Onco Targets Ther. 2018 Jan 3;11:185-191. doi: 10.2147/OTT.S145780. eCollection 2018.


Dissecting the mechanisms and molecules underlying the potential carcinogenicity of red and processed meat in colorectal cancer (CRC): an overview on the current state of knowledge.

Cascella M, Bimonte S, Barbieri A, Del Vecchio V, Caliendo D, Schiavone V, Fusco R, Granata V, Arra C, Cuomo A.

Infect Agent Cancer. 2018 Jan 15;13:3. doi: 10.1186/s13027-018-0174-9. eCollection 2018. Review.


Management of QT prolongation induced by anti-cancer drugs: Target therapy and old agents. Different algorithms for different drugs.

Coppola C, Rienzo A, Piscopo G, Barbieri A, Arra C, Maurea N.

Cancer Treat Rev. 2018 Feb;63:135-143. doi: 10.1016/j.ctrv.2017.11.009. Epub 2017 Dec 6. Review.


HMGA2 cooperates with either p27kip1 deficiency or Cdk4R24C mutation in pituitary tumorigenesis.

Fedele M, Paciello O, De Biase D, Monaco M, Chiappetta G, Vitiello M, Barbieri A, Rea D, Luciano A, Papparella S, Arra C, Fusco A.

Cell Cycle. 2018;17(5):580-588. doi: 10.1080/15384101.2017.1403682. Epub 2018 Jan 30.


Enhanced Drug Delivery into Cell Cytosol via Glycoprotein H-Derived Peptide Conjugated Nanoemulsions.

Fotticchia T, Vecchione R, Scognamiglio PL, Guarnieri D, Calcagno V, Di Natale C, Attanasio C, De Gregorio M, Di Cicco C, Quagliariello V, Maurea N, Barbieri A, Arra C, Raiola L, Iaffaioli RV, Netti PA.

ACS Nano. 2017 Oct 24;11(10):9802-9813. doi: 10.1021/acsnano.7b03058. Epub 2017 Aug 28.


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