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Items: 1 to 20 of 222

1.

Histone Deacetylases Contribute to Excitotoxicity-Triggered Degeneration of Retinal Ganglion Cells In Vivo.

Schlüter A, Aksan B, Fioravanti R, Valente S, Mai A, Mauceri D.

Mol Neurobiol. 2019 Jun 3. doi: 10.1007/s12035-019-01658-x. [Epub ahead of print]

PMID:
31161423
2.

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.

Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S.

Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8.

3.

α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors.

Nocentini A, Lucidi A, Perut F, Massa A, Tomaselli D, Gratteri P, Baldini N, Rotili D, Mai A, Supuran CT.

ACS Med Chem Lett. 2019 Feb 19;10(4):661-665. doi: 10.1021/acsmedchemlett.9b00023. eCollection 2019 Apr 11.

PMID:
30996814
4.

Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.

Stazi G, Fioravanti R, Mai A, Mattevi A, Valente S.

Curr Opin Chem Biol. 2019 Apr 12;50:89-100. doi: 10.1016/j.cbpa.2019.03.002. [Epub ahead of print] Review.

PMID:
30986654
5.

Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells.

Sirotkin AV, Adamcova E, Rotili D, Mai A, Mlyncek M, Mansour L, Alwasel S, Harrath AH.

Eur J Pharmacol. 2019 Jul 5;854:70-78. doi: 10.1016/j.ejphar.2019.03.048. Epub 2019 Apr 5.

PMID:
30959047
6.

The emerging role of epigenetics in human autoimmune disorders.

Mazzone R, Zwergel C, Artico M, Taurone S, Ralli M, Greco A, Mai A.

Clin Epigenetics. 2019 Feb 26;11(1):34. doi: 10.1186/s13148-019-0632-2. Review.

7.

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells.

Mattioli E, Andrenacci D, Mai A, Valente S, Robijns J, De Vos WH, Capanni C, Lattanzi G.

Front Cell Dev Biol. 2019 Jan 31;7:6. doi: 10.3389/fcell.2019.00006. eCollection 2019.

8.

Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells.

Was H, Krol SK, Rotili D, Mai A, Wojtas B, Kaminska B, Maleszewska M.

Clin Epigenetics. 2019 Jan 17;11(1):11. doi: 10.1186/s13148-018-0598-5.

9.

Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat.

Atehortua-Martinez LA, Masniere C, Campolongo P, Chasseigneaux S, Callebert J, Zwergel C, Mai A, Laplanche JL, Chen H, Etheve-Quelquejeu M, Mégarbane B, Benturquia N.

J Psychopharmacol. 2019 Mar;33(3):392-405. doi: 10.1177/0269881118822151. Epub 2019 Jan 15.

PMID:
30644332
10.

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila.

Guida MC, Birse RT, Dall'Agnese A, Toto PC, Diop SB, Mai A, Adams PD, Puri PL, Bodmer R.

Nat Commun. 2019 Jan 14;10(1):193. doi: 10.1038/s41467-018-08128-3.

11.

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Stazi G, Battistelli C, Piano V, Mazzone R, Marrocco B, Marchese S, Louie SM, Zwergel C, Antonini L, Patsilinakos A, Ragno R, Viviano M, Sbardella G, Ciogli A, Fabrizi G, Cirilli R, Strippoli R, Marchetti A, Tripodi M, Nomura DK, Mattevi A, Mai A, Valente S.

Eur J Med Chem. 2019 Feb 1;163:722-735. doi: 10.1016/j.ejmech.2018.11.050. Epub 2018 Nov 28.

PMID:
30576903
12.

Application of Small Epigenetic Modulators in Pediatric Medulloblastoma.

Zwergel C, Romanelli A, Stazi G, Besharat ZM, Catanzaro G, Tafani M, Valente S, Mai A.

Front Pediatr. 2018 Dec 3;6:370. doi: 10.3389/fped.2018.00370. eCollection 2018. Review.

13.

Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones.

Nawrozkij MB, Forgione M, Yablokov AS, Lucidi A, Tomaselli D, Patsilinakos A, Panella C, Hailu GS, Kirillov IA, Badia R, Riveira-Muñoz E, Crespan E, Armijos Rivera JI, Cirilli R, Ragno R, Esté JA, Maga G, Mai A, Rotili D.

J Med Chem. 2019 Jan 24;62(2):604-621. doi: 10.1021/acs.jmedchem.8b01238. Epub 2018 Dec 20.

PMID:
30525601
14.

EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers.

Papale M, Ferretti E, Battaglia G, Bellavia D, Mai A, Tafani M.

Front Pediatr. 2018 Nov 19;6:328. doi: 10.3389/fped.2018.00328. eCollection 2018. Review.

15.

Identification of novel quinazoline derivatives as potent antiplasmodial agents.

Bouchut A, Rotili D, Pierrot C, Valente S, Lafitte S, Schultz J, Hoglund U, Mazzone R, Lucidi A, Fabrizi G, Pechalrieu D, Arimondo PB, Skinner-Adams TS, Chua MJ, Andrews KT, Mai A, Khalife J.

Eur J Med Chem. 2019 Jan 1;161:277-291. doi: 10.1016/j.ejmech.2018.10.041. Epub 2018 Oct 17.

PMID:
30366254
16.

Six Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone Compounds.

Fioravanti R, Stazi G, Zwergel C, Valente S, Mai A.

Chem Rec. 2018 Dec;18(12):1818-1832. doi: 10.1002/tcr.201800091. Epub 2018 Oct 19. Review.

PMID:
30338896
17.

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.

Iachettini S, Trisciuoglio D, Rotili D, Lucidi A, Salvati E, Zizza P, Di Leo L, Del Bufalo D, Ciriolo MR, Leonetti C, Steegborn C, Mai A, Rizzo A, Biroccio A.

Cell Death Dis. 2018 Sep 24;9(10):996. doi: 10.1038/s41419-018-1065-0.

18.

Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS.

Mattioli E, Andrenacci D, Garofalo C, Prencipe S, Scotlandi K, Remondini D, Gentilini D, Di Blasio AM, Valente S, Scarano E, Cicchilitti L, Piaggio G, Mai A, Lattanzi G.

Aging Cell. 2018 Oct;17(5):e12824. doi: 10.1111/acel.12824. Epub 2018 Aug 15. Erratum in: Aging Cell. 2018 Dec;17(6):e12885.

19.

Correction to 'Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells'.

Mellini P, Marrocco B, Borovika D, Polletta L, Carnevale I, Saladini S, Stazi G, Zwergel C, Trapencieris P, Ferretti E, Tafani M, Valente S, Mai A.

Philos Trans R Soc Lond B Biol Sci. 2018 Sep 19;373(1755). pii: 20180305. doi: 10.1098/rstb.2018.0305. No abstract available.

20.

Epigenetic metalloenzymes.

Blanquart C, Linot C, Cartron PF, Tomaselli D, Mai A, Bertrand P.

Curr Med Chem. 2018 Jul 5. doi: 10.2174/0929867325666180706105903. [Epub ahead of print]

PMID:
29984644

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