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Items: 11


Salinomycin Derivatives Kill Breast Cancer Stem Cells via Lysosomal Iron Targeting.

Versini A, Colombeau L, Hienzsch A, Gaillet C, Retailleau P, Debieu S, Müller S, Cañeque T, Rodriguez R.

Chemistry. 2020 Feb 21. doi: 10.1002/chem.202000335. [Epub ahead of print]


Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer.

Cardinale J, Martin R, Remde Y, Schäfer M, Hienzsch A, Hübner S, Zerges AM, Marx H, Hesse R, Weber K, Smits R, Hoepping A, Müller M, Neels OC, Kopka K.

Pharmaceuticals (Basel). 2017 Sep 27;10(4). pii: E77. doi: 10.3390/ph10040077.


Salinomycin kills cancer stem cells by sequestering iron in lysosomes.

Mai TT, Hamaï A, Hienzsch A, Cañeque T, Müller S, Wicinski J, Cabaud O, Leroy C, David A, Acevedo V, Ryo A, Ginestier C, Birnbaum D, Charafe-Jauffret E, Codogno P, Mehrpour M, Rodriguez R.

Nat Chem. 2017 Oct;9(10):1025-1033. doi: 10.1038/nchem.2778. Epub 2017 May 16.


Click chemistry enables preclinical evaluation of targeted epigenetic therapies.

Tyler DS, Vappiani J, Cañeque T, Lam EYN, Ward A, Gilan O, Chan YC, Hienzsch A, Rutkowska A, Werner T, Wagner AJ, Lugo D, Gregory R, Ramirez Molina C, Garton N, Wellaway CR, Jackson S, MacPherson L, Figueiredo M, Stolzenburg S, Bell CC, House C, Dawson SJ, Hawkins ED, Drewes G, Prinjha RK, Rodriguez R, Grandi P, Dawson MA.

Science. 2017 Jun 30;356(6345):1397-1401. doi: 10.1126/science.aal2066. Epub 2017 Jun 15.


An iron hand over cancer stem cells.

Hamaï A, Cañeque T, Müller S, Mai TT, Hienzsch A, Ginestier C, Charafe-Jauffret E, Codogno P, Mehrpour M, Rodriguez R.

Autophagy. 2017 Aug 3;13(8):1465-1466. doi: 10.1080/15548627.2017.1327104. Epub 2017 Jun 14.


Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.

Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, Gruber S, Wilson TC, Taylor NJ, Cailly T, Schedler M, Collier TL, Passchier J, Smits R, Mollitor J, Hoepping A, Mueller M, Genicot C, Mercier J, Gouverneur V.

Chem Commun (Camb). 2016 Jun 28;52(54):8361-4. doi: 10.1039/c6cc03295h.


Total synthesis of the hypermodified RNA bases wybutosine and hydroxywybutosine and their quantification together with other modified RNA bases in plant materials.

Hienzsch A, Deiml C, Reiter V, Carell T.

Chemistry. 2013 Mar 25;19(13):4244-8. doi: 10.1002/chem.201204209. Epub 2013 Feb 18.


Isotope-based analysis of modified tRNA nucleosides correlates modification density with translational efficiency.

Brandmayr C, Wagner M, Brückl T, Globisch D, Pearson D, Kneuttinger AC, Reiter V, Hienzsch A, Koch S, Thoma I, Thumbs P, Michalakis S, Müller M, Biel M, Carell T.

Angew Chem Int Ed Engl. 2012 Oct 29;51(44):11162-5. doi: 10.1002/anie.201203769. Epub 2012 Oct 4.


Structure and function of noncanonical nucleobases.

Carell T, Brandmayr C, Hienzsch A, Müller M, Pearson D, Reiter V, Thoma I, Thumbs P, Wagner M.

Angew Chem Int Ed Engl. 2012 Jul 16;51(29):7110-31. doi: 10.1002/anie.201201193. Epub 2012 Jun 28. Review.


Systems-based analysis of modified tRNA bases.

Globisch D, Pearson D, Hienzsch A, Brückl T, Wagner M, Thoma I, Thumbs P, Reiter V, Kneuttinger AC, Müller M, Sieber SA, Carell T.

Angew Chem Int Ed Engl. 2011 Oct 4;50(41):9739-42. doi: 10.1002/anie.201103229. Epub 2011 Aug 31. No abstract available.


LC-MS based quantification of 2'-ribosylated nucleosides Ar(p) and Gr(p) in tRNA.

Pearson D, Hienzsch A, Wagner M, Globisch D, Reiter V, Özden D, Carell T.

Chem Commun (Camb). 2011 May 14;47(18):5196-8. doi: 10.1039/c1cc11011j. Epub 2011 Mar 29.


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