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Items: 17


Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection.

Khakpoor A, Ni Y, Chen A, Ho ZZ, Oei V, Yang N, Giri R, Chow JX, Tan AT, Kennedy PT, Maini M, Urban S, Bertoletti A.

J Virol. 2019 Feb 5;93(4). pii: e01457-18. doi: 10.1128/JVI.01457-18. Print 2019 Feb 15.


Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3.

Koh S, Kah J, Tham CYL, Yang N, Ceccarello E, Chia A, Chen M, Khakpoor A, Pavesi A, Tan AT, Dandri M, Bertoletti A.

Gastroenterology. 2018 Jul;155(1):180-193.e6. doi: 10.1053/j.gastro.2018.03.027. Epub 2018 Mar 14.


A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors.

Pavesi A, Tan AT, Koh S, Chia A, Colombo M, Antonecchia E, Miccolis C, Ceccarello E, Adriani G, Raimondi MT, Kamm RD, Bertoletti A.

JCI Insight. 2017 Jun 15;2(12). pii: 89762. doi: 10.1172/jci.insight.89762. eCollection 2017 Jun 15.


Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease.

Tan-Garcia A, Wai LE, Zheng D, Ceccarello E, Jo J, Banu N, Khakpoor A, Chia A, Tham CYL, Tan AT, Hong M, Keng CT, Rivino L, Tan KC, Lee KH, Lim SG, Newell EW, Pavelka N, Chen J, Ginhoux F, Chen Q, Bertoletti A, Dutertre CA.

J Hepatol. 2017 Sep;67(3):490-500. doi: 10.1016/j.jhep.2017.04.023. Epub 2017 May 5.


Microfluidic models for adoptive cell-mediated cancer immunotherapies.

Adriani G, Pavesi A, Tan AT, Bertoletti A, Thiery JP, Kamm RD.

Drug Discov Today. 2016 Sep;21(9):1472-1478. doi: 10.1016/j.drudis.2016.05.006. Epub 2016 May 13. Review.


Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection.

Ng OW, Chia A, Tan AT, Jadi RS, Leong HN, Bertoletti A, Tan YJ.

Vaccine. 2016 Apr 12;34(17):2008-14. doi: 10.1016/j.vaccine.2016.02.063. Epub 2016 Mar 5.


Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver.

Jo J, Tan AT, Ussher JE, Sandalova E, Tang XZ, Tan-Garcia A, To N, Hong M, Chia A, Gill US, Kennedy PT, Tan KC, Lee KH, De Libero G, Gehring AJ, Willberg CB, Klenerman P, Bertoletti A.

PLoS Pathog. 2014 Jun 26;10(6):e1004210. doi: 10.1371/journal.ppat.1004210. eCollection 2014 Jun.


Immunoprevalence and immunodominance of HLA-Cw*0801-restricted T cell response targeting the hepatitis B virus envelope transmembrane region.

Tan AT, Sodsai P, Chia A, Moreau E, Chng MH, Tham CY, Ho ZZ, Banu N, Hirankarn N, Bertoletti A.

J Virol. 2014 Jan;88(2):1332-41. doi: 10.1128/JVI.02600-13. Epub 2013 Nov 13.


Defining CD8+ T cell determinants during human viral infection in populations of Asian ethnicity.

Rivino L, Tan AT, Chia A, Kumaran EA, Grotenbreg GM, MacAry PA, Bertoletti A.

J Immunol. 2013 Oct 15;191(8):4010-9. doi: 10.4049/jimmunol.1301507. Epub 2013 Sep 20.


Reduction of HBV replication prolongs the early immunological response to IFNα therapy.

Tan AT, Hoang LT, Chin D, Rasmussen E, Lopatin U, Hart S, Bitter H, Chu T, Gruenbaum L, Ravindran P, Zhong H, Gane E, Lim SG, Chow WC, Chen PJ, Petric R, Bertoletti A, Hibberd ML.

J Hepatol. 2014 Jan;60(1):54-61. doi: 10.1016/j.jhep.2013.08.020. Epub 2013 Aug 29.


IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.

Tang XZ, Jo J, Tan AT, Sandalova E, Chia A, Tan KC, Lee KH, Gehring AJ, De Libero G, Bertoletti A.

J Immunol. 2013 Apr 1;190(7):3142-52. doi: 10.4049/jimmunol.1203218. Epub 2013 Feb 27.


Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases.

Chang CX, Tan AT, Or MY, Toh KY, Lim PY, Chia AS, Froesig TM, Nadua KD, Oh HL, Leong HN, Hadrup SR, Gehring AJ, Tan YJ, Bertoletti A, Grotenbreg GM.

Eur J Immunol. 2013 Apr;43(4):1109-20. doi: 10.1002/eji.201243088. Epub 2013 Feb 14.


Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B.

Kennedy PTF, Sandalova E, Jo J, Gill U, Ushiro-Lumb I, Tan AT, Naik S, Foster GR, Bertoletti A.

Gastroenterology. 2012 Sep;143(3):637-645. doi: 10.1053/j.gastro.2012.06.009. Epub 2012 Jun 15.


Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans.

Sandalova E, Laccabue D, Boni C, Tan AT, Fink K, Ooi EE, Chua R, Shafaeddin Schreve B, Ferrari C, Bertoletti A.

PLoS Pathog. 2010 Aug 19;6(8):e1001051. doi: 10.1371/journal.ppat.1001051.


A longitudinal analysis of innate and adaptive immune profile during hepatic flares in chronic hepatitis B.

Tan AT, Koh S, Goh W, Zhe HY, Gehring AJ, Lim SG, Bertoletti A.

J Hepatol. 2010 Mar;52(3):330-9. doi: 10.1016/j.jhep.2009.12.015. Epub 2010 Jan 13.


HBV-Specific Adaptive Immunity.

Bertoletti A, Tan AT, Gehring AJ.

Viruses. 2009 Sep;1(2):91-103. doi: 10.3390/v1020091. Epub 2009 Jul 27.


Profile of tumor antigen-specific CD8 T cells in patients with hepatitis B virus-related hepatocellular carcinoma.

Gehring AJ, Ho ZZ, Tan AT, Aung MO, Lee KH, Tan KC, Lim SG, Bertoletti A.

Gastroenterology. 2009 Aug;137(2):682-90. doi: 10.1053/j.gastro.2009.04.045. Epub 2009 Apr 23.


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