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Prader-Willi syndrome imprinting centre deletion mice have impaired baseline and 5-HT2CR-mediated response inhibition.

Davies JR, Wilkinson LS, Isles AR, Humby T.

Hum Mol Genet. 2019 May 14. pii: ddz100. doi: 10.1093/hmg/ddz100. [Epub ahead of print]


Glutamate Transport and Preterm Brain Injury.

Pregnolato S, Chakkarapani E, Isles AR, Luyt K.

Front Physiol. 2019 Apr 24;10:417. doi: 10.3389/fphys.2019.00417. eCollection 2019. Review.


Risk taking and impulsive behaviour: fundamental discoveries, theoretical perspectives and clinical implications.

Isles AR, Winstanley CA, Humby T.

Philos Trans R Soc Lond B Biol Sci. 2019 Feb 18;374(1766):20180128. doi: 10.1098/rstb.2018.0128.


Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance.

Rienecker KDA, Chavasse AT, Moorwood K, Ward A, Isles AR.

Genes Brain Behav. 2019 Apr 1:e12571. doi: 10.1111/gbb.12571. [Epub ahead of print]


Genomic Imprinting and Physiological Processes in Mammals.

Tucci V, Isles AR, Kelsey G, Ferguson-Smith AC; Erice Imprinting Group.

Cell. 2019 Feb 21;176(5):952-965. doi: 10.1016/j.cell.2019.01.043. Review.


Persistence of anxiety symptoms after elective caesarean delivery.

Janssen AB, Savory KA, Garay SM, Sumption L, Watkins W, Garcia-Martin I, Savory NA, Ridgway A, Isles AR, Penketh R, Jones IR, John RM.

BJPsych Open. 2018 Aug 17;4(5):354-360. doi: 10.1192/bjo.2018.48. eCollection 2018 Sep.


Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior.

Dent CL, Humby T, Lewis K, Ward A, Fischer-Colbrie R, Wilkinson LS, Wilkins JF, Isles AR.

Genetics. 2018 May;209(1):233-239. doi: 10.1534/genetics.118.300898. Epub 2018 Mar 21.


Territorial Behavior and Social Stability in the Mouse Require Correct Expression of Imprinted Cdkn1c.

McNamara GI, John RM, Isles AR.

Front Behav Neurosci. 2018 Feb 26;12:28. doi: 10.3389/fnbeh.2018.00028. eCollection 2018.


Htr2c Splice Variants and 5HT2CR-Mediated Appetite.

Isles AR.

Trends Endocrinol Metab. 2017 Aug;28(8):542-544. doi: 10.1016/j.tem.2017.04.002. Epub 2017 May 9.


Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite.

Garfield AS, Davies JR, Burke LK, Furby HV, Wilkinson LS, Heisler LK, Isles AR.

Mol Brain. 2016 Dec 8;9(1):95.


Paradoxical leanness in the imprinting-centre deletion mouse model for Prader-Willi syndrome.

Golding DM, Rees DJ, Davies JR, Relkovic D, Furby HV, Guschina IA, Hopkins AL, Davies JS, Resnick JL, Isles AR, Wells T.

J Endocrinol. 2017 Jan;232(1):123-135. Epub 2016 Oct 31.


Methods of epigenome editing for probing the function of genomic imprinting.

Rienecker KD, Hill MJ, Isles AR.

Epigenomics. 2016 Oct;8(10):1389-1398. Epub 2016 Sep 14.


Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.

Isles AR, Ingason A, Lowther C, Walters J, Gawlick M, Stöber G, Rees E, Martin J, Little RB, Potter H, Georgieva L, Pizzo L, Ozaki N, Aleksic B, Kushima I, Ikeda M, Iwata N, Levinson DF, Gejman PV, Shi J, Sanders AR, Duan J, Willis J, Sisodiya S, Costain G, Werge TM, Degenhardt F, Giegling I, Rujescu D, Hreidarsson SJ, Saemundsen E, Ahn JW, Ogilvie C, Girirajan SD, Stefansson H, Stefansson K, O'Donovan MC, Owen MJ, Bassett A, Kirov G.

PLoS Genet. 2016 May 6;12(5):e1005993. doi: 10.1371/journal.pgen.1005993. eCollection 2016 May.


No Evidence for Enrichment in Schizophrenia for Common Allelic Associations at Imprinted Loci.

Escott-Price V, Kirov G, Rees E, Isles AR, Owen MJ, O'Donovan MC.

PLoS One. 2015 Dec 3;10(12):e0144172. doi: 10.1371/journal.pone.0144172. eCollection 2015.


15q Maternal Duplication and Neurodevelopmental Disorders; UBE3A is the Key.

Isles AR.

Hum Mutat. 2015 Jul;36(7):iii. doi: 10.1002/humu.22656. No abstract available.


Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome.

Davies JR, Humby T, Dwyer DM, Garfield AS, Furby H, Wilkinson LS, Wells T, Isles AR.

Eur J Neurosci. 2015 Aug;42(4):2105-13. doi: 10.1111/ejn.12972. Epub 2015 Jun 25.


An overview of measuring impulsive behavior in mice.

Dent CL, Isles AR.

Curr Protoc Mouse Biol. 2014 Jun 16;4(2):35-45. doi: 10.1002/9780470942390.mo140015. Review.


Influencing the social group: the role of imprinted genes.

McNamara GI, Isles AR.

Adv Genet. 2014;86:107-34. doi: 10.1016/B978-0-12-800222-3.00006-1. Review.


Modelling the genetic contribution to mental illness: a timely end for the psychiatric rodent?

Davis BA, Isles AR.

Eur J Neurosci. 2014 Jun;39(11):1933-42. doi: 10.1111/ejn.12607. Epub 2014 May 24. Review.


Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup.

Cowley M, Garfield AS, Madon-Simon M, Charalambous M, Clarkson RW, Smalley MJ, Kendrick H, Isles AR, Parry AJ, Carney S, Oakey RJ, Heisler LK, Moorwood K, Wolf JB, Ward A.

PLoS Biol. 2014 Feb 25;12(2):e1001799. doi: 10.1371/journal.pbio.1001799. eCollection 2014 Feb.

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