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Items: 10


In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury-Lessons Learned.

Lipponen A, Natunen T, Hujo M, Ciszek R, Hämäläinen E, Tohka J, Hiltunen M, Paananen J, Poulsen D, Kansanen E, Ekolle Ndode-Ekane X, Levonen AL, Pitkänen A.

Int J Mol Sci. 2019 Oct 29;20(21). pii: E5395. doi: 10.3390/ijms20215395.


Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies.

Karttunen J, Heiskanen M, Lipponen A, Poulsen D, Pitkänen A.

Int J Mol Sci. 2019 Mar 13;20(6). pii: E1259. doi: 10.3390/ijms20061259. Review.


Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility.

Kyyriäinen J, Bolkvadze T, Koivisto H, Lipponen A, Pérez LO, Ekolle Ndode-Ekane X, Tanila H, Pitkänen A.

Epilepsy Res. 2019 Mar;151:67-74. doi: 10.1016/j.eplepsyres.2019.02.009. Epub 2019 Feb 25.


Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs.

Karttunen J, Heiskanen M, Navarro-Ferrandis V, Das Gupta S, Lipponen A, Puhakka N, Rilla K, Koistinen A, Pitkänen A.

J Extracell Vesicles. 2018 Dec 18;8(1):1555410. doi: 10.1080/20013078.2018.1555410. eCollection 2019.


Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird.

Soulsbury CD, Lipponen A, Wood K, Mein CA, Hoffman JI, Lebigre C.

Ecol Evol. 2018 May 30;8(13):6547-6557. doi: 10.1002/ece3.4132. eCollection 2018 Jul.


Effect of resource availability on evolution of virulence and competition in an environmentally transmitted pathogen.

Pulkkinen K, Pekkala N, Ashrafi R, Hämäläinen DM, Nkembeng AN, Lipponen A, Hiltunen T, Valkonen JK, Taskinen J.

FEMS Microbiol Ecol. 2018 May 1;94(5). doi: 10.1093/femsec/fiy060.


Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.

Lipponen A, El-Osta A, Kaspi A, Ziemann M, Khurana I, Kn H, Navarro-Ferrandis V, Puhakka N, Paananen J, Pitkänen A.

Acta Neuropathol Commun. 2018 Feb 27;6(1):17. doi: 10.1186/s40478-018-0519-z.


High Nutrient Concentration Can Induce Virulence Factor Expression and Cause Higher Virulence in an Environmentally Transmitted Pathogen.

Penttinen R, Kinnula H, Lipponen A, Bamford JK, Sundberg LR.

Microb Ecol. 2016 Nov;72(4):955-964. Epub 2016 May 19.


Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets.

Lipponen A, Paananen J, Puhakka N, Pitkänen A.

Sci Rep. 2016 Aug 17;6:31570. doi: 10.1038/srep31570.


Gender issues in antiepileptogenic treatments.

Pitkänen A, Huusko N, Ndode-Ekane XE, Kyyriäinen J, Lipponen A, Lipsanen A, Sierra A, Bolkvadze T.

Neurobiol Dis. 2014 Dec;72 Pt B:224-32. doi: 10.1016/j.nbd.2014.05.037. Epub 2014 Jun 6. Review.


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