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Items: 17

1.

Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue.

Ghosheh N, Küppers-Munther B, Asplund A, Andersson CX, Björquist P, Andersson TB, Carén H, Simonsson S, Sartipy P, Synnergren J.

ACS Omega. 2020 Mar 2;5(10):4816-4827. doi: 10.1021/acsomega.9b03514. eCollection 2020 Mar 17.

2.

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases.

Holmgren G, Ulfenborg B, Asplund A, Toet K, Andersson CX, Hammarstedt A, Hanemaaijer R, Küppers-Munther B, Synnergren J.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E469. doi: 10.3390/ijms21020469.

3.

Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.

Ghosheh N, Küppers-Munther B, Asplund A, Edsbagge J, Ulfenborg B, Andersson TB, Björquist P, Andersson CX, Carén H, Simonsson S, Sartipy P, Synnergren J.

Physiol Genomics. 2017 Aug 1;49(8):430-446. doi: 10.1152/physiolgenomics.00007.2017. Epub 2017 Jul 10.

4.

Erratum to: Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days.

Starokozhko V, Vatakuti S, Schievink B, Merema MT, Asplund A, Synnergren J, Aspegren A, Groothuis GMM.

Arch Toxicol. 2017 Jul;91(7):2711. doi: 10.1007/s00204-016-1895-4. No abstract available.

5.

Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days.

Starokozhko V, Vatakuti S, Schievink B, Merema MT, Asplund A, Synnergren J, Aspegren A, Groothuis GMM.

Arch Toxicol. 2017 May;91(5):2079-2092. doi: 10.1007/s00204-016-1865-x. Epub 2016 Oct 7. Erratum in: Arch Toxicol. 2017 Jul;91(7):2711.

6.

Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.

Ghosheh N, Olsson B, Edsbagge J, Küppers-Munther B, Van Giezen M, Asplund A, Andersson TB, Björquist P, Carén H, Simonsson S, Sartipy P, Synnergren J.

Stem Cells Int. 2016;2016:8648356. doi: 10.1155/2016/8648356. Epub 2016 Feb 1.

7.

Corrigendum to "Gene networks and transcription factor motifs defining the differentiation of human stem cells into hepatocyte-like cells" [J Hepatol 2015;63:934-942].

Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Björquist P, Widera A, Stöber R, Campos G, Hammad S, Sachinidis A, Chaudhari U, Damm G, Weiss TS, Nüssler A, Synnergren J, Edlund K, Küppers-Munther B, Hay DC, Hengstler JG.

J Hepatol. 2016 Feb;64(2):525-526. doi: 10.1016/j.jhep.2015.11.003. Epub 2015 Dec 2. No abstract available.

8.

One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.

Asplund A, Pradip A, van Giezen M, Aspegren A, Choukair H, Rehnström M, Jacobsson S, Ghosheh N, El Hajjam D, Holmgren S, Larsson S, Benecke J, Butron M, Wigander A, Noaksson K, Sartipy P, Björquist P, Edsbagge J, Küppers-Munther B.

Stem Cell Rev Rep. 2016 Feb;12(1):90-104. doi: 10.1007/s12015-015-9621-9.

PMID:
26385115
9.

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Björquist P, Widera A, Stöber R, Campos G, Hammad S, Sachinidis A, Chaudhari U, Damm G, Weiss TS, Nüssler A, Synnergren J, Edlund K, Küppers-Munther B, Hay DC, Hengstler JG.

J Hepatol. 2015 Oct;63(4):934-42. doi: 10.1016/j.jhep.2015.05.013. Epub 2015 May 25. Erratum in: J Hepatol. 2016 Feb;64(2):525-6. Erratum in: J Hepatol. 2016 Feb;64(2):525-526.

10.

Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53.

Sayin VI, Khan OM, Pehlivanoglu LE, Staffas A, Ibrahim MX, Asplund A, Agren P, Nilton A, Bergström G, Bergo MO, Borén J, Lindahl P.

Circ Res. 2014 Oct 10;115(9):781-9. doi: 10.1161/CIRCRESAHA.115.304992. Epub 2014 Sep 11.

PMID:
25212213
11.

Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.

Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.

Biochem Pharmacol. 2013 Sep 1;86(5):691-702. doi: 10.1016/j.bcp.2013.06.029. Epub 2013 Jul 12.

PMID:
23856292
12.

The continuing challenge of providing drug information services to diminish the knowledge--practice gap in medical practice.

Alván G, Andersson ML, Asplund AB, Böttiger Y, Elwin CE, Gustafsson LL, Öhman B, Törnqvist E.

Eur J Clin Pharmacol. 2013 May;69 Suppl 1:65-72. doi: 10.1007/s00228-013-1484-x. Epub 2013 May 3.

PMID:
23640190
13.

Macrophages exposed to hypoxia secrete proteoglycans for which LDL has higher affinity.

Asplund A, Fridén V, Stillemark-Billton P, Camejo G, Bondjers G.

Atherosclerosis. 2011 Mar;215(1):77-81. doi: 10.1016/j.atherosclerosis.2010.12.017. Epub 2010 Dec 23.

PMID:
21247579
14.

Metformin for weight reduction in non-diabetic patients on antipsychotic drugs: a systematic review and meta-analysis.

Björkhem-Bergman L, Asplund AB, Lindh JD.

J Psychopharmacol. 2011 Mar;25(3):299-305. doi: 10.1177/0269881109353461. Epub 2010 Jan 15. Review.

PMID:
20080925
15.

Hypoxic regulation of secreted proteoglycans in macrophages.

Asplund A, Stillemark-Billton P, Larsson E, Rydberg EK, Moses J, Hultén LM, Fagerberg B, Camejo G, Bondjers G.

Glycobiology. 2010 Jan;20(1):33-40. doi: 10.1093/glycob/cwp139. Epub 2009 Sep 11.

PMID:
19748976
16.

Hypoxia increases macrophage motility, possibly by decreasing the heparan sulfate proteoglycan biosynthesis.

Asplund A, Ostergren-Lundén G, Camejo G, Stillemark-Billton P, Bondjers G.

J Leukoc Biol. 2009 Aug;86(2):381-8. doi: 10.1189/jlb.0908536. Epub 2009 Apr 28.

PMID:
19401393
17.

[Codeine and breast feeding].

Asplund A, Böttiger Y.

Lakartidningen. 2006 Dec 6-12;103(49):3954. Swedish. No abstract available.

PMID:
17212276

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