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Items: 1 to 20 of 81

1.

Counteracting in Vitro Toxicity of the Ionophoric Mycotoxin Beauvericin-Synthetic Receptors to the Rescue.

Ornelis V, Rajkovic A, Decleer M, Sas B, De Saeger S, Madder A.

J Org Chem. 2019 Aug 16;84(16):10422-10435. doi: 10.1021/acs.joc.9b01665. Epub 2019 Aug 8.

PMID:
31393120
2.

Teixobactins: a new class of 21st century antibiotics to combat multidrug-resistant bacterial pathogens.

Iyer A, Madder A, Singh I.

Future Microbiol. 2019 Apr;14:457-460. doi: 10.2217/fmb-2019-0056. Epub 2019 Apr 29. No abstract available.

PMID:
31033354
3.

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.

Dejonghe W, Sharma I, Denoo B, De Munck S, Lu Q, Mishev K, Bulut H, Mylle E, De Rycke R, Vasileva M, Savatin DV, Nerinckx W, Staes A, Drozdzecki A, Audenaert D, Yperman K, Madder A, Friml J, Van Damme D, Gevaert K, Haucke V, Savvides SN, Winne J, Russinova E.

Nat Chem Biol. 2019 Jun;15(6):641-649. doi: 10.1038/s41589-019-0262-1. Epub 2019 Apr 22.

PMID:
31011214
4.

Furan Cross-Linking Technology for Investigating GPCR-Ligand Interactions.

Van Troys M, Vannecke W, Ampe C, Madder A.

Methods Mol Biol. 2019;1947:81-102. doi: 10.1007/978-1-4939-9121-1_5.

PMID:
30969412
5.

Thermoresponsive DNA by Intercalation of dsDNA with Oligoethylene-Glycol-Functionalized Small-Molecule Intercalators.

Bera D, Verdonck L, Glassner M, Madder A, Hoogenboom R.

Macromol Rapid Commun. 2019 May;40(10):e1800900. doi: 10.1002/marc.201800900. Epub 2019 Feb 6.

PMID:
30725517
6.

Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization.

Verdonck L, Buyst D, de Vries AM, Gheerardijn V, Madder A, Martins JC.

Nucleic Acids Res. 2018 Dec 14;46(22):11671-11686. doi: 10.1093/nar/gky1062.

7.

Pyrrole-Mediated Peptide Cyclization Identified through Genetically Reprogrammed Peptide Synthesis.

Decoene KW, Vannecke W, Passioura T, Suga H, Madder A.

Biomedicines. 2018 Oct 30;6(4). pii: E99. doi: 10.3390/biomedicines6040099.

8.

Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides.

Martin C, Dumitrascuta M, Mannes M, Lantero A, Bucher D, Walker K, Van Wanseele Y, Oyen E, Hernot S, Van Eeckhaut A, Madder A, Hoogenboom R, Spetea M, Ballet S.

J Med Chem. 2018 Nov 8;61(21):9784-9789. doi: 10.1021/acs.jmedchem.8b01282. Epub 2018 Oct 26.

PMID:
30351003
9.

Development of a Synthetic Receptor for the Food Toxin Beauvericin: A Tale of Carbazole and Steroids.

Ornelis V, Rajkovic A, Sas B, De Saeger S, Madder A.

Org Lett. 2018 Oct 19;20(20):6368-6371. doi: 10.1021/acs.orglett.8b02630. Epub 2018 Oct 10.

PMID:
30336675
10.

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA).

Malkawi R, Iyer A, Parmar A, Lloyd DG, Leng Goh ET, Taylor EJ, Sarmad S, Madder A, Lakshminarayanan R, Singh I.

Pharmaceutics. 2018 Oct 11;10(4). pii: E183. doi: 10.3390/pharmaceutics10040183.

11.

Reviving old protecting group chemistry for site-selective peptide-protein conjugation.

Gunnoo SB, Iyer A, Vannecke W, Decoene KW, Hebbrecht T, Gettemans J, Laga M, Loverix S, Lasters I, Madder A.

Chem Commun (Camb). 2018 Oct 28;54(84):11929-11932. doi: 10.1039/c8cc06684a. Epub 2018 Oct 4.

PMID:
30285017
12.

An Anticaffeine Antibody-Oligonucleotide Conjugate for DNA-Directed Immobilization in Environmental Immunoarrays.

Carvalho AM, Montes CV, Schneider RJ, Madder A.

Langmuir. 2018 Dec 11;34(49):14834-14841. doi: 10.1021/acs.langmuir.8b01347. Epub 2018 Aug 22.

PMID:
30089211
13.

Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.

Mishev K, Lu Q, Denoo B, Peurois F, Dejonghe W, Hullaert J, De Rycke R, Boeren S, Bretou M, De Munck S, Sharma I, Goodman K, Kalinowska K, Storme V, Nguyen LSL, Drozdzecki A, Martins S, Nerinckx W, Audenaert D, Vert G, Madder A, Otegui MS, Isono E, Savvides SN, Annaert W, De Vries S, Cherfils J, Winne J, Russinova E.

Plant Cell. 2018 Oct;30(10):2573-2593. doi: 10.1105/tpc.18.00145. Epub 2018 Jul 17.

PMID:
30018157
14.

Oxygen Consumption Rate Analysis of Mitochondrial Dysfunction Caused by Bacillus cereus Cereulide in Caco-2 and HepG2 Cells.

Decleer M, Jovanovic J, Vakula A, Udovicki B, Agoua REK, Madder A, De Saeger S, Rajkovic A.

Toxins (Basel). 2018 Jul 2;10(7). pii: E266. doi: 10.3390/toxins10070266.

15.

Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.

Parmar A, Iyer A, Prior SH, Lloyd DG, Leng Goh ET, Vincent CS, Palmai-Pallag T, Bachrati CZ, Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I.

Chem Sci. 2017 Dec 1;8(12):8183-8192. doi: 10.1039/c7sc03241b. Epub 2017 Oct 5.

16.

Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo.

Parmar A, Lakshminarayanan R, Iyer A, Mayandi V, Leng Goh ET, Lloyd DG, Chalasani MLS, Verma NK, Prior SH, Beuerman RW, Madder A, Taylor EJ, Singh I.

J Med Chem. 2018 Mar 8;61(5):2009-2017. doi: 10.1021/acs.jmedchem.7b01634. Epub 2018 Feb 15.

PMID:
29363971
17.

A Thiolactone Strategy for Straightforward Synthesis of Disulfide-Linked Side-Chain-to-Tail Cyclic Peptides Featuring an N-Terminal Modification Handle.

Van Lysebetten D, Felissati S, Antonatou E, Carrette LLG, Espeel P, Focquet E, Du Prez FE, Madder A.

Chembiochem. 2018 Mar 16;19(6):641-646. doi: 10.1002/cbic.201700323. Epub 2018 Feb 20.

PMID:
29314620
18.

Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs.

Elskens J, Manicardi A, Costi V, Madder A, Corradini R.

Molecules. 2017 Nov 20;22(11). pii: E2010. doi: 10.3390/molecules22112010.

19.

Singlet oxygen-mediated one-pot chemoselective peptide-peptide ligation.

Antonatou E, Verleysen Y, Madder A.

Org Biomol Chem. 2017 Oct 4;15(38):8140-8144. doi: 10.1039/c7ob02245j.

PMID:
28914947
20.

Visible-Light-Mediated Selective Arylation of Cysteine in Batch and Flow.

Bottecchia C, Rubens M, Gunnoo SB, Hessel V, Madder A, Noël T.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12702-12707. doi: 10.1002/anie.201706700. Epub 2017 Sep 1.

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