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Items: 1 to 20 of 44

1.
2.

7-Ketocholesterol and 7β-hydroxycholesterol: In vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity.

Vejux A, Abed-Vieillard D, Hajji K, Zarrouk A, Mackrill JJ, Ghosh S, Nury T, Yammine A, Zaibi M, Mihoubi W, Bouchab H, Nasser B, Grosjean Y, Lizard G.

Biochem Pharmacol. 2020 Mar;173:113648. doi: 10.1016/j.bcp.2019.113648. Epub 2019 Oct 3. Review.

PMID:
31586589
3.

Peroxisomes in Immune Response and Inflammation.

Di Cara F, Andreoletti P, Trompier D, Vejux A, Bülow MH, Sellin J, Lizard G, Cherkaoui-Malki M, Savary S.

Int J Mol Sci. 2019 Aug 8;20(16). pii: E3877. doi: 10.3390/ijms20163877. Review.

4.

Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol.

Sghaier R, Nury T, Leoni V, Caccia C, Pais De Barros JP, Cherif A, Vejux A, Moreau T, Limem K, Samadi M, Mackrill JJ, Masmoudi AS, Lizard G, Zarrouk A.

J Steroid Biochem Mol Biol. 2019 Nov;194:105432. doi: 10.1016/j.jsbmb.2019.105432. Epub 2019 Jul 22.

PMID:
31344443
5.

Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes.

Sghaier R, Zarrouk A, Nury T, Badreddine I, O'Brien N, Mackrill JJ, Vejux A, Samadi M, Nasser B, Caccia C, Leoni V, Moreau T, Cherkaoui-Malki M, Salhedine Masmoudi A, Lizard G.

Free Radic Res. 2019 May;53(5):535-561. doi: 10.1080/10715762.2019.1612891. Erratum in: Free Radic Res. 2019;53(sup1):I.

PMID:
31039616
6.

Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model.

Doria M, Nury T, Delmas D, Moreau T, Lizard G, Vejux A.

Free Radic Biol Med. 2019 Jun;137:46-58. doi: 10.1016/j.freeradbiomed.2019.04.016. Epub 2019 Apr 17.

PMID:
31004752
7.

Induction of Neuronal Differentiation of Murine N2a Cells by Two Polyphenols Present in the Mediterranean Diet Mimicking Neurotrophins Activities: Resveratrol and Apigenin.

Namsi A, Nury T, Hamdouni H, Yammine A, Vejux A, Vervandier-Fasseur D, Latruffe N, Masmoudi-Kouki O, Lizard G.

Diseases. 2018 Jul 22;6(3). pii: E67. doi: 10.3390/diseases6030067.

8.

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.

Nury T, Sghaier R, Zarrouk A, Ménétrier F, Uzun T, Leoni V, Caccia C, Meddeb W, Namsi A, Sassi K, Mihoubi W, Riedinger JM, Cherkaoui-Malki M, Moreau T, Vejux A, Lizard G.

Biochimie. 2018 Oct;153:181-202. doi: 10.1016/j.biochi.2018.07.009. Epub 2018 Jul 19.

PMID:
30031877
9.

Cytoprotective Activities of Milk Thistle Seed Oil Used in Traditional Tunisian Medicine on 7-Ketocholesterol and 24S-Hydroxycholesterol-Induced Toxicity on 158N Murine Oligodendrocytes.

Meddeb W, Rezig L, Zarrouk A, Nury T, Vejux A, Prost M, Bretillon L, Mejri M, Lizard G.

Antioxidants (Basel). 2018 Jul 19;7(7). pii: E95. doi: 10.3390/antiox7070095.

10.

Prevention of 7-ketocholesterol-induced side effects by natural compounds.

Brahmi F, Vejux A, Sghaier R, Zarrouk A, Nury T, Meddeb W, Rezig L, Namsi A, Sassi K, Yammine A, Badreddine I, Vervandier-Fasseur D, Madani K, Boulekbache-Makhlouf L, Nasser B, Lizard G.

Crit Rev Food Sci Nutr. 2019;59(19):3179-3198. doi: 10.1080/10408398.2018.1491828. Epub 2018 Oct 16. Review.

PMID:
29993272
11.

The effect of oxysterols on nerve impulses.

Bezine M, Namsi A, Sghaier R, Ben Khalifa R, Hamdouni H, Brahmi F, Badreddine I, Mihoubi W, Nury T, Vejux A, Zarrouk A, de Sèze J, Moreau T, Nasser B, Lizard G.

Biochimie. 2018 Oct;153:46-51. doi: 10.1016/j.biochi.2018.04.013. Epub 2018 Apr 21. Review.

PMID:
29684511
12.

Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0).

Bezine M, Maatoug S, Ben Khalifa R, Debbabi M, Zarrouk A, Wang Y, Griffiths WJ, Nury T, Samadi M, Vejux A, de Sèze J, Moreau T, Kharrat R, El Ayeb M, Lizard G.

Biochimie. 2018 Oct;153:56-69. doi: 10.1016/j.biochi.2018.02.008. Epub 2018 Feb 17.

PMID:
29462682
13.

Biomarkers of Amyotrophic Lateral Sclerosis: Current Status and Interest of Oxysterols and Phytosterols.

Vejux A, Namsi A, Nury T, Moreau T, Lizard G.

Front Mol Neurosci. 2018 Jan 31;11:12. doi: 10.3389/fnmol.2018.00012. eCollection 2018. Review.

14.

Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.

Badreddine A, Zarrouk A, Karym EM, Debbabi M, Nury T, Meddeb W, Sghaier R, Bezine M, Vejux A, Martine L, Grégoire S, Bretillon L, Prost-Camus E, Durand P, Prost M, Moreau T, Cherkaoui-Malki M, Nasser B, Lizard G.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2220. doi: 10.3390/ijms18102220.

15.

Flow Cytometric Analysis of the Expression Pattern of Peroxisomal Proteins, Abcd1, Abcd2, and Abcd3 in BV-2 Murine Microglial Cells.

Debbabi M, Nury T, Helali I, Karym EM, Geillon F, Gondcaille C, Trompier D, Najid A, Terreau S, Bezine M, Zarrouk A, Vejux A, Andreoletti P, Cherkaoui-Malki M, Savary S, Lizard G.

Methods Mol Biol. 2017;1595:257-265. doi: 10.1007/978-1-4939-6937-1_25.

PMID:
28409470
16.

Evidence of K+ homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes.

Bezine M, Debbabi M, Nury T, Ben-Khalifa R, Samadi M, Cherkaoui-Malki M, Vejux A, Raas Q, de Sèze J, Moreau T, El-Ayeb M, Lizard G.

Chem Phys Lipids. 2017 Oct;207(Pt B):135-150. doi: 10.1016/j.chemphyslip.2017.03.006. Epub 2017 Mar 18.

PMID:
28322741
17.

Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells.

Brahmi F, Hadj-Ahmed S, Zarrouk A, Bezine M, Nury T, Madani K, Chibane M, Vejux A, Andreoletti P, Boulekbache-Makhlouf L, Lizard G.

Pharm Biol. 2017 Dec;55(1):286-293.

18.

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Debbabi M, Nury T, Zarrouk A, Mekahli N, Bezine M, Sghaier R, Grégoire S, Martine L, Durand P, Camus E, Vejux A, Jabrane A, Bretillon L, Prost M, Moreau T, Ammou SB, Hammami M, Lizard G.

Int J Mol Sci. 2016 Nov 25;17(12). pii: E1973.

19.

Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease.

Doria M, Maugest L, Moreau T, Lizard G, Vejux A.

Free Radic Biol Med. 2016 Dec;101:393-400. doi: 10.1016/j.freeradbiomed.2016.10.008. Epub 2016 Nov 9. Review.

PMID:
27836779
20.

7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD.

Nury T, Zarrouk A, Ragot K, Debbabi M, Riedinger JM, Vejux A, Aubourg P, Lizard G.

J Steroid Biochem Mol Biol. 2017 May;169:123-136. doi: 10.1016/j.jsbmb.2016.03.037. Epub 2016 Apr 1.

PMID:
27041118

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