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Items: 17


Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.

Posadino AM, Giordo R, Cossu A, Nasrallah GK, Shaito A, Abou-Saleh H, Eid AH, Pintus G.

Biomolecules. 2019 May 30;9(6). pii: E209. doi: 10.3390/biom9060209.


Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients.

Fois AG, Posadino AM, Giordo R, Cossu A, Agouni A, Rizk NM, Pirina P, Carru C, Zinellu A, Pintus G.

Oxid Med Cell Longev. 2018 Oct 21;2018:2639081. doi: 10.1155/2018/2639081. eCollection 2018.


Protective Effect of Cyclically Pressurized Solid⁻Liquid Extraction Polyphenols from Cagnulari Grape Pomace on Oxidative Endothelial Cell Death.

Posadino AM, Biosa G, Zayed H, Abou-Saleh H, Cossu A, Nasrallah GK, Giordo R, Pagnozzi D, Porcu MC, Pretti L, Pintus G.

Molecules. 2018 Aug 21;23(9). pii: E2105. doi: 10.3390/molecules23092105.


Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells.

Posadino AM, Phu HT, Cossu A, Giordo R, Fois M, Thuan DTB, Piga A, Sotgia S, Zinellu A, Carru C, Pintus G.

Toxicol In Vitro. 2017 Aug;42:255-262. doi: 10.1016/j.tiv.2017.05.005. Epub 2017 May 7.


N- and S-homocysteinylation reduce the binding of human serum albumin to catechins.

Zinellu A, Sotgia S, Scanu B, Arru D, Cossu A, Posadino AM, Giordo R, Mangoni AA, Pintus G, Carru C.

Eur J Nutr. 2017 Mar;56(2):785-791. doi: 10.1007/s00394-015-1125-5. Epub 2015 Dec 10.


Human Serum Albumin Increases the Stability of Green Tea Catechins in Aqueous Physiological Conditions.

Zinellu A, Sotgia S, Scanu B, Forteschi M, Giordo R, Cossu A, Posadino AM, Carru C, Pintus G.

PLoS One. 2015 Jul 31;10(7):e0134690. doi: 10.1371/journal.pone.0134690. eCollection 2015.


Resveratrol alters human endothelial cells redox state and causes mitochondrial-dependent cell death.

Posadino AM, Cossu A, Giordo R, Zinellu A, Sotgia S, Vardeu A, Hoa PT, Nguyen le HV, Carru C, Pintus G.

Food Chem Toxicol. 2015 Apr;78:10-6. doi: 10.1016/j.fct.2015.01.017. Epub 2015 Feb 2.


Evaluation of non-covalent interactions between serum albumin and green tea catechins by affinity capillary electrophoresis.

Zinellu A, Sotgia S, Scanu B, Pisanu E, Giordo R, Cossu A, Posadino AM, Carru C, Pintus G.

J Chromatogr A. 2014 Nov 7;1367:167-71. doi: 10.1016/j.chroma.2014.09.053. Epub 2014 Sep 30.


Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension.

Boin F, Erre GL, Posadino AM, Cossu A, Giordo R, Spinetti G, Passiu G, Emanueli C, Pintus G.

Orphanet J Rare Dis. 2014 Aug 1;9:123. doi: 10.1186/s13023-014-0123-7.


Different redox response elicited by naturally occurring antioxidants in human endothelial cells.

Giordo R, Cossu A, Pasciu V, Hoa PT, Posadino AM, Pintus G.

Open Biochem J. 2013 Apr 19;7:44-53. doi: 10.2174/1874091X01307010044. Print 2013.


Coumaric acid induces mitochondrial damage and oxidative-mediated cell death of human endothelial cells.

Posadino AM, Cossu A, Giordo R, Zinellu A, Sotgia S, Vardeu A, Hoa PT, Deiana L, Carru C, Pintus G.

Cardiovasc Toxicol. 2013 Sep;13(3):301-6. doi: 10.1007/s12012-013-9205-3.


Apricot melanoidins prevent oxidative endothelial cell death by counteracting mitochondrial oxidation and membrane depolarization.

Cossu A, Posadino AM, Giordo R, Emanueli C, Sanguinetti AM, Piscopo A, Poiana M, Capobianco G, Piga A, Pintus G.

PLoS One. 2012;7(11):e48817. doi: 10.1371/journal.pone.0048817. Epub 2012 Nov 8.


Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.

Sanna V, Roggio AM, Posadino AM, Cossu A, Marceddu S, Mariani A, Alzari V, Uzzau S, Pintus G, Sechi M.

Nanoscale Res Lett. 2011 Mar 28;6(1):260. doi: 10.1186/1556-276X-6-260.


Prune melanoidins protect against oxidative stress and endothelial cell death.

Posadino AM, Cossu A, Piga A, Madrau MA, Del Caro A, Colombino M, Paglietti B, Rubino S, Iaccarino C, Crosio C, Sanna B, Pintus G.

Front Biosci (Elite Ed). 2011 Jun 1;3:1034-41.


Akt downregulation by flavin oxidase-induced ROS generation mediates dose-dependent endothelial cell damage elicited by natural antioxidants.

Pasciu V, Posadino AM, Cossu A, Sanna B, Tadolini B, Gaspa L, Marchisio A, Dessole S, Capobianco G, Pintus G.

Toxicol Sci. 2010 Mar;114(1):101-12. doi: 10.1093/toxsci/kfp301. Epub 2009 Dec 15.


S-homocysteinylated LDL apolipoprotein B adversely affects human endothelial cells in vitro.

Zinellu A, Sotgia S, Scanu B, Pintus G, Posadino AM, Cossu A, Deiana L, Sengupta S, Carru C.

Atherosclerosis. 2009 Sep;206(1):40-6. doi: 10.1016/j.atherosclerosis.2009.01.035. Epub 2009 Feb 3.


NAMI-A inhibits the PMA-induced ODC gene expression in ECV304 cells: involvement of PKC/Raf/Mek/ERK signalling pathway.

Debidda M, Sanna B, Cossu A, Posadino AM, Tadolini B, Ventura C, Pintus G.

Int J Oncol. 2003 Aug;23(2):477-82.


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