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Items: 1 to 20 of 23

1.

Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication.

Merlino F, Tomassi S, Yousif AM, Messere A, Marinelli L, Grieco P, Novellino E, Cosconati S, Di Maro S.

Org Lett. 2019 Aug 16;21(16):6378-6382. doi: 10.1021/acs.orglett.9b02283. Epub 2019 Jul 30.

PMID:
31361506
2.

Cationic nucleopeptides as novel non-covalent carriers for the delivery of peptide nucleic acid (PNA) and RNA oligomers.

Tomassi S, IeranĂ² C, Mercurio ME, Nigro E, Daniele A, Russo R, Chambery A, Baglivo I, Pedone PV, Rea G, Napolitano M, Scala S, Cosconati S, Marinelli L, Novellino E, Messere A, Di Maro S.

Bioorg Med Chem. 2018 May 15;26(9):2539-2550. doi: 10.1016/j.bmc.2018.04.017. Epub 2018 Apr 7.

PMID:
29656988
3.

Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist.

Di Maro S, Di Leva FS, Trotta AM, Brancaccio D, Portella L, Aurilio M, Tomassi S, Messere A, Sementa D, Lastoria S, Carotenuto A, Novellino E, Scala S, Marinelli L.

J Med Chem. 2017 Dec 14;60(23):9641-9652. doi: 10.1021/acs.jmedchem.7b01062. Epub 2017 Nov 20.

PMID:
29125295
4.

Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.

Giustiniano M, Daniele S, Pelliccia S, La Pietra V, Pietrobono D, Brancaccio D, Cosconati S, Messere A, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Taliani S, La Regina G, Da Settimo F, Silvestri R, Martini C, Novellino E, Marinelli L.

J Med Chem. 2017 Oct 12;60(19):8115-8130. doi: 10.1021/acs.jmedchem.7b00912. Epub 2017 Sep 30.

PMID:
28921985
5.

Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO).

Milite C, Barresi E, Da Pozzo E, Costa B, Viviano M, Porta A, Messere A, Sbardella G, Da Settimo F, Novellino E, Cosconati S, Castellano S, Taliani S, Martini C.

J Med Chem. 2017 Sep 28;60(18):7897-7909. doi: 10.1021/acs.jmedchem.7b01031. Epub 2017 Sep 15.

PMID:
28858490
6.

Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer.

Morgillo F, Amendola G, Della Corte CM, Giacomelli C, Botta L, Di Maro S, Messere A, Ciaramella V, Taliani S, Marinelli L, Trincavelli ML, Martini C, Novellino E, Ciardiello F, Cosconati S.

J Med Chem. 2017 Sep 14;60(17):7447-7458. doi: 10.1021/acs.jmedchem.7b00794. Epub 2017 Aug 22.

PMID:
28787156
7.

Switchable Protecting Strategy for Solid Phase Synthesis of DNA and RNA Interacting Nucleopeptides.

Mercurio ME, Tomassi S, Gaglione M, Russo R, Chambery A, Lama S, Stiuso P, Cosconati S, Novellino E, Di Maro S, Messere A.

J Org Chem. 2016 Dec 2;81(23):11612-11625. Epub 2016 Nov 8.

PMID:
27791366
8.

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis.

Olivieri M, Ferro M, Terreri S, Durso M, Romanelli A, Avitabile C, De Cobelli O, Messere A, Bruzzese D, Vannini I, Marinelli L, Novellino E, Zhang W, Incoronato M, Ilardi G, Staibano S, Marra L, Franco R, PerdonĂ  S, Terracciano D, Czerniak B, Liguori GL, Colonna V, Fabbri M, Febbraio F, Calin GA, Cimmino A.

Oncotarget. 2016 Apr 12;7(15):20636-54. doi: 10.18632/oncotarget.7833.

9.

Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells.

Durso M, Gaglione M, Piras L, Mercurio ME, Terreri S, Olivieri M, Marinelli L, Novellino E, Incoronato M, Grieco P, Orsini G, Tonon G, Messere A, Cimmino A.

Eur J Med Chem. 2016 Mar 23;111:15-25. doi: 10.1016/j.ejmech.2016.01.047. Epub 2016 Jan 27.

PMID:
26854374
10.

Hairpin oligonucleotides forming G-quadruplexes: new aptamers with anti-HIV activity.

Romanucci V, Gaglione M, Messere A, Potenza N, Zarrelli A, Noppen S, Liekens S, Balzarini J, Di Fabio G.

Eur J Med Chem. 2015 Jan 7;89:51-8. doi: 10.1016/j.ejmech.2014.10.030. Epub 2014 Oct 14.

PMID:
25462225
11.

Synthesis and gene silencing properties of siRNAs containing terminal amide linkages.

Gaglione M, Mercurio ME, Potenza N, Mosca N, Russo A, Novellino E, Cosconati S, Messere A.

Biomed Res Int. 2014;2014:901617. doi: 10.1155/2014/901617. Epub 2014 Mar 26.

12.

Synthesis, biophysical characterization and anti-HIV activity of d(TG3AG) Quadruplexes bearing hydrophobic tails at the 5'-end.

Romanucci V, Milardi D, Campagna T, Gaglione M, Messere A, D'Urso A, Crisafi E, La Rosa C, Zarrelli A, Balzarini J, Di Fabio G.

Bioorg Med Chem. 2014 Feb 1;22(3):960-6. doi: 10.1016/j.bmc.2013.12.051. Epub 2014 Jan 4.

PMID:
24433967
13.

Synthesis and biological properties of caffeic acid-PNA dimers containing guanine.

Gaglione M, Malgieri G, Pacifico S, Severino V, D'Abrosca B, Russo L, Fiorentino A, Messere A.

Molecules. 2013 Jul 31;18(8):9147-62. doi: 10.3390/molecules18089147.

14.

Tuning RNA Interference by Enhancing siRNA/PAZ Recognition.

Gaglione M, Potenza N, Di Fabio G, Romanucci V, Mosca N, Russo A, Novellino E, Cosconati S, Messere A.

ACS Med Chem Lett. 2012 Nov 16;4(1):75-8. doi: 10.1021/ml300284b. eCollection 2013 Jan 10.

15.

A novel synthetic strategy for monosubstituted cyclodextrin derivatives.

Di Fabio G, Malgieri G, Isernia C, D'Onofrio J, Gaglione M, Messere A, Zarrelli A, De Napoli L.

Chem Commun (Camb). 2012 Apr 21;48(32):3875-7. doi: 10.1039/c2cc30550j. Epub 2012 Mar 14.

PMID:
22415157
16.

An alternative strategy to synthesize PNA and DNA magnetic conjugates forming nanoparticle assembly based on PNA/DNA duplexes.

Milano G, Musumeci D, Gaglione M, Messere A.

Mol Biosyst. 2010 Mar;6(3):553-61. doi: 10.1039/b915680a. Epub 2009 Dec 11.

PMID:
20174683
17.

RNA interference in mammalia cells by RNA-3'-PNA chimeras.

Potenza N, Moggio L, Milano G, Salvatore V, Di Blasio B, Russo A, Messere A.

Int J Mol Sci. 2008 Mar;9(3):299-315. Epub 2008 Mar 12.

18.

Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.

Moggio L, Romanelli A, Gambari R, Bianchi N, Borgatti M, Fabbri E, Mancini I, di Blasio B, Pedone C, Messere A.

Biopolymers. 2007;88(6):815-22.

PMID:
17918186
19.

Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine.

Messere A, Fabbri E, Borgatti M, Gambari R, Di Blasio B, Pedone C, Romanelli A.

J Inorg Biochem. 2007 Feb;101(2):254-60. Epub 2006 Oct 1.

PMID:
17097738
20.

Solid-phase synthesis of cyclic PNA and PNA-DNA chimeras.

Moggio L, De Napoli L, Di Blasio B, Di Fabio G, D'Onofrio J, Montesarchio D, Messere A.

Org Lett. 2006 May 11;8(10):2015-8.

PMID:
16671770

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