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Items: 15

1.

(Z)-Oxopropene-1,3-diyl, a Linker for the Conjugation of the Thiol Group of Cysteine with Amino-Derivatized Drugs.

Petit E, Bosch L, Costa AM, Vilarrasa J.

J Org Chem. 2019 Sep 6;84(17):11170-11176. doi: 10.1021/acs.joc.8b02686. Epub 2019 Aug 26.

PMID:
31409066
2.

Involvement of PPARγ in the Anticonvulsant Activity of EP-80317, a Ghrelin Receptor Antagonist.

Lucchi C, Costa AM, Giordano C, Curia G, Piat M, Leo G, Vinet J, Brunel L, Fehrentz JA, Martinez J, Torsello A, Biagini G.

Front Pharmacol. 2017 Sep 22;8:676. doi: 10.3389/fphar.2017.00676. eCollection 2017.

3.

Formal Total Synthesis of Amphidinolide E.

Bosch L, Mola L, Petit E, Saladrigas M, Esteban J, Costa AM, Vilarrasa J.

J Org Chem. 2017 Oct 20;82(20):11021-11034. doi: 10.1021/acs.joc.7b01973. Epub 2017 Oct 6.

PMID:
28956439
4.

The Performance of Several Docking Programs at Reproducing Protein-Macrolide-Like Crystal Structures.

Castro-Alvarez A, Costa AM, Vilarrasa J.

Molecules. 2017 Jan 17;22(1). pii: E136. doi: 10.3390/molecules22010136.

5.

Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons.

Giordano C, Costa AM, Lucchi C, Leo G, Brunel L, Fehrentz JA, Martinez J, Torsello A, Biagini G.

Front Cell Neurosci. 2016 Dec 16;10:281. doi: 10.3389/fncel.2016.00281. eCollection 2016.

6.

Total Synthesis of Amphidinolide K, a Macrolide That Stabilizes F-Actin.

Sánchez D, Andreou T, Costa AM, Meyer KG, Williams DR, Barasoain I, Díaz JF, Lucena-Agell D, Vilarrasa J.

J Org Chem. 2015 Sep 4;80(17):8511-9. doi: 10.1021/acs.joc.5b00966. Epub 2015 Jun 23.

PMID:
26079383
7.

Tosvinyl and besvinyl as protecting groups of imides, azinones, nucleosides, sultams, and lactams. Catalytic conjugate additions to tosylacetylene.

Petit E, Bosch L, Font J, Mola L, Costa AM, Vilarrasa J.

J Org Chem. 2014 Sep 19;79(18):8826-34. doi: 10.1021/jo501647w. Epub 2014 Sep 9.

PMID:
25162376
8.

Nucleophile-catalyzed additions to activated triple bonds. Protection of lactams, imides, and nucleosides with MocVinyl and related groups.

Mola L, Font J, Bosch L, Caner J, Costa AM, Etxebarría-Jardí G, Pineda O, de Vicente D, Vilarrasa J.

J Org Chem. 2013 Jun 21;78(12):5832-42. doi: 10.1021/jo4006409. Epub 2013 Jun 3.

9.

Iododesilylation of TIPS-, TBDPS-, and TBS-substituted alkenes in connection with the synthesis of amphidinolides B/D.

Sidera M, Costa AM, Vilarrasa J.

Org Lett. 2011 Sep 16;13(18):4934-7. doi: 10.1021/ol2020187. Epub 2011 Aug 25.

PMID:
21866884
10.

Synthesis of amphidinolide E C10-C26 fragment.

Esteban J, Costa AM, Vilarrasa J.

Org Lett. 2008 Nov 6;10(21):4843-6. doi: 10.1021/ol801923y. Epub 2008 Oct 7.

PMID:
18837554
11.

Michael addition-elimination reactions of chiral enolates with ethyl 3-halopropenoates.

Esteban J, Costa AM, Gómez A, Vilarrasa J.

Org Lett. 2008 Jan 3;10(1):65-8. Epub 2007 Dec 11.

PMID:
18069842
13.

Synthesis of (-)-amphidinolide K fragment C9-C22.

Andreou T, Costa AM, Esteban L, Gonzàlez L, Mas G, Vilarrasa J.

Org Lett. 2005 Sep 15;7(19):4083-6.

PMID:
16146357
14.

A formal total synthesis of eleutherobin through an unprecedented kinetically controlled ring-closing-metathesis reaction of a densely functionalized diene.

Castoldi D, Caggiano L, Panigada L, Sharon O, Costa AM, Gennari C.

Angew Chem Int Ed Engl. 2005 Jan 14;44(4):588-91. No abstract available.

PMID:
15597390
15.

Optimization of catalyst enantioselectivity and activity using achiral and meso ligands.

Costa AM, Jimeno C, Gavenonis J, Carroll PJ, Walsh PJ.

J Am Chem Soc. 2002 Jun 19;124(24):6929-41.

PMID:
12059216

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